云南高校图书馆联盟文献共享服务平台- HETEROZYGOTE

HETEROZYGOTE: 作品数：11被引量：17H指数：2; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：韦文惠更多>>; 相关机构：柳州职业技术学院更多>>; 相关期刊：《World Journal of Pediatrics》《Natural Science》《Journal of Cancer Therapy》《Acta Pharmacologica Sinica》更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划广西教育厅科研项目广西高校优秀人才计划项目更多>>

Liver-specific glucocorticoid action in alcoholic liver disease:Study of glucocorticoid receptor knockout and knockin mice: 《Liver Research》2024年第2期91-104,共14页Yazheng Wang Conor Fahy Hong Lu; supported by the National Institutes of Health(grant R21AA027349).; Background and aim:Glucocorticoids are the only first-line drugs for severe alcoholic hepatitis(AH),with limited efficacy and various side effects on extrahepatic tissues.Liver-targeting glucocorticoid therapy may hav...; 关键词：Glucocorticoid receptor(GR) Alcohol-associated steatosis(AS) Alcoholic hepatitis(AH) HETEROZYGOTE Liver-specific knockout Liver-specific knockin Hepatic protection

Mapping and genetic validation of a grain size QTL qGS7.1 in rice(Oryza sativa L.)被引量：3: 《Journal of Integrative Agriculture》2019年第8期1838-1850,共13页XUE Pao ZHANG Ying-xin LOU Xiang-yang ZHU Ai-ke CHEN Yu-yu SUN Bin YU Ping CHENG Shi-hua CAO Li-yong ZHAN Xiao-deng; supported by grants from the National Key Research and Development Program of China (2018YFD0100806);the Zhejiang Provincial Natural Science Foundation of China (LY18C130008);the National Natural Science Foundation of China (31521064);the Major Project of the Genetically Modified and National Key Transgenic Research Projects, China (2016ZX08001-002);the Super Rice Breeding Innovation Team and Rice Heterosis Mechanism Research Innovation Team of the Chinese Academy of Agricultural Sciences Innovation Project (CAASASTIP-2013-CNRRI); Grain size is a major determinant of grain weight, which is one of the components of rice yield. The objective o this study was to identify novel, and important quantitative trait loci(QTLs) for grain size and weight ...; 关键词：RICE (Oryza sativa L.) quantitative TRAIT LOCI GRAIN size GRAIN weight residual HETEROZYGOTE

Validation of qGSIO, a quantitative trait locus for grain size on the long arm of chromosome 10 in rice (Oryza sativa L.)被引量：7: 《Journal of Integrative Agriculture》2017年第1期16-26,共11页WANG Zhen CHEN Jun-yu ZHU Yu-jun FAN Ye-yang ZHUANG Jie-yun; supported by the National Natural Science Foundation of China (31521064);the Chinese 863 Program (2014AA10A603);project of the China National Rice Research Institute (2014RG003-1); Grain size is a major determinant of grain weight and a trait having important impact on grain quality in rice. The objective of this study is to detect QTLs for grain size in rice and identify important QTLs that hav...; 关键词：grain size quantitative trait locus residual heterozygote rice （Oryza sativa L.）

Lemierre's syndrome with double heterozygote status in the methylenetetrahydrofolate reductase gene: 《World Journal of Pediatrics》2014年第3期281-283,共3页Mostafa Behpour-Oskooee Abdollah Karimi Shirin Sayyahfar; Background:There are some risk factors being more vulnerable to Lemierre's syndrome such as a hypercoagulable state.Methods:We report a rare case of Lemierre's syndrome with ethmoid and maxillary sinusitis,bilateral m...; 关键词：Lemierre's syndrome MASTOIDITIS methylenetetrahydrofolate reductase sigmoid sinus thrombosis

Can a polymorphism in the thalassemia gene and a heterozygote CFTR mutation cause acute pancreatitis?被引量：2: 《World Journal of Clinical Cases》2014年第3期62-66,共5页J-Matthias L?hr Stephan Haas; The case of a 32-year-old black woman of African descent who suffered from repeated episodes of acute pancreatitis, initially triggered when flying on airplanes, is reported. She did not drink alcohol or smoke. Geneti...; 关键词：Acute pancreatitis Hypoxia Flying THALASSEMIA HEMOGLOBIN CYSTIC fibrosis TRANSMEMBRANE conductance regulator HEREDITARY persistence of fetal HEMOGLOBIN

The PARP-1 Inhibitor Olaparib Causes Retention of γ-H2AX Foci in <i>BRCA</i>1 Heterozygote Cells Following Exposure to Gamma Radiation: 《Journal of Cancer Therapy》2013年第11期44-52,共9页Emma C. Bourton Piers N. Plowman Amanda J. Harvey Sheba Adam Zahir Christopher N. Parris; A novel treatment for cancer patients with homozygous deletions of BRCA1 and BRCA2 is to use drugs that inhibit the enzyme poly(ADP-ribose) polymerase (PARP). Specific inhibition of PARP-1 can induce synthetic lethali...; 关键词：BRCA1 BRCA2 HETEROZYGOTE Radiosensitivity PARP INHIBITOR Gamma-H2AX Imaging Flow Cytometry

Modelling of the populating development of the genome in the radiation condition of the environment被引量：2: 《Natural Science》2011年第12期1029-1033,共5页Andrey N. Volobuev Eugene S. Petrov; The existence of the genome population in condition of radiation environment has been considered. The differences between the laws of the allele frequencies for autosomal genes and genes linked to sex are described. R...; 关键词：Population Ionizing Radiation GENOTYPES Frequency of ALLELE RECESSIVE ALLELE HETEROZYGOTE HARDY-WEINBERG Equilibrium INBREEDING

Accumulation of Mutant Genes and Its Pathway with Reproductive Isolation被引量：1: 《Agricultural Science & Technology》2010年第3期4-6,46,共4页韦文惠; Supported by Research Projects from Education Department of Guangxi(200807MS065);Mathematical Modeling in Population Genetics from Talents Scheme of Universities in Guangxi~~; According to the fitness of heterozygote was lower than homozygote among panmictic population,the process of generational accumulate of mutant gene r was considered.Branch point of r＇s frequency by generational evolu...; 关键词：Reproductive isolation FITNESS Mutant gene HETEROZYGOTE Branch point

Dynamic behavior of fragile X full mutations in cultured female fetal fibroblasts: 《Acta Pharmacologica Sinica》2004年第7期973-976,共4页Yu-jieSUN XiaoHAN; AIM: To assess mitotic stability of the fragile X full mutations and itsrelationship with DNA methylation. METHODS: The length change of the expanded CGG repeats wasexamined and correlated it with the methylation stat...; 关键词：DNA FEMALE FETUS FIBROBLASTS fragile X syndrome HETEROZYGOTE human mutation X chromosome

Relationship　between　loss　of　heterozygosity　of　microsatellite　on　DCC　gene　and　prognosis　of　colorectal　adenocarcinoma被引量：2: 《World Journal of Gastroenterology》1997年第2期64-65,共2页ZHAO Po 1, HU Ying Chuan 2, WANG De Wen 3, WANG Zhi Ping 3, XU Xin Zhao 4, YI Ping Yong 2, GAO Ya Bing 3 and YANG Guang Hua 2; AIM To investigate the relationship between the loss of heterozygosity (LOH) of microsatellite on the Deleted in colorectal carcinoma (DCC) gene and the prognosis of colorectal adenocarcinoma. METHODS A retrospecti...; 关键词：COLORECTAL neoplasms polymerase chain reaction ONCOGENES ADENOCARCINOMA HETEROZYGOTE PROGNOSIS

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