Supported by the Innovation Project of Jilin Academy of Agricultural Sciences(cxgc2017zy011);Major Project of Jilin Province Science and Technology Department(20170204046ny).
[Objectives]To explore the antidepressant-like effects of PAFL and its potential mechanisms.[Methods]This study used PAFL in mice under various conditions and analyzed the results.The antidepressant-like effects of fl...
The work was supported by the National Natural Science Foundation of China(No.81673911).
Objective:To study the effects of modified Wendan decoction on hippocampal neuron plasticity in a rat model of depression.Methods:Thirty-two rats were randomly divided into a blank control group,model group,traditiona...
This research was supported by National Natural Science Foundation of China(81673911).
Objective:To observe the effect of the modified Wendan decoction on the neurotrophic function of hippocampal astrocytes by regulating the tryptophan-kynurenine(TRP-KYN)neuroprotective metabolic pathway in depression-m...
The study was supported by the National Great Science Technology Projects(2014ZX09507003-002);the Drug Innovation Major Project(No.2018ZX09711001-003-002);the CAMS Initiative for Innovative Medicine(CAMS-IZM)(2016-IZM-3-007);the Beijing Natural Science Foundation(7192134,7204303);and the National Natural Science Foundation of China(81673480).
Alzheimer’s disease (AD) is a worldwide problem and there are no effective drugs for AD treatment. Previous studies show that DL0410 is a multi-target, anti-AD agent. In this study, we investigated the therapeutic ef...
Objective: To study the effects of mild hypothermia irrigation fluid on nerve function and oxidative stress during intracranial hematoma irrigation. Methods: The patients with hypertensive cerebral hemorrhage who rece...
Objective:To investigate the correlation of serum uric acid level with neurotrophy, nerve injury and systemic oxidative stress response in patients with Parkinson's disease.Methods:A total of 60 patients with Parkinso...
Objective: To study the effect of Xinglou Chengqi Decoction on the blood brain barrier permeability, nerve damage and neurotrophy in rats with cerebral hemorrhage. Methods:Adult male SD rats were chosen as the experim...
Objective:To study the effects of large doses of vitamin C and vitamin E on nerve injury,neurotrophic and oxidative stress in patients with acute craniocercbral injury.Methods:Patients with acute cranioccrebral trauma...
Objective:To study the effects of Urinary Kallidinogenase combined with mouse nerve growth factor (mNGF) on neurotrophic status, apoptosis and oxidative stress in patients with ischemic stroke.Methods: Patients with a...
Objective: To investigate the effects of lamotrigine + sodium valproate therapy on the nerve cell nutrition and apoptosis as well as inflammatory response in patients with intractable epilepsy. Methods: A total of 70 ...