BREAKPOINT

作品数：27被引量：42H指数：3
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相关领域：医药卫生更多>>
相关作者：赵越刘玉庆张怀强胡明高培基更多>>
相关机构：山东省畜禽疫病防治与繁育重点实验室山东大学广州医科大学中山大学更多>>
相关期刊：《Infectious Disease Modelling》《医学检验与临床》《Case Reports in Clinical Medicine》《World Journal of Gastrointestinal Surgery》更多>>
相关基金：国家自然科学基金山东省自然科学基金山东省优秀中青年科学家科研奖励基金国家教育部博士点基金更多>>
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Optimized protoplast isolation and transfection with a breakpoint:accelerating Cas9/sgRNA cleavage efficiency validation in monocot and dicot
《aBIOTECH》2024年第2期151-168,共18页Debasmita Panda Subhasis Karmakar Manaswini Dash Swagat Kumar Tripathy Priya Das Sagar Banerjee Yiping Qi Sanghamitra Samantaray Pradipta Kumar Mohapatra Mirza J.Baig Kutubuddin A.Molla 
support from the University Grant Commission(UGC);funding support from the Science and Engineering Research Board(SERB)-National Post-Doctoral Fellowship.;funding support from the Department of Biotechnology(DBT),Government of India-JRF program.MD,SB,MJB;funding from the Indian Council of Agricultural Research(ICAR),New Delhi,in the form of the Plan Scheme-‘Incentivizing Research in Agriculture’project;support from the Director,NRRI.
The CRISPR-Cas genome editing tools are revolutionizing agriculture and basic biology with their simplicity and precision ability to modify target genomic loci.Software-predicted guide RNAs(gRNAs)often fail to induce ...
关键词：PROTOPLAST Genome editing Transgene-free edited plants Rice CHICKPEA 
GAEP:a comprehensive genome assembly evaluating pipeline被引量：7
《Journal of Genetics and Genomics》2023年第10期747-754,共8页Yong Zhang Hong-Wei Lu Jue Ruan 
supported by the National Key Research and Development Project Program of China(2022YFC3400300,2019YFE0109600);the China Postdoctoral Science Foundation(2021M701584).
With the rapid development of sequencing technologies,especially the maturity of third-generation sequencing technologies,there has been a significant increase in the number and quality of published genome assemblies....
关键词：Genome assembly Assembly quality Assembly metrics Assembly evaluation pipeline Misassembly detection Misassembly breakpoint Assembly redundancy 
The Precipitation Concentration in the Cheliff Watershed,Algeria:A Critical Analysis for Sustainable Water Resource Management
《Chinese Journal of Urban and Environmental Studies》2023年第3期6-38,共33页Samiha BRAHIMI Hind MEDDI Mohamed MEDDI Faiza HALLOUZ Abdelamir SAAED HAMOUDI 
carried out within the framework of the SWATCH project(Prima project)funded by the DGRSDT,Algeria.
In this study,a statistical analysis of historical and projected values of the annual,seasonal,and supra-seasonal precipitation concentration index(PCI)was conducted for different stations in the Cheliff watershed.Sta...
关键词：PCI Cheliff trend analysis BREAKPOINT IDW climate projection scenarios. 
Research on Magnetically Coupled Resonant Detection Method for Breakpoint of Four Mesh Grounding Grid被引量：1
《CES Transactions on Electrical Machines and Systems》2023年第2期218-228,共11页Weihua Chen Shuai Wang Xiaoheng Yan Zhiquan Ye 
supported by the Science and Technology Research Innovation Team Project LT2019007 of the Department of Education of Liaoning Province;the Discipline Innovation Team Project LNTU20TD-02,29 of Liaoning Technical University。
Magnetically coupled resonant technology is a novel method for solving the breakpoint locating of power grounding grid.But the method can only detect breakpoints of a single mesh grounding grid at present.In this pape...
关键词：Grounding grid Magnetically coupled resonant detection Input impedance Phase frequency characteristic curve 
The malaria transmission in Anhui province China
《Infectious Disease Modelling》2023年第1期1-10,共10页Eric Kamana Di Bai Heidi E.Brown Jijun Zhao 
supported by the Natural Science Foundation of Shandong Province,China(ZR2018MH037).
Plasmodium vivax and Plasmodium falciparum cases have opposite trends in Anhui China in the past decade.Long term and seasonal trends in the transmission rate of P.falciparum in Africa has been well studied,however th...
关键词：BREAKPOINT Transmissionrate Biting rate SEASONALITY Climatic factors 
Combining gradual and abrupt analysis to detect variation of vegetation greenness on the loess areas of China
《Frontiers of Earth Science》2022年第2期368-380,共13页Panxing HE Zongjiu SUN Dongxiang XU Huixia LIU Rui YAO Jun MA 
This research was funded by the National Natural Science Foundation of China(Grant Nos.31760694 and 41601181).
The annual peak growth and trend shift of vegetation are critical in characterizing the carbon sequestration capacity of ecosystems.As the well-known area with the fastest vegetation growth in the world,the Loess Plat...
关键词：vegetation greenness gradual trend BREAKPOINT BFAST algorithm the Loess Plateau area 
Susceptibility breakpoint for cefquinome against Escherichia coli and Staphylococcus aureus from pigs被引量：3
《Journal of Integrative Agriculture》2021年第7期1921-1932,共12页ZHANG Hui-lin ZHAO Yi-yang ZHOU Zi-chong DING Huan-zhong 
supported by the National Natural Science Foundation of China(31972733)。
Cefquinome is the only fourth-generation cephalosporin used solely for veterinary applications.In this study,we established the wild-type cut-off(CO_(WT))and pharmacokinetic/pharmacodynamic cut-off(CO_(PD))of cefquino...
关键词：CEFQUINOME Escherichia coli Staphylococcus aureus CO_(WT) CO_(PD) 
Ewing sarcoma of the jejunum: A case report and literature review被引量：2
《World Journal of Gastrointestinal Surgery》2021年第5期507-515,共9页Kamleshsingh Shadhu Dadhija Ramlagun-Mungur Xiao-Chun Ping 
BACKGROUND Ewing sarcomas(ESs)are highly aggressive malignancy and are predominant in the long bones of extremities of children and young adults with a slight male predilection and rarely presents at extra skeletal lo...
关键词：Ewing sarcoma Small bowel Fluorescence in situ hybridization Ewing sarcoma breakpoint region 1 gene JEJUNUM Enterectomy Case report 
Chronic myeloid leukemia-from the Philadelphia chromosome to specific target drugs:A literature review被引量：3
《World Journal of Clinical Oncology》2021年第2期69-94,共26页Mariana Miranda Sampaio Maria Luísa Cordeiro Santos Hanna Santos Marques Vinícius Lima de Souza Gonçalves Glauber Rocha Lima Araújo Luana Weber Lopes Jonathan Santos Apolonio Camilo Santana Silva Luana Kauany de SáSantos Beatriz Rocha Cuzzuol Quézia Estéfani Silva Guimarães Mariana Novaes Santos Breno Bittencourt de Brito Filipe Antônio França da Silva Márcio Vasconcelos Oliveira Cláudio Lima Souza Fabrício Freire de Melo 
Chronic myeloid leukemia(CML)is a myeloproliferative neoplasm and was the first neoplastic disease associated with a well-defined genotypic anomaly―the presence of the Philadelphia chromosome.The advances in cytogene...
关键词：Chronic myeloid leukemia Breakpoint cluster region-Abelson murine leukemia IMMUNOTHERAPY Tyrosine kinase inhibitors Philadelphia chromosome Diagnosis 
Coexistence of breakpoint cluster region-Abelson1 rearrangement and Janus kinase 2 V617F mutation in chronic myeloid leukemia: A case report被引量：1
《World Journal of Clinical Cases》2019年第9期1087-1092,共6页Xue-Bing Shi Ji-Fa Jiang Feng-Xiang Jin Wei Cheng 
BACKGROUND The Janus kinase 2(JAK2) V617 F mutation is common in patients with breakpoint cluster region-Abelson1(BCR-ABL1)-negative myeloproliferative neoplasms,including polycythemia vera, essential thrombocythemia ...
关键词：Chronic MYELOID leukemia JAK2 V617F BCR-ABL1 IMATINIB MYELOPROLIFERATIVE neoplasm Case report 
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