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CHECKPOINT: 作品数：720被引量：1395H指数：15; 导出分析报告; 相关领域：医药卫生自动化与计算机技术更多>>; 相关作者：段红刘穆进张彩田志刚景年财更多>>; 相关机构：上海大学华中科技大学国防科学技术大学CheckPoint软件技术有限公司更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金中国博士后科学基金广东省自然科学基金国家重点基础研究发展计划更多>>

Crosstalk between cell fate and survival pathways during uterine cervical carcinoma progression: a molecular and clinical perspective: 《Journal of Cancer Metastasis and Treatment》2023年第1期75-93,共19页Sudip Samadder Palash Paul Arpan De; The development of uterine cervical cancer is primarily attributed to infection by high-risk human papillomaviruses(HR-HPVs).E5,E6 and E7,the three early oncoproteins of HR-HPVs,have been implicated in initiation and ...; 关键词：Uterine cervical cancer HEDGEHOG Notch Wnt G1/S checkpoint GSK3Β β-catenin MYC

Treatment strategy after the discontinuation of immunotherapy for head and neck cancer: a review: 《Journal of Cancer Metastasis and Treatment》2023年第1期210-220,共11页Tetsuro Wakasugi; First-line systemic therapy with immune checkpoint inhibitors(ICIs)is currently the mainstream treatment for recurrent or metastatic squamous cell carcinoma of the head and neck(R/M SCCHN)that is not amenable to local...; 关键词：Immune checkpoint inhibitors squamous cell carcinoma head and neck

The role of modern immunotherapy in metastatic urothelial cancer:mini review: 《Journal of Cancer Metastasis and Treatment》2022年第1期150-159,共10页Francesca Jackson-Spence Charlotte Toms Yu-Hsuen Yang Leo Jurascheck Julia Choy Lucy Flanders Bernadett Szabados Thomas Powles; The approval of immune checkpoint inhibitors(ICIs)has changed the treatment landscape in many aspects of urothelial cancer(UC),in both non-muscle-invasive bladder cancer and muscle-invasive bladder cancer and has intr...; 关键词：Metastatic urothelial cancer bladder cancer immune therapy immune checkpoint inhibitors biomarkers

Immunotherapy in malignant pleural mesothelioma:a long story ended in success: 《Journal of Cancer Metastasis and Treatment》2022年第1期102-113,共12页Alberto Bongiovanni Antonio Frassoldati Luana Calabrò; Malignant pleural mesothelioma(MPM)is an aggressive and rare disease,mainly due to asbestos exposure,characterized by a poor prognosis.For almost two decades,platinum-based chemotherapy has been the only approved ther...; 关键词：Malignant pleural mesothelioma IMMUNOTHERAPY immune checkpoint inhibitors cancer vaccine

The role of VISTA in the tumor microenvironment: 《Journal of Cancer Metastasis and Treatment》2022年第1期365-378,共14页Dina Rabadi Alia A.Sajani Randolph J.Noelle J.Louise Lines; Research was supported by NIH grants R01AR070760 and R01CA214062(Randolph J.Noelle).; V-domain Ig Suppressor of T cell Activation(VISTA)is a negative immune checkpoint that is expressed on multiple immune cell subsets and has been characterized in T cells,macrophages,and myeloid-derived suppressor cell...; 关键词：VISTA CANCER MDSC immune checkpoint

The role of immune checkpoint inhibitors in triple-negative breast cancer: recent developments and future perspectives: 《Journal of Cancer Metastasis and Treatment》2021年第1期837-878,共42页Marios Papadimitriou Zoi Liakouli Christos A.Papadimitriou; Triple-negative breast cancer(TNBC)represents the subtype of breast cancer with the most aggressive biological behavior and the worst prognosis compared to other breast cancers.Metastatic TNBC is characterized by a hi...; 关键词：Triple-negative breast cancer immune checkpoint inhibition CTLA-4 PD-1 PD-L1

Recent advances in the frontline treatment of metastatic renal cell carcinoma: 《Journal of Cancer Metastasis and Treatment》2021年第1期695-706,共12页Camillo Porta Mimma Rizzo; We aim to describe the most recent advances in the upfront treatment of metastatic renal cell carcinoma,and to provide criteria-though often subjective-which could be used for treatment selection,by means of a critica...; 关键词：Renal cell carcinoma immune checkpoint inhibitors antiangiogenics SURVIVAL

Immuno-oncology in triple-negative breast cancer: 《Journal of Cancer Metastasis and Treatment》2021年第1期133-144,共12页Anne-Sophie Heimes Marcus Schmidt; The immune system plays an important role in breast cancer.Triple-negative breast cancer(TNBC)has a higher mutational load compared to other subtypes.In addition,higher levels of tumor-associated antigens suggests tha...; 关键词：Tumor infiltrating lymphocytes cancer-immunity-cycle immune checkpoint inhibitors vaccination tumor-associated antigens neoantigens

Development of a Functional Assessment of Chronic Illness Therapy item library and primary symptom list for the assessment of patient-reported adverse events associated with immune checkpoint modulators: 《Journal of Cancer Metastasis and Treatment》2020年第1期74-87,共14页Kimberly A.Webster Mary L.O’Connor Aaron R.Hansen Sheetal Kircher Heather S.L.Jim Adam P.Dicker Monika Janda Kari Ala-leppilampi Clifton O.Bingham III Josephine Feliciano Norah Lynn Henry Laurie E.Steffen McLouth David Cella; Laurie E.Steffen McLouth was supported by NCI R25 CA122061(PI:Avis);Adam P.Dicker received additional support from the National Cancer Institute,the Prostate Cancer Research Program(Dept.of Defense);the American Society of Radiation Oncology,the American Society of Clinical Oncology,NRG Oncology,and the Prostate Cancer Foundation;Josephine Feliciano received additional support from Bristol Myers Squibb and Astra Zeneca.; Aim:To develop a comprehensive item library of patient-reported,immunotherapy-related adverse events(irAEs)that draws from and expands on the Functional Assessment of Chronic Illness Therapy(FACIT)Measurement System.M...; 关键词：Immunotherapy immune checkpoint modulators quality of life immune-related adverse events patient reported outcomes cancer ONCOLOGY

Novel immunotherapeutic approaches in head and neck cancer被引量：1: 《Journal of Cancer Metastasis and Treatment》2019年第11期36-46,共11页Molly E.Heft Neal Catherine T.Haring Jacqueline E.Mann J.Chad Brenner Matthew E.Spector Paul L.Swiecicki; Heft Neal ME was supported in part by the NIH Grant(T32 DC005356).Brenner JC was supported in part by American Cancer Society Grant:132034-RSG-18-062-01-TBG.Brenner JC was supported by F31:DE-027600-01; Unresectable recurrent or metastatic head and neck cancer is an incurable disease with survival of approximately 12 months. Head and neck tumors exhibit numerous derangements in the tumor microenvironment that aid in ...; 关键词：IMMUNOTHERAPY head and neck immune evasion immune derangement checkpoint inhibitors recurrent/metastatic

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