LAMELLIPODIA

作品数：4被引量：8H指数：2
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相关领域：医药卫生生物学更多>>
相关期刊：《Mechanobiology in Medicine》《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《Neuroscience Bulletin》更多>>
相关基金：国家自然科学基金更多>>
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Isotoosendanin inhibits triple-negative breast cancer metastasis by reducing mitochondrial fission and lamellipodia formation regulated by the Smad2/3-GOT2-MYH9 signaling axis
《Acta Pharmacologica Sinica》2024年第12期2672-2683,共12页Jing-nan Zhang Ze Zhang Zhen-lin Huang Qian Guo Ze-qi Wu Chuang Ke Bin Lu Zheng-tao Wang Li-li Ji 
supported by the"Young Qihuang Scholar"for Li-li Ji,National Natural Science Foundation of China(82273994);Program of Shanghai Academic Research Leader(23XD1404000);the Organizational Key Research and Development Program of Shanghai University of Traditional Chinese Medicine(2023YZZ02).
Triple-negative breast cancer(TNBC)is incurable and prone to widespread metastasis.Therefore,identification of key targets for TNBC progression is urgently needed.Our previous study revealed that isotoosendanin(ITSN)r...
关键词：TNBC isotoosendanin GOT2 MYH9 DRP1 mitochondrial fission 
Probing the protrusions:lamellipodia and filopodia in cancer invasion and beyond
《Mechanobiology in Medicine》2024年第2期7-13,共7页Laras Pratiwi Elisa Elisa Henry Sutanto 
The dynamic protrusions of lamellipodia and filopodia have emerged as crucial players in tumor progression and metastasis.These membrane structures,governed by intricate actin cytoskeletal rearrangements,facilitate ca...
关键词：LAMELLIPODIA FILOPODIA Cancer invasion METASTASIS MECHANOBIOLOGY 
P-Rex1 Overexpression Results in Aberrant Neuronal Polarity and Psychosis-Related Behaviors被引量：2
《Neuroscience Bulletin》2019年第6期1011-1023,共13页Qiongwei Li Lifang Wang Yuanlin Ma Weihua Yue Dai Zhang Jun Li 
supported by grants from the National Natural Science Foundation of China (81730037, 81871077, and 81671363);the Beijing Municipal Science and Technology Project (Z181100001518001);the Young Elite Scientists Sponsorship Program By China Association for Science and Technology (YESS20160068)
Neuronal polarity is involved in multiple developmental stages, including cortical neuron migration,multipolar-to-bipolar transition, axon initiation, apical/basal dendrite differentiation, and spine formation. All of...
关键词：P-Rex1 NEURODEVELOPMENT Polarity LAMELLIPODIA Psychosis-related behavior 
Atomic force microscopy imaging of live mammalian cells被引量：6
《Science China(Life Sciences)》2013年第9期811-817,共7页LI Mi LIU LianQing XI Ning WANG YueChao DONG ZaiLi XIAO XiuBin ZHANG WeiJing 
supported by the National Natural Science Foundation of China (61175103);CAS FEA International Partnership Program for Creative Research Teams
Atomic force microscopy (AFM) was used to examine the morphology of live mammalian adherent and suspended cells. Time-lapse AFM was used to record the locomotion dynamics of MCF-7 and Neuro-2a cells. When a MCF-7 cell...
关键词：atomic force microscopy cell locomotion LAMELLIPODIA CYTOSKELETON POLYDIMETHYLSILOXANE 
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