FLIM

作品数：28被引量：42H指数：3
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Introduction to the Special Issue on Fluorescence Lifetime Imaging Microscopy(FLIM)
《Journal of Innovative Optical Health Sciences》2019年第5期1-2,共2页Junle Qu Liwei Liu 
Fluorescence Lifetime Imaging Microscopy(FLIM)is an advanced tool that enables the description of exponential decay rate distribution of fuorescent molecules in the samples.This technique has been broadly used in biom...
关键词：FLUORESCENCE EXPONENTIAL enable 
Fast fluorescence lifetime imaging techniques:A review on challenge and development被引量：2
《Journal of Innovative Optical Health Sciences》2019年第5期3-29,共27页Xiongbo Liu Danying Lin Wolfgang Becker Jingjing Niu Bin Yu Liwei Liu Junle Qu 
support from the National Key R&D Program of China(2017YFA0700500);National Natural Science Foundation of China(61775144/61525503/61620106016/61835009/81727804);(Key)Project of Department of Education of Guangdong Province(2015KGJHZ002/2016KCXTD007);Guangdong Natural Science Foundation(2014A030312008,2017A030310132,2018A030313362);Shenzhen Basic Research Project(JCYJ20170818144012025/JCYJ20170818141701667/JCYJ20170412105003520/JCYJ20150930104948169).
Fluorescence lifetime imaging microscopy(FLIM)is increasingly used in biomedicine,material science,chemistry,and other related research fields,because of its advantages of high specificity and sensitivity in monitorin...
关键词：Fluorescence lifetime imaging microscopy(FLIM) acquisitin time imaging speed dead time photon fficiency time domain frequency domain scanning wide-field imaging time-correlated single photon counting(TCSPC) gated detection gated image intensifer modulated inage intensifier SPAD array detector 
Implementation and application of FRET-FLIM technology被引量：2
《Journal of Innovative Optical Health Sciences》2019年第5期57-68,共12页Shiqi Wang Binglin Shen Sheng Ren Yihua Zhao Silu Zhang Junle Qu Liwei Liu 
supported by the National Natural Science Foundation of China(61722508/61525503/61620106016/81727804);The National Key Research and Development Program of China(2017YFA0700402);Guangdong Natural Science Foundation Innovation Team(2014A030312008);Shenzhen Basic Research Project(JCYJ20150930104948169/JCYJ20160328144746940/GJHZ20160226202139185/JCYJ20170412105003520)。
With the development of the new detection methods and the function of fluorescent molecule,researchers hope to further explore the internal mechanisms of organisms,monitor changes in the intracellular microenvironment...
关键词：Fluorescence resonance energy transfer fuorescenc-lifetime imaging microscopy protein-protein interaction 
Fluorescence life-time imaging microscopy(FLIM)monitors tumor cell death triggered by photothermal therapy with MoS_(2) nanosheets被引量：1
《Journal of Innovative Optical Health Sciences》2019年第5期69-78,共10页Hongda Liang Zheng Peng Xiao Peng Yufeng Yuan Teng Ma Yiwan Song Jun Song Junle Qu 
supported by the National Key R&D Program of China(2018YFC0910602);the National Natural Science Foundation of China(Grant Nos.31771584/61775145/61605121,61620106016/61525503/61835009/81727804);Guangdong Natural Science Foundation Innovation Team(2014A030312008);Shenzhen Basic Research Project(JCYJ20170818100153423/JCYJ20170412110212234/JCYJ20160328144746940/JCYJ20170412105003520/JCYJ20170302142902581);Science Foundation of SZU(Grant No.000193).
Recently,photothermal therapy(PTT)has been proved to have great potential in tumor therapy.In the last several years,MoS_(2),as one novel member of nanomaterials,has been applied into PTT due to its excellent photothe...
关键词：Fluorescence lifetime imaging microscopy(FLIM) MoS_(2)nanosheets photothermal therapy(PTT) 4T1 cells 
Green emitted CdSe@ZnS quantum dots for FLIM and STED imaging applications
《Journal of Innovative Optical Health Sciences》2019年第5期79-85,共7页Mengjie Zhao Shuai Ye Xiao Peng Jun Song Junle Qu 
supported by the National Key R&D Program of China(2018YFC0910600);the National Natural Science Foundation of China(61605124/41603059/61525503/61620106016/61835009/81727804);Project of Department of Education of Guangdong Province(2015KGJHZ002/2016KCXTD007);Guangdong Natural Science Foundation Innovation Team(2014A030312008);Shenzhen Basic Research Project(JCYJ20150930104948169/JCYJ20160328144746940/JCYJ20170412105003520);the Natural Science Foundation of Shenzhen University(2019108).
Inorganic quantum dots(QDs)have excellent optical properties,such as high°uorescence intensity,excellent photostability and tunable emission wavelength,etc.,facilitating them to be used as labels and probes for bioim...
关键词：CdSe@ZnS QDs FLIM STED living cells 
An automated multiwell plate reading flim microscope for live cell autofluorescence lifetime assays
《Journal of Innovative Optical Health Sciences》2014年第5期99-113,共15页Douglas J.Kelly Sean C.Warren Sunil Kumar Joao L.Lagarto Benjamin T.Dyer Anca Margineanu Eric W.-F.Lam Chris Dunsby Paul M.W.French 
funding from the UK Biotechnology and Biological Sciences Research Council(BBSRCBB/H00713X/1);the UK Engineering and PhysicalSciences Research Council(EPSRC EP/IO2770X/1);the UK Technology Strategy Board Technology Award(CHBT/007/00030,EP/C54269X,inpartnership with Astra Zeneca,GE Healthcare,GSK,Kentech Instruments Ltd).
Fluorescence lifetime imaging(FLIM)is increasingly used to read out cellular autofluorescenceoriginating from the coenzyme NADH in the context of investigating cell metabolic state.Wepresent here an automated multiwel...
关键词：High content analysis FLIM NADH METABOLISM cisplatin. 
Deep tissue imaging by enhanced photon collection
《Journal of Innovative Optical Health Sciences》2014年第5期136-144,共9页Viera Crosignani Sohail Jahid Alexander Dvornikov Enrico Gratton 
Funding was provided by National Institutes of Health P50 GM076516;by the National Center for Research Resources(5P41RR003155-27);the National Instit ute of General Medical Sciences(8 P41GM103540-27).
We have developed a two-photon fluorescence microscope capable of imaging up to 4mm inturbid media with micron resolution.The key feature of this instrument is the innovative de-tector,capable of collecting emission p...
关键词：Deep tissue microscopy fluorescence SHG FLIM 
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