MONOPHOSPHATE

作品数:92被引量:261H指数:8
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相关领域:医药卫生更多>>
相关作者:肖明芳应汉杰杨晓亮吕浩何明芳更多>>
相关机构:南京工业大学南京大学福建中医药大学中国人民解放军第一军医大学更多>>
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相关基金:国家自然科学基金福建省自然科学基金国家重点基础研究发展计划广东省自然科学基金更多>>
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  • 学科=医药卫生—中药学x
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Clean-DM1, a Korean Polyherbal Formula, Improves High Fat Diet-Induced Diabetic Symptoms in Mice by Regulating IRS/PI3K/AKT and AMPK Expressionsin Pancreas and Liver Tissues
《Chinese Journal of Integrative Medicine》2024年第2期125-134,共10页Piao Wang Yi Liu Seok Yong Kang Chenzi Lyu Xiang Han Tianjun Ho Kyung Jae Lee Xianglong Meng Yong-Ki Park Hyo Won Jung 
Supported by Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI),the Ministry of Health&Welfare,Republic of Korea (No. HF20C0121);Shanxi Key Laboratory of Tradition Herbal Medicines Processing (No. 20210901);the Innovation Team of Shanxi University of Chinese Medicine (No. 2022TD1014)
Objective:To investigate the effects of Clean-DM1(C-DM1),a polyherbal formulation of Radix Scrophulariae,Radix Astragali,Rhizoma Atractylodis,and Radix Salviae Miltiorrhizae,on high-fat diet(HFD)-induced diabetes mice...
关键词:high-fat diet type 2 diabetes mellitus herbal formulation insulin receptor substrate/phosphatidylinositol 3 kinase/protein kinase B adenosine 5'-monophosphate-activated protein kinase network pharmacology high performance liquid chromatography-mass spectrometry analysis 
Emodin Ameliorates High Glucose-Induced Podocyte Apoptosis via Regulating AMPK/mTOR-Mediated Autophagy Signaling Pathway被引量:3
《Chinese Journal of Integrative Medicine》2023年第9期801-808,共8页LIU Hong CHEN Wei-dong HU Yang-lin YANG Wen-qiang HU Tao-tao WANG Huan-lan ZHANG Yan-min 
Supported by the Chinese Medicine Research Project of Hubei Provincial Health Commission(No.ZY2019Q024);Scientific Research Project of Wuhan Municipal Health Commission(No.WX20B11);Scientific Research Project of Wuhan Municipal Health Commission(No.WZ20C01)。
Objective To investigate the effect of emodin on high glucose(HG)-induced podocyte apoptosis and whether the potential anti-apoptotic mechanism of emodin is related to induction of adenosine-monophosphate-activated pr...
关键词:EMODIN diabetic nephropathy AUTOPHAGY podocyte apoptosis adenosine-monophosphate-activated protein kinase/mammalian target of rapamycin signaling pathways 
Investigation and experimental validation of curcumin-related mechanisms against hepatocellular carcinoma based on network pharmacology被引量:4
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2022年第8期682-698,共17页Yang CHEN Qian LI Sisi REN Ting CHEN Bingtao ZHAI Jiangxue CHENG Xiaoyan SHI Liang SONG Yu FAN Dongyan GUO 
supported by the General Project of Shaanxi Science and Technology Plan(No.2021JM-472);the Key Laboratory Project of Education Department of Shaanxi Province(Nos.21JS014 and 21JS007);the Subject Innovation Team of Shaanxi University of Chinese Medicine(No.2019YL14);the Postgraduate Student’s Innovation Project of Shaanxi University of Chinese Medicine(No.2021-09),China。
Objective:To determine the potential molecular mechanisms underlying the therapeutic effect of curcumin on hepatocellular carcinoma(HCC)by network pharmacology and experimental in vitro validation.Methods:The predicti...
关键词:CURCUMIN Network pharmacology p53 Adenosine 5’-monophosphate(AMP)-activated protein kinase(AMPK) Apoptosis AUTOPHAGY 
Effect of Shenzhu Tiaopi granule(参术调脾颗粒) on hepatic insulin resistance in diabetic Goto-Kakizakirats via liver kinase B1/adenosine 5’-monophosphate/mammalian target of rapamycin signaling pathway被引量:2
《Journal of Traditional Chinese Medicine》2021年第1期107-116,共10页YIN Yundong WU Yuanyuan YOU Liangzhen FANG Zhaohui 
Supported by National Natural Science Foundation of China: Study on the Clinical Comparison of Basic and Clinical Based on Chip Technology for the Precision Treatment of Diabetic Large Vascular Disease with Danzhi Jiangtang Capsule (No. 81774286)。
OBJECTIVE: To observe the therapeutic effect of Shenzhu Tiaopi granule(参术调脾颗粒, STG) on insulin resistance(IR) in the liver of diabetic Goto-Kakizaki(GK) rat and investigate underlying mechanisms.METHODS: Ten 12-...
关键词:Diabetes mellitus insulin resistance insulin receptor substrate proteins TOR serine-threonine kinases Shenzhu Tiaopi granule 
Effects of Mitochondrial Dysfunction via AMPK/PGC-1α Signal Pathway on Pathogenic Mechanism of Diabetic Peripheral Neuropathy and the Protective Effects of Chinese Medicine被引量:25
《Chinese Journal of Integrative Medicine》2019年第5期386-394,共9页ZHANG Qian LIANG Xiao-chun 
Supported by the National Natural Science Foundation of China(No.81473639);the Fundamental Research Funds for the Central Universities(No.3332018037)
Diabetic peripheral neuropathy(DPN) is a progressive neurodegenerative disease of peripheral nervous system with high energy requirement. The adenosine monophosphate-activated protein kinase(AMPK)/peroxisome prolifera...
关键词:monophosphate-activated protein kinase PEROXISOME proliferator-activated receptor-γ COACTIVATOR  SIRTUINS diabetic peripheral NEUROPATHY Chinese medicine 
Absorption of Curcumin Monophosphate in Rat Intestinal Circulation
《Medicinal Plant》2019年第1期66-68,73,共4页Yu WANG Luyang DING Longru SUN 
[Objectives] This study aimed to study the absorption of curcumin monophosphate, a derivative of curcumin, in the small intestine of rats. [Methods] In situ recirculation perfusion technique was used to study the abso...
关键词:CURCUMIN MONOPHOSPHATE In SITU recirculation PERFUSION Small INTESTINE ABSORPTION High performance liquid chromatography 
Effect of Yiqihuoxue prescription on myocardial energy metabolism after myocardial infarction via cross talk of liver kinase B1-depen-dent Notch1 and adenosine 5'-monophosphate-activated protein kinase被引量:8
《Journal of Traditional Chinese Medicine》2017年第3期378-386,共9页Wu Jiangong Chen Xi Guo Shuwen Liu Wenchen Zhang Lu Li Fanghe Wu Jiani Huang Xiaolou Cai Qian Tan Xiaobo Wang Hui 
Supported by the National Natural Science Foundation of China:Study of Influence of Supplementing Qi and Activating Blood Circulation Herbs on Microvascular Dysfunction and Related Regulators of Myocardial Infarction Rats(No.81173142);Study of Influence of Supplementing Qi and Activating Blood Circulation Herbs on Mitochondrial Energy Metabolism and Signal Transduction of Myocardial Ischemia Rats(No.81473552);The Basic Research Program(graduate program)of Beijing university of Chinese Medicine:Study of Influence of Supplementing Qi and Activating Blood Circulation Herbs on Notch Signal Network of Myocardial Infarction Rats(No.2016-JYB-XS034)
OBJECTIVE: To investigate the effect of Yiqihuoxue prescription(YQHX) from Traditional Chinese Medicine(TCM) on myocardial glucose and lipid metabolism after myocardial infarction via the cross talk between the liver ...
关键词:Myocardial infarction Reinforcing Qi ac-tivating blood Lipid metabolism Receptor  Notch1 AMP-activated protein kinases 
How does resveratrol influence the genesis of some neurodegenerative diseases?被引量:1
《Neural Regeneration Research》2016年第1期86-87,共2页Ester Tellone Antonio Galtieri Annamaria Russo Silvana Ficarra 
Advancing age and increased lifespan of human populations worldwide in the mid-nineteenth century,have led to a significant increase in the incidence of neurodegenerative diseases one of the major cause of disability ...
关键词:resveratrol disability populations genesis superoxide neuronal chromosome prevention incidence monophosphate 
Dan-gua Fang (丹瓜方) Improves Glycolipid Metabolic Disorders by Promoting Hepatic Adenosine 5'-monophosphate Activated Protein Kinase Expression in Diabetic Goto-kakizaki Rats被引量:12
《Chinese Journal of Integrative Medicine》2015年第3期188-195,共8页蓝元隆 黄苏萍 衡先培 陈玲 李鹏辉 吴静 杨柳清 潘旭东 林彤 程心玲 林青 陈斯歆 
Supported by the National Natural Science Foundation of China(No.81173179);the Natural Science Foundation of Fujian Province(No.2011J01198);the Fujian Medical Innovation Project(No.2009-CX-19);the Research Foundation of Fujian Health Department(No.Zlcnfm02);the Fujian Provincial Department of Education Category A Projects(No.JA09131);the Fujian Health Department of Traditional Chinese Medicine Research(No.WZY0920);the CHEN Ke-ji Integrative Medicine Development Fund(No.CKJ2008047,CKJ2009004);the Integrative Medicine of Fujian Key Laboratory of Age-related Diseases Funded Projects(No.2008J1004-10)
Objective:To investigate the effect of Dan-gua Fang(丹瓜方) on adenosine 5’-monophosphate(AMP) activated protein kinase(AMPK) α expression in liver and subsequent improvement of glucose and lipid metabolism.M...
关键词:Dan-gua Fang Goto-Kakizaki rat adenosine 5’-monophosphate activated protein kinase type 2 diabetes mellitus liver glucose and lipid metabolism 
姜黄素抑制尾加压素-Ⅱ诱导的人晶状体上皮细胞增殖及[Ca^(2+)]_i、cAMP、cGMP信号转导机制
《中国病理生理杂志》2010年第A10期2068-2069,共2页祁明信 黄秀榕 胡俊 杨丽英 
关键词:信号转导机制 Ca 细胞增殖 晶状体上皮 加压素 环化腺苷酸 MONOPHOSPHATE PROLIFERATING 增殖细胞核抗原 curcumin 
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