Supported by Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI),the Ministry of Health&Welfare,Republic of Korea (No. HF20C0121);Shanxi Key Laboratory of Tradition Herbal Medicines Processing (No. 20210901);the Innovation Team of Shanxi University of Chinese Medicine (No. 2022TD1014)
Objective:To investigate the effects of Clean-DM1(C-DM1),a polyherbal formulation of Radix Scrophulariae,Radix Astragali,Rhizoma Atractylodis,and Radix Salviae Miltiorrhizae,on high-fat diet(HFD)-induced diabetes mice...
Supported by the Chinese Medicine Research Project of Hubei Provincial Health Commission(No.ZY2019Q024);Scientific Research Project of Wuhan Municipal Health Commission(No.WX20B11);Scientific Research Project of Wuhan Municipal Health Commission(No.WZ20C01)。
Objective To investigate the effect of emodin on high glucose(HG)-induced podocyte apoptosis and whether the potential anti-apoptotic mechanism of emodin is related to induction of adenosine-monophosphate-activated pr...
supported by the General Project of Shaanxi Science and Technology Plan(No.2021JM-472);the Key Laboratory Project of Education Department of Shaanxi Province(Nos.21JS014 and 21JS007);the Subject Innovation Team of Shaanxi University of Chinese Medicine(No.2019YL14);the Postgraduate Student’s Innovation Project of Shaanxi University of Chinese Medicine(No.2021-09),China。
Objective:To determine the potential molecular mechanisms underlying the therapeutic effect of curcumin on hepatocellular carcinoma(HCC)by network pharmacology and experimental in vitro validation.Methods:The predicti...
Supported by National Natural Science Foundation of China: Study on the Clinical Comparison of Basic and Clinical Based on Chip Technology for the Precision Treatment of Diabetic Large Vascular Disease with Danzhi Jiangtang Capsule (No. 81774286)。
OBJECTIVE: To observe the therapeutic effect of Shenzhu Tiaopi granule(参术调脾颗粒, STG) on insulin resistance(IR) in the liver of diabetic Goto-Kakizaki(GK) rat and investigate underlying mechanisms.METHODS: Ten 12-...
Supported by the National Natural Science Foundation of China(No.81473639);the Fundamental Research Funds for the Central Universities(No.3332018037)
Diabetic peripheral neuropathy(DPN) is a progressive neurodegenerative disease of peripheral nervous system with high energy requirement. The adenosine monophosphate-activated protein kinase(AMPK)/peroxisome prolifera...
[Objectives] This study aimed to study the absorption of curcumin monophosphate, a derivative of curcumin, in the small intestine of rats. [Methods] In situ recirculation perfusion technique was used to study the abso...
Supported by the National Natural Science Foundation of China:Study of Influence of Supplementing Qi and Activating Blood Circulation Herbs on Microvascular Dysfunction and Related Regulators of Myocardial Infarction Rats(No.81173142);Study of Influence of Supplementing Qi and Activating Blood Circulation Herbs on Mitochondrial Energy Metabolism and Signal Transduction of Myocardial Ischemia Rats(No.81473552);The Basic Research Program(graduate program)of Beijing university of Chinese Medicine:Study of Influence of Supplementing Qi and Activating Blood Circulation Herbs on Notch Signal Network of Myocardial Infarction Rats(No.2016-JYB-XS034)
OBJECTIVE: To investigate the effect of Yiqihuoxue prescription(YQHX) from Traditional Chinese Medicine(TCM) on myocardial glucose and lipid metabolism after myocardial infarction via the cross talk between the liver ...
Advancing age and increased lifespan of human populations worldwide in the mid-nineteenth century,have led to a significant increase in the incidence of neurodegenerative diseases one of the major cause of disability ...
Supported by the National Natural Science Foundation of China(No.81173179);the Natural Science Foundation of Fujian Province(No.2011J01198);the Fujian Medical Innovation Project(No.2009-CX-19);the Research Foundation of Fujian Health Department(No.Zlcnfm02);the Fujian Provincial Department of Education Category A Projects(No.JA09131);the Fujian Health Department of Traditional Chinese Medicine Research(No.WZY0920);the CHEN Ke-ji Integrative Medicine Development Fund(No.CKJ2008047,CKJ2009004);the Integrative Medicine of Fujian Key Laboratory of Age-related Diseases Funded Projects(No.2008J1004-10)
Objective:To investigate the effect of Dan-gua Fang(丹瓜方) on adenosine 5’-monophosphate(AMP) activated protein kinase(AMPK) α expression in liver and subsequent improvement of glucose and lipid metabolism.M...