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HLA-G 3’UTR 14 bp Insertion Is Associated with a Decreased Risk of Developing Human African Trypanosomiasis in the Côte d’Ivoire Population: 《Open Journal of Genetics》2019年第2期31-41,共11页Bernardin Ahouty Mathurin Koffi David Courtin Ilboudo Hamidou Didier Sokouri Innocent Abé Laure Gineau Thomas Konan Lingué Kouakou Tidou Abiba Sanogo Enock Matovu Bruno Bucheton Vincent Jamonneau Simon-Pierre N’Guetta; Human African trypanosomiasis (HAT), or sleeping sickness, caused by Trypanosoma brucei gambiense, is associated with diverse clinical outcomes. Host’s genetic factors involved in immunity are potential factors that ...; 关键词：HLA-G Human AFRICAN TRYPANOSOMIASIS TRYPANOSOMA BRUCEI gambiense Genetic Association Study

Evaluating the impact of targeting livestock for the prevention of human and animal trypanosomiasis,at village level,in districts newly affected with T.b.rhodesiense in Uganda: 《Infectious Diseases of Poverty》2017年第1期128-139,共12页Louise Hamill Kim Picozzi Jenna Fyfe Beatrix von Wissmann Sally Wastling Nicola Wardrop Richard Selby Christine Amongi Acup Kevin L.Bardosh Dennis Muhanguzi John D.Kabasa Charles Waiswa Susan C.Welburn; This study was funded with UK aid from the UK government’under the DfID Research into Use Programme(SCW,LH,KP,KP,KLB,CW,JDK)and from the European Union’s Seventh Framework Program(FP7/2007-2014)under grant agreement n°221948 Integrated Control of Neglected Zoonoses(ICONZ)(SCW,KP,KLB,CW,JDK);Treatment of village cattle was undertaken under the Stamp Out Sleeping Sickness Programme supported by IKARE and Ceva Sante Animale;The funders had no role in study design,data collection and analysis,decision to publish,or preparation of the manuscript.; Background:Uganda has suffered from a series of epidemics of Human African Trypanosomiasis(HAT),a tsetse transmitted disease,also known as sleeping sickness.The area affected by acute Trypanosoma brucei rhodesiense HA...; 关键词：African animal trypanosomiasis(AAT) Human African trypanosomiasis(HAT) Sleeping sickness Trypanosma brucei rhodesiense HAT(rHAT) Uganda T.b.brucei T.b.rhodesiense

Comparative analysis of chromosome segregation in human, yeasts and trypanosome: 《Frontiers in Biology》2014年第6期472-480,共9页Xianxian HAN Ziyin LI; Chromosome segregation is a tightly regulated process through which duplicated genetic materials are equally partitioned into daughter cells. During the past decades, tremendous efforts have been made to understand th...; 关键词：COHESIN SEPARASE SECURIN anaphase promoting complex spindle assembly checkpoint T^panosoma brucei

Coenzyme Q_(10) prevented full blown splenomegaly and decreased melarsoprol-induced reactive encephalopathy in mice infected with Trypanosoma brucei rhodesiense: 《Journal of Coastal Life Medicine》2014年第3期230-238,共9页James Nyabuga Nyariki John Kibuthu Thuita Grace Kemunto Nyambati Alfred Orina Isaac; Supported by a grant from graduate school(GSEU 20RR0234/2011),Egerton University Faculty Research Committee.; Objective:To establish the modulatory effects of coenzyme Q_(10)on experimental trypanosome infections in mice and evaluate the risk of occurrence and severity of melarsoprol-induced post treatment reactive encephalop...; 关键词：Trypanasoma brucei rhodesiense ENCEPHALOPATHY Coenzyme Q_(10) Melarsoprol Post treatment reactive encephalopathy SPLENOMEGALY

Effect of diminazene aceturate,levamisole and vitamin C combination therapy in rats experimentally infected with Trypanosoma brucei brucei被引量：3: 《Asian Pacific Journal of Tropical Medicine》2014年第6期438-445,共8页Adieme Ijeoma Chekwube Ezeh Ikenna Onyema Ugochukwu Emmanuel Ikenna Romanus Chukwuduruo Ezeokonkwo; Objective:To investigate the effect of diminazene aceturale(DA) alone or in combination with either levamisole and/or Vitamin C in albino rats experimentally infected with Trypanosoma brucei brucei.Methods:Thirty adul...; 关键词：DIMINAZENE aceturate LEVAMISOLE VITAMIN C Therapy TRYPANOSOMA BRUCEI BRUCEI RATS

Anti-trypanosomal effect of Peristrophe bicalyculata extract on Trypanosoma brucei brucei-infected rats被引量：1: 《Asian Pacific Journal of Tropical Biomedicine》2013年第7期523-531,共9页Abdulazeez Mansurah Abimbola Ibrahim Abdulrazak Baba Edibo Zakari Yenusa Sidali Joseph Omanibe Idris Habeeb Oladimeji; Supported by Education Trust Fund of Nigeria with the grant number ETF/DESS/AS&D/UNIV/ABU/ZARIA/V2; Objective:To investigate thein vitroandin vivoeffect of whole plant extracts ofPeristrophe bicalyculataonTrypanosoma brucei brucei-infected rats.Methods:The experiment wasdivided into two phases:In the first phase,the...; 关键词：Anti-trypanosomal activity TRYPANOSOMA BRUCEI BRUCEI Peristrophe bicalyculata LIPOPROTEINS

Antitrypanosomal potentials of the extract and fractions of Abrus precatorius seeds被引量：2: 《Asian Pacific Journal of Tropical Medicine》2012年第11期857-861,共5页Nwodo NJ Nwodo OFC; Objective:To evaluate the in vivo trypanocidal activity of the methanol extract and fractions of Abrus precatorius seeds in mice.Methods:Parasiteamia was induced unto mice by intraperitoneal injection of 1.25×10^...; 关键词：Abrus precatorius Seed EXTRACT Trypanocidal effect Parasiteamia FRACTIONS TRYPANOSOME BRUCEI BRUCEI Berenil

Experimental Trypanosoma brucei infection at immediate post partum period:effects on dam and the offspring: 《Asian Pacific Journal of Tropical Medicine》2010年第7期531-534,共4页Izuchukwu S Ochiogu Chukwuka N Uchendu John I Ihedioha; Objective:To investigate the effects of immediate post-partum infection with Trypanosoma brucei（T.brucei） on dam and offspring.Methods:Sixty female Albino rats（Rattus norvegicus） weighing between 130-170 g were us...; 关键词：TRYPANOSOMA BRUCEI POST-PARTUM INFECTION Litter Parasitaemia.

Human African trypanosomiasis in endemic focus of Abraka,Nigeria: 《Asian Pacific Journal of Tropical Medicine》2010年第6期448-450,共3页Onyebiguwa Patrick Goddey Nmorsi Clement Isaac Igho Benjamin Igbinosa Duncan Ogheneocovo Umukoro Dafe Palmer Aitaikuru; Objective:To investigated the prevalence of human African trypanosomiasis(HAT),a neglected tropical disease caused by Trypanosoma brucei gambiens in an endemic focus of Nigeria,as it relates to age,sex and occupationa...; 关键词：Human African TRYPANOSOMIASIS TRYPANOSOMA BRUCEI gambiense SEROPOSITIVITY Risk factors NIGERIA

NUCLEOTIDE SEQUENCES OF THE 5′ TERMINAL REGIONS OF L-rRNA FROM Trypanosoma evansi AND T. brucei AND COMPARATIVE ANALYSIS OF D2 DOMAINS被引量：1: 《Chinese Science Bulletin》1991年第1期61-65,共5页屈良鹄余小强伦照荣; Project supported by the National Natural Science Foundation of China.; Ⅰ. INTRODUCTIONTrypanosoma evansi has the widest geographic range of all the pathogenic trypanosomes and is an important etiological agent of disease in the domestic animals, especially in buffalo and horse in China....; 关键词：TRYPANOSOMA L-rRNA¹) NUCLEOTIDE sequence PHYLOGENY DNA probe.

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