Background: Etomidate (R- 1 -[ 1 -ethylphenyl] imidazole-5-ethyl ester) is a widely used anesthetic drug that had been reported to contribute to cognitive deficits after general surgery. However, its underlying mec...
Acknowledgements This study was supported by research grants from the National Natural Science Foundation of China (30770898 and 30971260) and the Natural Science Foundation of Guangdong Province (8251008901000013).
Aim: To examine the inhibitory effects of adenosine monophosphate-activated protein kinase (AMPK) activation on cardiac hypertrophy in vitro and to investigate the underlying molecular mechanisms. Methods: Culture...
Project (No. 07C26213101283) supported by the Innovation Fundfor Technology Based Firms from the Ministry of Science andTechnology of China
Nucleoside phosphorylases (NPases) were found to be induced in Enterobacter aerogenes DGO-04, and cytidine and cytidine 5′-monophosphate (CMP) were the best inducers. Five mmol/L to fifteen mmol/L cytidine or CMP cou...
Placental CRH plays a major role in the mechanisms controlling human pregnancy and parturition. Understanding how placental CRH production is regulated is therefore of importance. Previously we have shown that placent...
Pulse radiolysis of chlorogenic acid (CGA) as well as CGA and 2′\|deoxyguanosine\|5′\|monophosphate (dGMP) has been carried out in aqueous solution using pulse radiolytic technique. From detailed kinetic analyses, t...
Project supported by the National Natural Science Foundation of China.
Diacylglycerol (DG) and cAMP, two intracellular second messengers, play importantroles in responding to the stimulation of extracellular signal. DG activates protein kinaseC (PKC), and cAMP activates protein kinase A ...