云南高校图书馆联盟文献共享服务平台- PATHOBIOLOGY

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A review on pathobiology of circulating tumour plasma cells:The sine qua non of poor prognosis in plasma cell neoplasms: 《Oncology Research》2025年第5期1055-1068,共14页PRATIBHA SUKU AISHWARYA DASH ARAVIND RADHAKRISHNAN PANKAJ MALHOTRA MAN UPDESH SINGH SACHDEVA; Circulating plasma cells(CPCs)in patients of plasma cell neoplasm have been an area of intense research in recent decades.Circulating tumor plasma cells(CTPCs)might represent a sub-clone of tumor cells that have exite...; 关键词：Circulating Plasma Cells(CPCs) Multiple Myeloma(MM) Flow cytometry Circulating Tumor Plasma Cells(CTPCs) Microenvironment Monoclonal gammopathy

Diabetic cardiomyopathy:Emerging therapeutic options: 《World Journal of Diabetes》2024年第8期1677-1682,共6页Cornelius James Fernandez Sahana Shetty Joseph M Pappachan; Diabetic cardiomyopathy(DbCM)is a common but underrecognized complication of patients with diabetes mellitus(DM).Although the pathobiology of other cardiac complications of diabetes such as ischemic heart disease and ...; 关键词：Diabetic cardiomyopathy Diabetic cardiomyopathy Heart failure PATHOBIOLOGY Teneligliptin

Long-term olfactory loss post-COVID-19:Pathobiology and potential therapeutic strategies: 《World Journal of Otorhinolaryngology-Head and Neck Surgery》2024年第2期148-155,共8页Sarah Kim John B.Finlay Tiffany Ko Bradley J.Goldstein; An acute loss of smell emerged as a striking symptom present in roughly half of the people infected with the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)virus in the early phases of the COVID-19 pandemi...; 关键词：HYPOSMIA INFLAMMATION long-COVID parosmia

Animal models of heart failure with preserved ejection fraction(HFpEF):from metabolic pathobiology to drug discovery: 《Acta Pharmacologica Sinica》2024年第1期23-35,共13页Si Gao Xue-ping Liu Ting-ting Li Li Chen Yi-ping Feng Yu-kun Wang Yan-jun Yin Peter J.Little Xiao-qian Wu Suo-wen Xu Xu-dong Jiang; supported by grants from the National Natural Science Foundation of China(No.82160278,81500214,82370444 and 82070464);the Guangxi Natural Science Foundation(No.2023GXNSFAA026209);the Doctoral Foundation of Guangxi University of Science and Technology(No.20Z23)。; Heart failure(HF)with preserved ejection fraction(HFpEF)is currently a preeminent challenge for cardiovascular medicine.It has a poor prognosis,increasing mortality,and is escalating in prevalence worldwide.Despite ac...; 关键词：animal models diabetes HFpEF hypertension metabolic inflexibility OBESITY

SYNGR4 and PLEKHB1 deregulation in motor neurons of amyotrophic lateral sclerosis models: potential contributions to pathobiology: 《Neural Regeneration Research》2022年第2期266-270,共5页Rita F.Marques Kent E.Duncan; supported in part by funding from the Else Kr?ner Fresenius Stiftung(Co-PI);the Werner Otto Stiftung(PI)(to KED)。; Amyotrophic lateral sclerosis is the most common adult-onset neurodegenerative disease affecting motor neurons. Its defining feature is progressive loss of motor neuron function in the cortex, brainstem, and spinal co...; 关键词：amyotrophic lateral sclerosis glucagon-like peptide-1 receptor motor neuron disease mouse model NEURODEGENERATION PHOSPHATIDYLSERINE pleckstrin homology domain synaptogyrin TAR DNA-binding protein-43 vesicle transport

Sex disparity in hepatocellular carcinoma owing to NAFLD and non-NAFLD etiology:epidemiological findings and pathobiological mechanisms被引量：1: 《Hepatoma Research》2020年第12期12-23,共12页Amedeo Lonardo Stefano Ballestri Pierce KHChow Ayako Suzuki; Nonalcoholic fatty liver disease(NAFLD)exhibits sexual dimorphism,with men being more exposed than women to the risk of simple steatosis,nonalcoholic steatohepatitis fibrosis,and hepatocellular carcinoma(HCC),while th...; 关键词：Liver cancer PATHOBIOLOGY personalized medicine sex differences

Molecular pathobiology of scleritis and its therapeutic implications被引量：1: 《International Journal of Ophthalmology(English edition)》2020年第1期163-175,共13页Undurti N Das; Scleritis and other autoimmune diseases are characterized by an imbalance in the levels of pro-inflammatory and anti-inflammatory molecules with the balance tilted more towards the former due to the failure of recogni...; 关键词：SCLERITIS autoimmune diseases bioactive lipids INFLAMMATION MICRONUCLEUS CYTOKINES resolution of inflammation

Clinicohistopathological implications of phosphoserine 9 glycogen synthase kinase-3β/β-catenin in urinary bladder cancer patients被引量：2: 《World Journal of Clinical Oncology》2019年第4期166-182,共17页Niharika Maurya Rinni Singh Apul Goel Atin Singhai Uday Pratap Singh Vinita Agrawal Minal Garg; BACKGROUND Aberrant activation of phosphorylated form of glycogen synthase kinase-3β[pS9 GSK-3β(Serine 9 phosphorylation)] is known to trigger Wnt/β-catenin signal cascade but its clinicohistopathological implicati...; 关键词：PATHOBIOLOGY Target genes Tumor stage and grade Wnt/β–catenin signal cascade UROTHELIAL carcinoma of BLADDER

Advances in Pathobiology of Primary Central Nervous System Lymphoma被引量：6: 《Chinese Medical Journal》2017年第16期1973-1979,共7页Xue-Liang Yang Yuan-Bo Liu; This work was supported by the grant of the Beijing Natural Science Foundation of China （No. 7172071） and National Natural Science Foundation of China （No. 81272842）.; Objective： Primary central nervous system lymphoma （PCNSL） is a specific type ofnon-Hodgkin lymphoma with poor prognosis. The rare incidence of this disease and difficulty to obtain sufficient tissue material imped...; 关键词：BIOLOGY Biomarkers HISTOPATHOLOGY PATHOGENESIS Primary Central Nervous System Lymphoma

Synthetic cell pathobiology to study neurodegeneration： defining new therapeutic targets in astroglia被引量：1: 《Neural Regeneration Research》2016年第2期234-235,共2页Matjaz Stenovec: Robert Zorec; supported by the Slovenian Research Agency grants P3310,J3 3632,J3 4051,J3-4146,J3 6790,J3 7605; Synthetic biology is the design and construction of new biological parts,devices,and systems,and the re-design of existing,natural biological systems for useful purposes.This new interdisciplinary effort has gained in...

PATHOBIOLOGY