AGONISTS

作品数：136被引量：373H指数：10
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相关作者：王昊刘洪瑞李智郭政东蒋华良更多>>
相关机构：北京大学中国医科大学中国科学院北京中医药大学更多>>
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Strigolactone agonists/antagonists for agricultural applications:New opportunities被引量：1
《Advanced Agrochem》2022年第1期61-72,共12页Da-Wei Wang Zhen Xi 
funding support by the National Natural Science Foundation of China(No.22077072 and 21837001);the Frontiers Science Center for New Organic Matter of Nankai University(No.63181206);the Haihe Laboratory of Sustainable Chemical Transformations(No.YYJC202102).
Strigolactones(SLs)are a new class of phytohormones that not only act as signalling molecules with external rhizospheric fungus and stimulate the seed germination of root parasite weeds,but also regulate many aspects ...
关键词：STRIGOLACTONE Strigolactone agonist Strigolactone antagonist Seed germination Plant hormone 
Hormone naive prostate cancer： predicting and maximizing response intervals被引量：4
《Asian Journal of Andrology》2015年第6期929-935,I0007,I0008,共9页Judd W Moul 
Hormone naive advanced prostate cancer is subdivided into two disease states： biochemical recurrence and traditional M 1 （metastatic） prostate cancer and characterized by no prior hormonal therapy or androgen depri...
关键词：androgen deprivation therapy cancer gonadotrophin-releasing hormone antagonists hormonal therapy luteinizing hormone-releasing hormone agonists prostate prostate-specific antigen TESTOSTERONE 
The seeming paradox of adenosine receptors as targets for the treatment of Alzheimer's disease: agonists or antagonists?被引量：1
《Neural Regeneration Research》2015年第2期205-207,共3页Rubina Marzagalli Alessandro Castorina 
Alzheimer＇s disease （AD） is the most common neurodegenerative disorder, and its incidence is relatively high among elderly people, affecting about 1-2% of the population between 60-65 years old and rising dramatica...
关键词：The seeming paradox of adenosine receptors as targets for the treatment of Alzheimer’s disease agonists or antagonists 
Support vector machine for SAR/QSAR of phenethyl-amines被引量：2
《Acta Pharmacologica Sinica》2007年第7期1075-1086,共12页Bing NIU Wen-cong LU Shan-sheng YANG Yu-dong CAI Guo-zheng LI 
Project supported by the National Natural Science Foundation of China(№ 20373040 and 20503015)
Aim： To discriminate 32 phenethyl-amines between antagonists and agonists, and predict the activities of these compounds. Methods： The support vector machine （SVM） is employed to investigate the structure-activity...
关键词：support vector machine QSAR phenethyl amines ANTAGONISTS AGONISTS 
Effects of intrathecal NMDA and AMPA receptors agonists or antagonists on antinociception of propofol被引量：17
《Acta Pharmacologica Sinica》2004年第1期9-14,共6页Ai-junXU Shi-mingDUAN Yin-mingZENG 
AIM: To study the effects of intrathecal (it) agonists and antagonists of N-methyl-D-aspartate (NMDA) and alpha amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors and NMDAR1 antisense oligodeoxynucle...
关键词：N-methyl-D-aspartate receptors AMPA receptors spinal injections ANTINOCICEPTION PROPOFOL 
Effects of various muscarinic ligands on M_2AChR-G_i1a fusion protein expressed in Sf9 insect cells被引量：1
《Acta Pharmacologica Sinica》2002年第3期230-235,共6页王昊 郭政东 李智 刘洪瑞 
Project supported by the National Natural Science Foundation of China (№ 30171077) and Natural Sciencc Foundation of Liaoning Province (№ 002039).
To generate M2AChR-Gila fusion protein in baculovirus-Sf9 cells system and detect the effects of various muscarinic ligands and magnesium ion on the interaction of fused M2AChR and Gila. METHODS:M2AChR-Gila fused DNA ...
关键词：muscannic receptors inhibitory G G-PROTEIN recombinant fusion proteins muscannic agonists muscannic antagonists adenosine triphosphate guanosine triphosphate guanosine diphosphate radio-ligand assay 
Effects of various muscarinic ligands on M<sub>2</sub>AChR-G<sub>i</sub>1a fusion protein expressed in Sf9 insect cells被引量：1
《Acta Pharmacologica Sinica》2002年第3期42-48,共页王昊 郭政东 李智 刘洪瑞 
Project supported by the National Natural Science Foundation of China (№ 30171077) and Natural Sciencc Foundation of Liaoning Province (№ 002039).
To generate M2AChR-Gila fusion protein in baculovirus-Sf9 cells system and detect the effects of various muscarinic ligands and magnesium ion on the interaction of fused M2AChR and Gila. METHODS:M2AChR-Gila fused DNA ...
关键词：muscannic receptors inhibitory G G-PROTEIN recombinant fusion proteins muscannic agonists muscannic antagonists adenosine triphosphate guanosine triphosphate guanosine diphosphate radio-ligand assay 
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