BACKGROUND The microcystic,elongated,and fragmented(MELF)pattern of invasion in endometrioid endometrial carcinoma(EEC)is a special mode of myometrial invasion that has been recently recognized by the pathology commun...
funded by Guangzhou Scienceand Information Bureau Item of China(Grant No.201904010013);by Natural Science Foundation of Guangdong Province of China(Grant No.2018A0303130180).
Various therapeutic strategies have been developed to overcome ovarian cancer.However,the prognoses resulting from these strategies are still unclear.In the present work,we screened 54 small molecule compounds approve...
Objective:The present study was designed to evaluate the effects of adjuvant chemotherapy(CT)vs.radiotherapy(RT,alone or combined with CT)on the prognosis of patients with high-risk,early-stage(stage I and stage II)en...
supported by the National Natural Science Foundation of China(81972426 and 81874108);Special Projects for Strengthening Basic Research of Peking University(BMU2018JC005);National Key Technology R&D Program of China(2019YFC1005200 and 2019YFC1005201).
Background BRCA1/2 mutations have been shown to be associated with the development of many solid tumors including endometrial cancer(EC).The objectives of this study are to analyze the association between BRCA1/2 muta...
grants from the National Key Research and Development Program of China to CL(grant No.2018 YFC1004002);National Natural Science Foundation of China(grant Nos.81730071,81472734 and 81321003 to HZ and 81402388 to CR);Natural Science Foundation of Beijing Municipality(grant No.7162102 to YW and 7171005 to HZ);Ministry of Science and Technology of China(grant No.2016 YFC 1302103 to HZ);Leading Academic Discipline Project of Beijing Education Bureau(grant No.BMU 20110254 to CR);the 111 Project of the Ministry of Education,Peking University(grant No.BMU 2018 JC004 to HZ and BMU 20150492 to CR).
Objective:Lynch syndrome(LS)predisposes patients to early onset endometrioid endometrial cancer(EEC).However,little is known about LS-related EEC in the Chinese population.The aim of this study was to investigate the ...
Context: The prognostic significance of expression of V-Crk avian sarcoma virus CT10 oncogene homolog-like (CRKL) and Protein kinase CK2 β in endometroid carcinoma is not fully clarified. Aim: To assess the prognosti...
Objective: The aim was to detect the expression of PR and CD146 in paraf-fin-embedded tissue sections of endometrioid adenocarcinoma by using QDs double-labeling immunofluorescence, and evaluate the applied value of Q...
Supported by Financial support from the Fritz Bender Foundation(Munich,to Dascha Deutsch,Frank Entschladen and Kurt S Zanker);from the Nottingham University Hospital Trustees(contributed to the reagent costs)
AIM: To investigate the expression patterns of different adrenoceptor isoforms in ovarian cancer and their association with survival and tumor recurrence. METHODS: The protein expression levels of a1 B, a2 C and b2 ad...
Background Early stage (FIGO stage Ⅰ-Ⅱ) endometrioid endometrial adenocarcinoma (EEA) is very common in clinical practice.However,patients with the early stage EEA show various clinical behaviors due to biologic...
We report a very rare case of endometrioid adenocarcinoma arising from abdominal wall endometriosis in the appendectomy scar. A 47-year-old woman visited the surgical department, since she had a gradually growing and ...