NEUROTROPHY

作品数:19被引量:19H指数:3
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相关领域:医药卫生更多>>
相关期刊:《Medicinal Plant》《Acta Pharmacologica Sinica》《Precision Medicine Research》《Journal of Hainan Medical University》更多>>
相关基金:国家自然科学基金北京市自然科学基金更多>>
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Antidepressant-like Effects of Flavonoids from Pteridium aquilinum var.latiusculum
《Medicinal Plant》2023年第1期55-63,共9页Zimeng FENG Xiang HAN Shuangli LIU Xiaohui WANG 
Supported by the Innovation Project of Jilin Academy of Agricultural Sciences(cxgc2017zy011);Major Project of Jilin Province Science and Technology Department(20170204046ny).
[Objectives]To explore the antidepressant-like effects of PAFL and its potential mechanisms.[Methods]This study used PAFL in mice under various conditions and analyzed the results.The antidepressant-like effects of fl...
关键词:Pteridium aquilinum var.latiusculum Central nervous system LPS-induced depression Inflammation NEUROTROPHY 
Protective effects of modified Wendan decoction on hippocampal neurons in a rat model of depression
《Precision Medicine Research》2021年第4期19-22,共4页Li-Ping Zhang Yun-Sha Zhang Ting Xue Shan-Yan Yin Ying Chen Lei Xu Rui-Wen Song 
The work was supported by the National Natural Science Foundation of China(No.81673911).
Objective:To study the effects of modified Wendan decoction on hippocampal neuron plasticity in a rat model of depression.Methods:Thirty-two rats were randomly divided into a blank control group,model group,traditiona...
关键词:DEPRESSION modified Wendan decoction neuron plasticity NEUROTROPHY 
Effect of the modified wendan decoction on hippocampal astrocyte neurotrophy by regulating the TRP-KYN metabolic pathway in depression-model rats
《TMR Pharmacology Research》2021年第4期1-8,共8页Ying Chen Li-Ping Zhang Lei Xu Rui-Wen Song 
This research was supported by National Natural Science Foundation of China(81673911).
Objective:To observe the effect of the modified Wendan decoction on the neurotrophic function of hippocampal astrocytes by regulating the tryptophan-kynurenine(TRP-KYN)neuroprotective metabolic pathway in depression-m...
关键词:modified wendan decoction DEPRESSION TRP-KYN metabolic pathway ASTROCYTES rats 
DL0410 ameliorates cognitive disorder in SAMP8 mice by promoting mitochondrial dynamics and the NMDAR-CREB-BDNF pathway被引量:7
《Acta Pharmacologica Sinica》2021年第7期1055-1068,共14页Wen-wen Lian Wei Zhou Bao-yue Zhang Hao Jia Lv-jie Xu Ai-lin Liu Guan-hua Du 
The study was supported by the National Great Science Technology Projects(2014ZX09507003-002);the Drug Innovation Major Project(No.2018ZX09711001-003-002);the CAMS Initiative for Innovative Medicine(CAMS-IZM)(2016-IZM-3-007);the Beijing Natural Science Foundation(7192134,7204303);and the National Natural Science Foundation of China(81673480).
Alzheimer’s disease (AD) is a worldwide problem and there are no effective drugs for AD treatment. Previous studies show that DL0410 is a multi-target, anti-AD agent. In this study, we investigated the therapeutic ef...
关键词:DL0410 synapse plasticity NEUROTROPHY mitochondrial dynamics CREB 
Effects of mild hypothermia irrigation fluid on nerve function and oxidative stress during intracranial hematoma irrigation
《Journal of Hainan Medical University》2018年第22期34-38,共5页Tian-Guo Deng 
Objective: To study the effects of mild hypothermia irrigation fluid on nerve function and oxidative stress during intracranial hematoma irrigation. Methods: The patients with hypertensive cerebral hemorrhage who rece...
关键词:HYPERTENSIVE cerebral hemorrhage Mild HYPOTHERMIA IRRIGATION FLUID NERVE injury NEUROTROPHY Oxidative stress 
Correlation of serum uric acid level with neurotrophy, nerve injury and systemic oxidative stress response in patients with Parkinson's disease
《Journal of Hainan Medical University》2018年第20期25-28,共4页Hong-Ping Wu 
Objective:To investigate the correlation of serum uric acid level with neurotrophy, nerve injury and systemic oxidative stress response in patients with Parkinson's disease.Methods:A total of 60 patients with Parkinso...
关键词:Parkinson's disease Uric acid NEUROTROPHY NERVE injury OXIDATIVE stress 
Effect of Xinglou Chengqi Decoction on the blood brain barrier permeability, nerve damage and neurotrophy in rats with cerebral hemorrhage
《Journal of Hainan Medical University》2018年第15期5-9,共5页Miao Yu Xi-Yan Zhou Huan-Xin Cui 
Objective: To study the effect of Xinglou Chengqi Decoction on the blood brain barrier permeability, nerve damage and neurotrophy in rats with cerebral hemorrhage. Methods:Adult male SD rats were chosen as the experim...
关键词:CEREBRAL HEMORRHAGE Xinglou Chengqi DECOCTION Blood brain barrier Oxidative stress Inflammatory response CYTOKINE 
The effects of large doses of vitamin C and vitamin E on nerve injury, neurotrophic and oxidative stress in patients with acute craniocerebral injury被引量:4
《Journal of Acute Disease》2018年第2期69-73,共5页Cheng Zhang Jian-Ming Li Jun-Lin Hu Xia Zhou 
Objective:To study the effects of large doses of vitamin C and vitamin E on nerve injury,neurotrophic and oxidative stress in patients with acute craniocercbral injury.Methods:Patients with acute cranioccrebral trauma...
关键词:Acute CRANIOCEREBRAL injury OXIDATIVE stress VITAMIN C VITAMIN E NEUROTROPHY 
Effects of Urinary Kallidinogenase combined with mNGF on neurotrophic status, apoptosis and oxidative stress in patients with ischemic stroke
《Journal of Hainan Medical University》2018年第6期25-28,共4页Qing-Yan Wen Hao-Lin Ou Qiao-Song Sun 
Objective:To study the effects of Urinary Kallidinogenase combined with mouse nerve growth factor (mNGF) on neurotrophic status, apoptosis and oxidative stress in patients with ischemic stroke.Methods: Patients with a...
关键词:ISCHEMIC stroke URINARY Kallidinogenase Mouse NERVE growth factor NEUROTROPHY APOPTOSIS Oxidative stress 
Effects of lamotrigine + sodium valproate therapy on the nerve cell nutrition and apoptosis status as well as inflammatory response in patients with intractable epilepsy
《Journal of Hainan Medical University》2018年第1期149-152,共4页Wen Tang Mei-Mei Yang Ya-Ning Tang 
Objective: To investigate the effects of lamotrigine + sodium valproate therapy on the nerve cell nutrition and apoptosis as well as inflammatory response in patients with intractable epilepsy. Methods: A total of 70 ...
关键词:INTRACTABLE EPILEPSY LAMOTRIGINE Sodium valproate NEUROTROPHY APOPTOSIS Inflammatory response 
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