云南高校图书馆联盟文献共享服务平台- FLIM

FLIM: 作品数：28被引量：42H指数：3; 导出分析报告; 相关作者：屈军乐牛憨笨郭宝平林丹樱刘娟更多>>; 相关机构：深圳大学中国科学院山西农业大学安徽大学更多>>; 相关期刊：《Nano-Micro Letters》《Chinese Optics Letters》《光谱学与光谱分析》《Science Bulletin》更多>>; 相关基金：国家自然科学基金广东省自然科学基金中国检验检疫科学研究院基本科研业务费专项资金中国科学院“百人计划”更多>>

Exploring the interplay between zinc-induced protein dyshomeostasis and mitochondrial dysfunction using viscositysensitive sensor: 《Smart Molecules》2024年第4期205-214,共10页Xuan He Jiaqi Li Wenye He Jia Zhai Yu Wei Xin Zhang Baoxing Shen He Huang; support from the Qinglan Project of Jiangsu Province of China,National Natural Science Foundation of China(Grant No.22007048);the Natural Science Foundation of Jiangsu Basic Research Program(BK20221324).; Mitochondria are crucial sites for protein quality control within cells.When mitochondrial stress is triggered by protein misfolding,it can accelerate abnormal protein aggregation,potentially inducing various diseases...; 关键词：FLIM mitochondrial damage protein aggregates viscosity sensitivity Zn2þdetection

Evaluating the tumor stratification with a lysosomal pH sensitive-probe by fluorescence lifetime imaging被引量：1: 《Chinese Chemical Letters》2024年第3期262-267,共6页Jun Yan Xing Liang Qian Zhang Luolin Wang Weiying Lin; financially supported by the National Natural Science Foundation of China(Nos.21877048,22077048 and 22277014);Guangxi Natural Science Foundation(Nos.2021GXNSFDA075003,AD21220061);the Startup Fund of Guangxi University(No.A3040051003)。; Owing to the anaerobic metabolism in the tumor,abundant acidic metabolites are produced and accumulated in the cells.Therefore,the cells in different tumor layers are directly linked to the pH micro-environment.Nevert...; 关键词：FLIM pH Fluorescence imaging LYSOSOME Tumor imaging

Performance Improvement of CIGS Solar Cell: A Simulation Approach by SCAPS-1D: 《Energy and Power Engineering》2023年第8期291-306,共16页Md. Ferdous Wahid Md. Nuralam Howlader Nazmul Ahasan Md. Mizanur Rahman; Thin-film solar cells possess the distinct advantage of being cost-effective and relatively simple to manufacture. Nevertheless, it is of utmost importance to enhance their overall performance. In this research work, ...; 关键词：Thin-Flim CIGS-Based Solar Cell Non-Toxic Solar Cell SCAPS-1D Numerical Simulation Renewable Energy

基于FLIM-FRET技术揭示OVCAR-3细胞膜和BSA-DOX纳米颗粒的相互作用被引量：2: 《中国激光》2023年第3期130-140,共11页李慧娴林方睿徐云剑李艳萍王柯欣王诗琪邹炎华胡睿屈军乐刘丽炜; 国家自然科学基金(62175163,62225505,61935012);深圳市杰青项目(RCJC20210706091949022);深圳市重点项目(JCYJ20200109105404067)。; 荧光寿命显微成像(FLIM)常用来检测活细胞内荧光基团的寿命信息,以实现微观定量分析。荧光共振能量转移(FRET)可用来表征能量从供体荧光分子到受体荧光分子的传递过程。将FLIM技术与FRET结合(FLIMFRET),可以监测活细胞中蛋白质的相互作...; 关键词：生物光学荧光共振能量转移荧光寿命细胞膜

Forthrightly monitoring ferroptosis induced by endoplasmic reticulum stresses through fluorescence lifetime imaging of microviscosity increases with a specific rotor: 《Chinese Chemical Letters》2022年第5期2537-2540,共4页Chuanhao Liu Lin Zhou Lijuan Xie Ying Zheng Huizi Man Yi Xiao; supported by the National Natural Science Foundation of China(Nos.21776037,22174009);Dalian Sci-ence and Technology Innovation Fund(No.2020JJ25CY014);Quanzhou Science and Technology Plan Project(No.2019C033R).; To test the hypothesis that the microviscosity changes of Endoplasmic Reticulum(ER)can be a useful indicator of ferroptosis promoted by ER Stresses(ERS),a new ER targeting viscosity rotor,L-Vis-1 was developed and app...; 关键词：Ferroptosis VISCOSITY FLIM ERS ROTOR

FLIM as a Promising Tool for Cancer Diagnosis and Treatment Monitoring被引量：1: 《Nano-Micro Letters》2021年第9期48-74,共27页Yuzhen Ouyang Yanping Liu Zhiming MWang Zongwen Liu Minghua Wu; This work was partially supported by the National Natural Science Foundation of China(Grant No.61775241);the Hunan Science Fund for Distinguished Young Scholar(2020JJ2059);Youth Innovation Team(Grant No.2019012)of CSU,Hunan province key research and development project(Grant No.2019GK2233,Grant 2020SK2053);Hunan Province Graduate Research and Innovation Project(Grant No.CX20190177);the Science and Technology Innovation Basic Research Project of Shenzhen(Grant No.JCYJ20180307151237242);Also,YPL acknowledges the support by the Project of State Key Laboratory of High-Performance Complex Manufacturing,Central South University(Grant No.ZZYJKT2020-12).Besides,we acknowledge the art work from Servier Medical Art.Y.Z.O and Y.P.L contributed equally to this work.; Fluorescence lifetime imaging microscopy(FLIM)has been rapidly developed over the past 30 years and widely applied in biomedical engineering.Recent progress in fluorophore-dyed probe design has widened the application...; 关键词：Fluorescence lifetime imaging microscopy Förster resonance energy transfer Reduced form of nicotinamide adenine dinucleotide Biosensors CANCER

Assessing chromatin condensation for epigenetics with a DNA-targeting sensor by FRET and FLIM techniques: 《Chinese Chemical Letters》2021年第8期2395-2399,共5页Xinfu Zhang Lu Wang Ning Li Yi Xiao; supported by the National Natural Science Foundation of China (Nos.21421005,21576040,21776037,21901031 and 22078047);Science and Technology Foundation of Liaoning Province (No.2020-YQ-08);Dalian Science and Technology Innovation Fund (No.2020JJ25CY014);the Fundamental Research Funds for the Central Universities (Nos.DUT18RC(3)027 and DUT20RC(5)024)。; Here we propose a fluorescent sensor,Chroma-V,consisted of a Hoechst ligand(Hoe) to target chromatin DNA and a BODIPY rotor(BDP) to sense the local viscosity that reflects chromatin condensation state.Within Chroma-V,...; 关键词：Ratio imaging Fluorescence lifetime imaging EPIGENETIC CHROMATIN BODIPY rotor Hoechst

荧光共振能量转移-荧光寿命显微成像(FRET-FLIM)技术在生命科学研究中的应用进展被引量：5: 《光谱学与光谱分析》2021年第4期1023-1031,共9页罗淋淋牛敬敬莫蓓莘林丹樱刘琳; 国家重点研发计划项目(2016YFD0101803);广东省创新创业团队项目(2014ZT05S078);广东省基础与应用研究基金项目(2019A1515011222);深圳市基础研究面上项目(JCYJ20190808112207542)资助。; 细胞是动植物结构和生命活动的基本单位。细胞过程的一个重要特点就是其生化组分在时空调控上的相互作用关系。然而,利用传统的生化方法(如酵母双杂交系统、pull-down系统等)很难在空间上评估活细胞内分子间的相互作用。光学技术的快速...; 关键词：荧光共振能量转移荧光寿命显微成像蛋白相互作用疾病诊断

Layer-dependent signatures for exciton dynamics in monolayer and multilayer WSe2 revealed by fluorescence lifetime imaging measurement: 《Nano Research》2020年第3期661-666,共6页Yuanshuang Liu Huanglong Li Cuicui Qiu Xiangmin Hu Dameng Liu; This work is supported by the National Natural Science Foundation of China(Nos.51527901,51575298,51705285,and 11890672);And we are grateful to Tsinghua-Nikon Imaging Core Facility for providing technical support and to Yanli Zhang for assistance with confocal microscopy and image processing.; Two-dimensional(2D)transition-metal dichalcogenide(TMD)materials have aroused noticeable interest due to their distinguished electronic and optical properties.However,little is known about their complex exciton proper...; 关键词：two-dimensional(2D)WSe2 exciton dynamics fluorescence lifetime fluorescence lifetime imaging microscopy(FLIM) density functional theory(DFT)

基于多光子激光扫描技术的人体皮肤黑色素含量和分布的在体探究被引量：3: 《香料香精化妆品》2020年第1期71-74,85,共5页苏宁刘红梅胡楠庞建平杨丽雷芳敏刘娟; 中国检验检疫科学研究院基本科研业务费专项（2017JK013）;中国检验检疫科学研究院基本科研业务费专项（2018JK040）; 采用多光子激光扫描技术(MPT)和荧光寿命成像技术(FLIM),通过荧光图像和FLIM图像可视化,以及荧光信号强度和短寿命组分a1的计算,对不同光暴露区域皮肤表皮层黑色素的含量和分布进行定性和定量在体探究。试验结果表明:皮肤表皮浅层中黑...; 关键词：多光子激光扫描(MPT) 荧光寿命成像(FLIM) 黑色素在体定量检测

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