RE-EPITHELIALIZATION

作品数：19被引量：80H指数：5
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相关领域：医药卫生更多>>
相关作者：滕艳侯宁鲁建云李志杰杨晓更多>>
相关机构：军事医学科学院中南大学湘雅三医院暨南大学更多>>
相关期刊：《Cancer Communications》《Bioactive Materials》《眼科学报》《Acta Biochimica et Biophysica Sinica》更多>>
相关基金：国家自然科学基金北京市自然科学基金广东省自然科学基金国家高技术研究发展计划更多>>
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Morroniside promotes skin wound re-epithelialization by facilitating epidermal stem cell proliferation through GLP-1R-mediated upregulation ofβ-catenin expression
《Acta Biochimica et Biophysica Sinica》2024年第7期1072-1084,共13页Chenghao Yu Siyuan Yu Zuohua Liu Lei Xu Zhiqiang Zhang Jiaming Wan Pengxiang Ji Ping Zhang Yi Fu Yingying Le Ruixing Hou 
supported by the grants from the Suzhou Science and Technology Development Plan(Nos.SKY2023107,and SKY2023108);the Suzhou Municipal Science and Technology Bureau(No.SKJY2021022).
Epidermal stem cells(EpSCs)play a vital role in skin wound healing through re-epithelialization.Identifying chemicals that can promote EpSC proliferation is helpful for treating skin wounds.This study investigates the...
关键词：MORRONISIDE wound healing epidermal stem cells cell proliferation glucagon-like peptide-1 receptor Β-CATENIN 
Angiopoietin-like 4 promotes epidermal stem cell proliferation and migration and contributes to cutaneous wound re-epithelialization被引量：1
《Acta Biochimica et Biophysica Sinica》2023年第8期1265-1274,共10页Yuan Yang Chenghao Yu Yingying Le Weijuan Gong Jihui Ju Guangliang Zhang Pengxiang Ji Rui Zuo Zhe Liu Ping Zhang Ruixing Hou Yi Fu 
supported by the grants from the Postgraduate Research and Practice Innovation Program of Jiangsu Province,China(No.KYCX21-3290);the Suzhou Medical and Health Science and Technology Innovation Project,Jiangsu Province,China(No.SKJY2021022,the General Program of Jiangsu Provincial Natural Science Foundation,China(No.BK20221245);the Key Medical Discipline of Suzhou City,Jiangsu Province,China(No.SZXK202127)。
Proliferation and migration of epidermal stem cells(EpSCs)are essential for epithelialization during skin wound healing.Angiopoietin-like 4(ANGPTL4)has been reported to play an important role in wound healing,but the ...
关键词：angiopoietin-like 4 cell migration cell proliferation epidermal stem cell wound healing 
The potential mechanisms of skin wound healing mediated by tetrapeptides from sea cucumber被引量：1
《Food Bioscience》2023年第3期2394-2405,共12页Zhihong Zheng Na Sun Zhiqiang Lu Jingru Zheng Simin Zhang Songyi Lin 
supported by the Science and Technology Innovation Foundation of Dalian City(grant numbers 2019J11CY005);Grad-uate Innovation Fund of Dalian Polytechnic University.
Numerous food-derived natural bioactive peptides have excellent skin wound healing potential.Herein,we re-ported the capacity of sea cucumber derived tetrapeptides VTPY and VLLY to promote wound healing.Our study reve...
关键词：Sea cucumber PEPTIDE Wound healing RE-EPITHELIALIZATION ANGIOGENESIS 
Role of defensins in diabetic wound healing
《World Journal of Diabetes》2022年第11期962-971,共10页Zhi-Xiang Tan Rui Tao Si-Cheng Li Bing-Zheng Shen Lan-Xia Meng Zhan-Yong Zhu 
Supported by the Scientific Research Project of Hubei Health Committee,No.WJ2021F106.
The adverse consequences resulting from diabetes are often presented as severe complications.Diabetic wounds are one of the most commonly occurring complications in diabetes,and the control and treatment of this is co...
关键词：DEFENSIN Diabetic wound Wound healing INFLAMMATION RE-EPITHELIALIZATION Tissue regeneration 
P311 promotes typeⅡtransforming growth factor-βreceptor mediated fibroblast activation and granulation tissue formation in wound healing被引量：2
《Burns & Trauma》2022年第1期175-190,共16页Jue Wang Ruoyu Shang Jiacai Yang Zhihui Liu Yunxia Chen Cheng Chen Wenxia Zheng Yuanyang Tang Xiaorong Zhang Xiaohong Hu Yong Huang Han-Ming Shen Gaoxing Luo Weifeng He 
National Natural Sciences Foundation of China(No.31872742 to W.F.H.and No.81630055 to G.X.L.);Military Medical Science and Technology Youth Training Program of Army Military Medical University(Third Military Medical University)(No.20QNPY024 to W.F.H.);the Special Project for Enhancing Science and Technology Innovation Ability(frontier exploration)of Army Military Medical University(Third Military Medical University)(No.2019XQY12 to W.F.H.).
Background:P311,a highly conserved 8 kDa intracellular protein,has recently been reported to play an important role in aggravating hypertrophic scaring by promoting the differentiation and secretion of fibroblasts.Nev...
关键词：P311 Wound healing FIBROBLASTS TGF-βRII-Smad pathway RE-EPITHELIALIZATION Granulation tissue formation Collagen deposition 
Bioactive glass promotes the barrier functional behaviors of keratinocytes and improves the Re-epithelialization in wound healing in diabetic rats被引量：5
《Bioactive Materials》2021年第10期3496-3506,共11页Fengling Tang Junliang Li Weihan Xie Yunfei Mo Lu Ouyang Fujian Zhao Xiaoling Fu Xiaofeng Chen 
This work was financially supported by the National Key R&D Program of China(2017YFC1105000);the National Natural Science Foundation of China(51672088,31971266,U1801252);the Key Research and Development Program of Guangzhou(202007020002);the Natural Science Foundation of Guangdong Province(2019A1515110480);the Science and Technology Program of Guangzhou(201804020060);Fundamental Research Funds for the Central Universities.
Upon skin injury,re-epithelialization must be triggered promptly to restore the integrity and barrier function of the epidermis.However,this process is often delayed or interrupted in chronic wounds like diabetic foot...
关键词：Bioactive glass KERATINOCYTE Barrier function Diabetic wound healing 
Calcium silicate accelerates cutaneous wound healing with enhanced re-epithelialization through EGF/EGFR/ERK-mediated promotion of epidermal stem cell functions被引量：5
《Burns & Trauma》2021年第1期184-195,共12页Bingmin Li Haowen Tang Xiaowei Bian Kui Ma Jiang Chang Xiaobing Fu Cuiping Zhang 
supported in part by the National Nature Science Foundation of China(81830064,81721092);the National Key ResearchDevelopment Plan(2017YFC1103304);the CAMS Innovation Fund for Medical Sciences(CIFMS,2019-I2M-5-059);the Military Medical Research and Development Projects(AWS17J005,2019-126);the Beijing Natural Science Foundation(7204309,7202197).
Background:Human epidermal stem cells(hESCs)play an important role in re-epithelialization and thereby in facilitating wound healing,while an effective way to activate hESCs remains to be explored.Calcium silicate(CS)...
关键词：BIOCERAMIC calcium silicate epidermal stem cells RE-EPITHELIALIZATION WOUNDS 
Obstruction of the formation of granulation tissue leads to delayed wound healing after scald burn injury in mice被引量：1
《Burns & Trauma》2021年第1期523-539,共17页Yunxia Chen Xiaorong Zhang Zhihui Liu Jiacai Yang Cheng Chen Jue Wang Zengjun Yang Lei He Pengcheng Xu Xiaohong Hu Gaoxing Luo Weifeng He 
Background:Delayed wound healing remains a common but challenging problem in patients with acute or chronic wound following accidental scald burn injury.However,the systematic and detailed evaluation of the scald burn...
关键词：Burn wound healing Second-degree deep scald Third-degree scald RE-EPITHELIALIZATION Granulation tissue Healing quality 
Photodynamic therapy accelerates skin wound healing through promoting re-epithelialization被引量：4
《Burns & Trauma》2021年第1期299-310,共12页Zengjun Yang Xiaohong Hu Lina Zhou Yaxiong He Xiaorong Zhang Jiacai Yang Zhenyu Ju Yih-Cherng Liou Han-Ming Shen Gaoxing Luo Michael R.Hamblin Weifeng He Rui Yin 
supported by National Natural Science Foundation of China(grant No.81571902,31872742).
Background:Epidermal stem cells(EpSCs)that reside in cutaneous hair follicles and the basal layer of the epidermis are indispensable for wound healing and skin homeostasis.Little is known about the effects of photoche...
关键词：Photodynamic therapy Wound healing 5-aminolevulinic acid RE-EPITHELIALIZATION Epidermal stem cells Transient amplifying cells 
Platelet-rich plasma accelerates skin wound healing by promoting re-epithelialization被引量：21
《Burns & Trauma》2020年第1期160-173,共14页Pengcheng Xu Yaguang Wu Lina Zhou Zengjun Yang Xiaorong Zhang Xiaohong Hu Jiacai Yang Mingying Wang Binjie Wang Gaoxing Luo Weifeng He Biao Cheng 
supported by the National Key Research and Development Plan of China(No.2017YFC1103301);Military Medical Innovation Special Projects(No.18CXZ029);National Natural Science Foundation of China(31872742);Top-notch Talent Training Plan(SWH2018BJKJ-04);MilitaryMedical Science and Technology Youth Training Plan(20QNPY024).
Background:Autologous platelet-rich plasma(PRP)has been suggested to be effective for wound healing.However,evidence for its use in patients with acute and chronic wounds remains insufficient.The aims of this study we...
关键词：Wound healing platelet-rich plasma INFLAMMATION RE-EPITHELIALIZATION ANGIOGENESIS Collagen deposition Epidermal stem cells 
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