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A New Taxoid from Leaves and Branches of Taxus chinensis: 《Chinese Chemical Letters》2004年第3期307-308,共2页FuShengWANG LiYanPENG YuZHAO QinShiZHAO KunGU HanDongSUN; A new taxoid, 2-deacetyl-2a, 14b-dihydroxybaccatin IV (1), was isolated from the leaves and branches of Taxus chinensis together with the known compound baccatin IV (2). The structure of the new compound was elucidat...; 关键词：TAXOIDS Taxus chinensis 2-deacetyl-2a 14b-dihydroxy-baccatin IV.

Synthesis of Novel Thiol Taxoid Based on the 7,10-Di-(2,2,2-trichloroethyl-oxycarbonyl)-10-deacetylbaccatin Ⅲ and (4R,5S)-2,4-Diphenyl-2-oxazoline-5-carboxylic acid: (2'R,3'R)-10-Deacetyl- 2'-deoxy-mercaptopaclitaxel: 《有机化学》2004年第z1期57-58,共2页XU,Li QI,Xin ZHOU,Zhi-Ping; 　　The complex natural product paclitaxel (TaxolR) 1, first isolated from Taxus brevifolia, and its semisynthetic analog,docetaxel 2, represent a large family of taxane diterpenoids, which revealed excellent clinical...

Structure identification for compound I separated and purified from taxoids-produced endophytic fungi (Alternaria. alternata var. taxi 1011): 《Journal of Forestry Research》2003年第3期217-220,共4页项勇刘君呂安国崔京霞; Endophytic fungi are widely found in almost all kinds of plants. Many endophytic fungi can produce some physio-logical active compounds, which are same to or analog to those isolated from their hosts. Producing physio...; 关键词：Alternaria. Alternata var. taxi 1011 TAXOIDS Separation Purification Structure identification

A New Taxane Diterpenoid from the Seeds of Taxus yunnanensis被引量：1: 《Chinese Chemical Letters》2000年第3期235-238,共4页Qing Wen SHI Takayuki ORITANI Ding ZHAO; described here comes from the Ministry of Education, Science;ports, and Culture of japan through a grant-in-aid for scientifi; A new taxane diterpenoid with a rearranged 5/7/6-membered ring system was isolated from the seeds of the Chinese pew, Taxus yunnanensis. Its structure was established as 9 alpha-acetoxy-5 alpha-cinnamoy]-11(15 --> 1)-...; 关键词：Taxus yunnanensis TAXOID ISOLATION TAXUS

Microbial Transformation of Taxoids and Synthesis of Taxoids with an Oxetane Ring被引量：1: 《Chinese Chemical Letters》1998年第1期39-43,共5页Shang Hut HU Xu Fang TIAN Wen Yi HE Man KONG Di An SUN Qi Cheng FANG(Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050); Microbial trdrisformation of taxoids was inveStigared: taxoid 2 was transformed into 1β and 14β hydroxylated derivahves 3 and 4, unnatural taxoid 6 was transformed into 1β-hydroxy derivative 7 and 11(15-1) abeotaxa...; 关键词：TAXOID abeotaxane oxetane ring chemoenzymatic method

Two New Taxane Diterpenoids from Taxus Chinensis被引量：1: 《Chinese Chemical Letters》1998年第1期45-49,共5页Liang, JY Huang, KS Gunatilaka, AAL Yang, L; Two new taxane diterpenoids, 2-deacetoxy-7,9-dideacetyltaxinine J (1) and 2-deacetoxytaxinine B (3), were isolated from the barks of Taxus chinensis. Their structures were elucidated by spectroscopic methods.; 关键词：TAXANE DITERPENOID deacetoxy-taxinine TAXOID SEMISYNTHESIS

A New Taxoid from Microbial Transformation: 《Chinese Chemical Letters》1997年第12期0-0,共2页Hong XU Ke Di CHENG Wei Shuo FANG Ping ZHU Chao MENG(Key Laboratory of Biosynthesis of Natural Products, Ministry of Public Health)(Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050); A new taxoid taxa-4(20), 11-diene-2α, 5β, 10β, 14β-tetraol-2α, 14β-diacetate (sinenxan H) (1) was obtained by biotransformation of taxa-4(20), 11-diene-2α, 5α, 10β, 14β-tetraol-2α, 5α, 10β, 14β-tetraacet...; 关键词：PPM A New Taxoid from Microbial Transformation

A New Taxoid from the Needles of Taxus × media Hicksii: 《Chinese Chemical Letters》1997年第12期0-0,共2页Yong Li GAO Jin Yun ZHOU Yi Ding and Qi Cheng FANG(Institute of Matcria Medica, Chinese Academy of Medical Sciences and Peking Union Medital College Beijing 100050); A new taxoid with 5/716 taxane skeleton, named taxamedin A (1) was isolated from the needles of Taxus x media Hicksii. Its structure was elucidated by spectal analysis; 关键词：A New Taxoid from the Needles of Taxus

Study on 3D Quantitative Structure-Activity Relationships of Taxoid被引量：1: 《Chinese Chemical Letters》1997年第10期893-896,共4页Zhu, QQ Guo, ZR Huang, N Wang, MM Chu, FM; A series of 94 taxol analogues exhibiting antitumor activity were investigated using comparative molecular field analysis (CoMFA) method. The most optimal CoMFA from 80 compounds selected randomly yielded a two-compon...

Chemistry of Taxoid Sinenxan A: (Ⅰ) Epimerization of the 14β-hydroxyl Group: 《Chinese Chemical Letters》1997年第4期277-280,共4页Guang Yan HUANG Ji Yu GUO Xiao Tian LIANG(Institute of Materia Medica, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100050); Compound 2 with 14β-hydroxyl group was successfully converted into its epimerized α-counterpart via oxidation - reduction.The elimination product (6) was auto-oxidized to epoxide 8,even in the solid state; 关键词：CL Epimerization of the 14 hydroxyl Group Chemistry of Taxoid Sinenxan A

TAXOID