INCRETIN

作品数:27被引量:110H指数:6
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相关领域:医药卫生更多>>
相关作者:陈家伦陈重更多>>
相关机构:中山大学上海交通大学医学院附属瑞金医院云南中医药大学南京医科大学更多>>
相关期刊:《Chinese Medical Journal》《Signal Transduction and Targeted Therapy》《World Journal of Diabetes》《World Journal of Methodology》更多>>
相关基金:国家自然科学基金更多>>
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Potassium voltage-gated channel subfamily H member 2(KCNH2)is a promising target for incretin secretagogue therapies
《Signal Transduction and Targeted Therapy》2024年第9期4079-4090,共12页Ying-Chao Yuan Hao Wang Ze-Ju Jiang Chang Liu Qi Li Si-Rui Zhou Jin-Kui Yang 
supported by grants from the National Natural Science Foundation of China(81930019)to Jin-Kui Yang;supported by grants from Beijing Municipal Natural Science Foundation(7232232)to Hao Wang。
Derived from enteroendocrine cells(EECs),glucagon-like peptide-1(GLP-1)and glucose-dependent insulinotropic peptide(GIP)are pivotal incretin hormones crucial for blood glucose regulation.Medications of GLP-1 analogs a...
关键词:KCNH2 POTASSIUM elevated 
Glucagon-like peptide 1 receptor agonist:A potential game changer for cholangiocarcinoma
《World Journal of Gastroenterology》2024年第34期3862-3867,共6页Ronnakrit Trakoonsenathong Ching-Feng Chiu Charupong Saengboonmee 
Supported by Mekong-Lancang Cooperation Special Fund;Cho-Kalaphruek Excellent Research Project for Medical Students;The International Internship Pilot Program,No.IIPP2023283.
Glucagon-like peptide-1 receptor(GLP-1R)agonist,a subgroup of incretin-based anti-diabetic therapies,is an emerging medication with benefits in reducing blood glucose and weight and increasing cardiovascular protectio...
关键词:CARCINOGENESIS CHOLANGIOCARCINOMA Diabetes mellitus INCRETIN Glucagon-like peptide 1 receptor 
Role of incretins and glucagon receptor agonists in metabolic dysfunction-associated steatotic liver disease:Opportunities and challenges
《World Journal of Hepatology》2024年第5期731-750,共20页Chencheng Xie Naim Alkhouri Mohamed A Elfeki 
Metabolic dysfunction-associated steatotic liver disease(MASLD)has become the most common chronic liver disease worldwide,paralleling the rising pandemic of obesity and type 2 diabetes.Due to the growing global health...
关键词:Metabolic dysfunction-associated steatotic liver disease Metabolic dysfunction-associated steatohepatitis Glucagon-like peptide-1 Glucose-dependent inulinotropic polypeptide GLUCAGON INCRETIN Receptor agonist 
Rikkunshito increases peripheral incretin-hormone levels in humans and rats
《World Journal of Methodology》2024年第1期102-113,共12页Hiroshi Kono Shinji Furuya Hidenori Akaike Katsutoshi Shoda Yoshihiko Kawaguchi Hidetake Amemiya Hiromichi Kawaida Daisuke Ichikawa 
BACKGROUND It was reported that rikkunshito(TJ-43)improved the cisplatin-induced decreases in the active form of ghrelin in plasma;however,other effects on gastrointestinal hormones have not been investigated.AIM To i...
关键词:Incretin hormone Japanese traditional herbal medicine Gastric inhibitory polypeptide Glucagon-like polypeptide-1 Islet cells INSULIN 
Incretin-FGF21 fusion molecule maximizes metabolic effects in mice
《Acta Biochimica et Biophysica Sinica》2024年第1期144-147,共4页Yulin Kong Shenglong Zhu Yong Q.Chen 
Common metabolic diseases,such as obesity and nonalcoholic steatohepatitis(NASH),are major public health concerns.The only therapeutic approach that offers weight loss of 20%or more is bariatric surgery.Medications ar...
关键词:DISEASES SURGERY OBESITY 
Opportunities and challenges of incretin-based hypoglycemic agents treating type 2 diabetes mellitus from the perspective of physiological disposition被引量:3
《Acta Pharmaceutica Sinica B》2023年第6期2383-2402,共20页Yaochen Xie Qian Zhou Qiaojun He Xiaoyi Wang Jincheng Wang 
supported by the National Natural Science Foundation of China (No. 82003873 and 81903708);the Postdoctoral Science Foundation of China (No. 2020M681899);the Fundamental Research Funds for the Central Universities (No. 2021QNA7019)。
The treatment of patients with diabetes mellitus, which is characterized by defective insulin secretion and/or the inability of tissues to respond to insulin, has been studied for decades. Many studies have focused on...
关键词:T2DM Incretins-based hypoglycemic agents GLP-1 receptor agonists DPP-4 inhibitors Physiological disposition Metabolism EXCRETION Drug drug interactions 
Diabetes and fatty liver:Involvement of incretin and its benefit for fatty liver management被引量:1
《World Journal of Diabetes》2023年第5期549-559,共11页I Dewa Nyoman Wibawa I Ketut Mariadi Gde Somayana Cokorda Istri Yuliandari Krisnawardani Kumbara Dwijo Anargha Sindhughosa 
Fatty liver disease is defined as liver condition characterized by hepatic steatosis,closely related to pathological conditions in type 2 diabetes and obesity.The high prevalence of fatty liver disease in obese patien...
关键词:Fatty liver DIABETES INCRETIN Insulin resistance 
Rikkunshito increases appetite by enhancing gastrointestinal and incretin hormone levels in patients who underwent pyloruspreserving pancreaticoduodenectomy: A retrospective study
《World Journal of Gastrointestinal Surgery》2023年第5期871-881,共11页Hiroshi Kono Naohiro Hosomura Hidetake Amemiya Katsutoshi Shoda Shinji Furuya Hidenori Akaike Yoshihiko Kawaguchi Hiromichi Kawaida Daisuke Ichikawa 
BACKGROUND Rikkunshito(TJ-43)relieves gastrointestinal disturbance by increases in the levels of acylated ghrelin.AIM To investigate the effects of TJ-43 in patients undergoing pancreatic surgery.METHODS Forty-one pat...
关键词:Gastrointestinal hormone Japanese traditional herbal medicine GHRELIN INCRETIN Pancreatic surgery 
Benefit-risk assessment of incretin and other anti-diabetic agents in type 2 diabetes using a stochastic multicriteria acceptability analysis model
《Chinese Medical Journal》2023年第1期102-104,共3页Sanbao Chai Shuqing Yu Fengqi Liu Zuoxiang Liu Qingqing Yang Feng Sun 
National Natural Science Foundation of China(No.72074011)
To the Editor:Incretin-based therapies for type 2 diabetes mellitus(T2DM)include incretin mimetics of glucagonlike peptide-1 receptor agonists(GLP-1 RAs)and incretin enhancers of dipeptidyl peptidase-4(DPP-4)inhibitor...
关键词:DRUGS T2DM diabetes 
Incretin based therapy and pancreatic cancer:Realising the reality被引量:1
《World Journal of Gastroenterology》2022年第25期2881-2889,共9页Varun Suryadevara Ayan Roy Jayaprakash Sahoo Sadishkumar Kamalanathan Dukhabandhu Naik Pazhanivel Mohan Raja Kalayarasan 
Incretin-based therapies like glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors help maintain the glycaemic control in patients with type 2 diabetes mellitus with additional systemic bene...
关键词:Diabetes mellitus Dipeptidyl peptidase-4 inhibitor Glucagon-like peptide-1 receptor agonist INCRETIN PANCREATITIS Pancreatic Cancer 
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