B-CELLS

作品数:12被引量:47H指数:4
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相关领域:医药卫生更多>>
相关作者:刘鹏孙宁波许继田蒋仲敏更多>>
相关机构:河南医科大学胜利油田中心医院山东省千佛山医院泰山医学院更多>>
相关期刊:《Genes & Diseases》《国际肿瘤学杂志》《Neural Regeneration Research》《河南医学研究》更多>>
相关基金:国家自然科学基金山东省科技发展计划项目更多>>
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Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity
《Genes & Diseases》2022年第4期1049-1061,共13页Yi-Lin Chiu Yi-Ying Wu Robert B.Barndt Yu-Wen Lin Hou-Ping Sytwo Amy Cheng Kacy Yang Khee-Siang Chan Jehng-Kang Wang Michael D.Johnson Chen-Yong Lin 
This study was supported by Cancer Institute Grant R01 CA 123223(to MDJ and CYL);Grant(MAB-108-079)from the Ministry of Defense Medical Affairs Bureau;Grants(CMNDMC10705,CMNDMC10813)from Chi-Mei Medical Center(to J.-K.Wang);Grant(TSGH-E-109213-003)from Tri-Service General Hospital(to Y.-Y.Wu);Grants(108-2311-B-016-001-,109-2320-B-016-004-)from Ministry of Science and Technology(to Y.-L.Chiu).
The integral membrane,Kunitz-type serine protease inhibitors HAI-1 and HAI-2,can suppress the proteolytic activity of the type 2 transmembrane serine protease matriptase with high specificity and potency.High levels o...
关键词:HAI-1 HAI-2 MATRIPTASE Neoplastic B-cells Proteolytic activity 
Safety and Efficacy of a Proprietary Undenatured Beta-Glucan on Different Human Populations被引量:2
《Advances in Biological Chemistry》2022年第1期16-28,共13页Bjørn Kristiansen Ronald J. Amen 
After proving safety in animal and human models, a series of clinical trials were conducted to examine the administration of 1 mg/mL bid of an undenatured beta-glucan on the immune system;and on self-perceived effects...
关键词:Undenatured Beta-Glucan Quality-of Life Visual Analogue Scale (VAS) Lentinex® Fatigue Population B-CELLS 
The role of Epstein-Barr virus in multiple sclerosis:from molecular pathophysiology to in vivo imaging被引量:9
《Neural Regeneration Research》2019年第3期373-386,共14页Yi Guan Dejan Jakimovski Murali Ramanathan Bianca Weinstock-Guttman Robert Zivadinov 
Multiple sclerosis(MS) is a disease of the central nervous system characterized by inflammation, demyelination, and neuronal damage. Environmental and genetic factors are associated with the risk of developing MS, but...
关键词:EPSTEIN-BARR virus multiple SCLEROSIS MENINGEAL inflammation magnetic resonance imaging LEPTOMENINGEAL contrast enhancement MONONUCLEOSIS human endogeneous retrovirus-W B-CELLS 
BMI-1和 PADI4在食管鳞状细胞癌中的表达及其临床意义
《国际肿瘤学杂志》2016年第9期664-668,共5页季怀君 刘鹏 甄天昌 苏功章 孙宁波 蒋仲敏 
山东省科技发展计划(2013GSF11836)
目的:检测食管鳞状细胞癌组织及对应癌旁组织中肽酰基精氨酸脱亚胺酶4(PADI4)和B 细胞特异莫洛尼鼠白血病病毒整合位点-1(BMI-1)的表达,探讨其在食管鳞状细胞癌发生中的作用及临床意义,并探索两者的相关性。方法采用免疫组织化学...
关键词:食管肿瘤 肽酰基精氨酸脱亚胺酶4 B细胞特异莫洛尼鼠白血病病毒整合位点-1 Peptidylarginine deiminase 4 B-CELLS pecific Moloney leukemia virus insert site-1 
Intestinal antigen-presenting cells in mucosal immune homeostasis:Crosstalk between dendritic cells,macrophages and B-cells被引量:21
《World Journal of Gastroenterology》2014年第29期9653-9664,共12页Elizabeth R Mann Xuhang Li 
The intestinal immune system maintains a delicate balance between immunogenicity against invading pathogens and tolerance of the commensal microbiota. Inflammatory bowel disease (IBD) involves a breakdown in tolerance...
关键词:Antigen presenting cells Dendritic cells MACROPHAGES B cells Inflammatory bowel disease 
Impact of donor-specific antibodies on the outcomes of kidney graft:Pathophysiology, clinical, therapy被引量:6
《World Journal of Transplantation》2014年第1期1-17,共17页Maurizio Salvadori Elisabetta Bertoni 
Allo-antibodies, particularly when donor specific, are one of the most important factors that cause both early and late graft dysfunction. The authors review the current state of the art concerning this important issu...
关键词:Donor-specific antibodies SOLID-PHASE techniques COMPLEMENT activation Renal transplantation ANTIBODY-MEDIATED rejection DESENSITIZATION New drugs for B-CELLS 
B-cell Ligand Processing Pathways Detected by Large-scale Comparative Analysis
《Genomics, Proteomics & Bioinformatics》2012年第3期142-152,共11页Fadi Towfic Shakti Gupta Vasant Honavar Shankar Subramaniam 
funded by the National Science Foundation (NSF) Grant (DGE0504304) to Iowa State University and NSF Grants 0939370,0835541 and 0641037 awarded to SS
The initiation of B-cell ligand recognition is a critical step for the generation of an immune response against foreign bodies. We sought to identify the biochemical pathways involved in the B-cell ligand recognition ...
关键词:Ligand recognition B-CELLS Gene coexpression network alignment 
Expression of the B-Cell Lymphoma/Leukemia 11A Gene in Malignant Hematological Cell Lines through Quantitative Reverse Transcription Polymerase Chain Reaction
《Clinical oncology and cancer researeh》2011年第4期242-246,共5页Yang-jun GAO Don-g-mei HE Shao-hua CHEN Xiao-juan YAN Xiao-mao HU Yang-qiu LP 
The B-cell lymphoma/leukemia 11A (BCL11A) gene is essential for normal lymphoid development and has been associated with hematological malignancies. In the current study, the relative expression level of BCL11A in m...
关键词:B-cell lymphoma/leukemia 11A (BCL11A) malignantB-cells real-time quantitative reverse transcription-polymerasechain reaction. 
Different apoptotic reactions of dorsal root ganglion A- and B-cells after sciatic nerve axotomy: effect of p75 neurotrophin receptor被引量:2
《Chinese Medical Journal》2010年第19期2695-2700,共6页JIANG Yun Johannes Jakobsen 
Background By unbiased stereological methods, we have observed preferential dorsal root ganglion (DRG) B-cell loss in rodents after nerve injury, and caspase-3 activation and cell loss were related to the present of...
关键词:dorsal root ganglia APOPTOSIS p75 neurotrophin receptor AXOTOMY 
Value of the peripheral blood B-cells subsets in patients with ankylosing spondylitis被引量:7
《Chinese Medical Journal》2009年第15期1784-1789,共6页LIN Qu GU Jie-ruo LI Tian-wang ZHANG Fu-cheng LIN Zhi-ming LIAO Ze-tao WEI Qiu-jing CAO Shuang-yan LI Li 
This study was supported by the grants from the National Natural Science Foundation of China (No. 30325019, 30571735 and 30471611), Ministry of Health Key Clinical Project and Science Foundation of Guangdong Province of China (No. 2002Z3-E4021 and 2005A30801005).
Background The role of B-cell remains an enigma in the pathogenesis of ankylosing spondylitis (AS). This study aimed to investigate the distributions of B-cells and subsets in peripheral blood of AS patients and obs...
关键词:spondylitis  ankylosing B-lymphocyte subsets  etanercept 
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