VANCOMYCIN

作品数：98被引量：152H指数：6
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Correlations of vancomycin trough concentration and its efficacy and toxicity in patients in the intensive care unit
《World Journal of Clinical Cases》2025年第16期18-28,共11页Teng Guo Li-Ying Du Ming-Feng Liu Xia-Jin Zhou Xin-Ran Chen 
Supported by the Key Project Plan of Health and Medical Science Research in Hebei Provincial Health Commission,No.20190745.
BACKGROUND Plasma concentration monitoring is crucial for optimizing vancomycin use,particularly in patients in the intensive care unit(ICU).However,the reference interval for vancomycin plasma concentration remains u...
关键词：VANCOMYCIN Therapeutic drug monitoring Intensive care unit Trough concentration Methicillin-resistant Staphylococcus aureus infection Area under the curve 
Vancomycin-encapsulated hydrogel loaded microarc-oxidized 3D-printed porous Ti6Al4V implant for infected bone defects:Reconstruction,anti-infection,and osseointegration
《Bioactive Materials》2024年第12期18-31,共14页Teng Zhang Wenhao Zhou Wanliang Yang Jingwei Bi Hao Li Xianlei Gao Baoliang Zhang Guidong Shi Ka Li Zhijian Wei Xin Pan Shiqing Feng 
supported by the National Natural Science Foundation of China[grant number 82202729];the Natural Science Foundation of Shandong Province[grant number ZR2022QH261];the Taishan Scholar Project of Shandong Province[grant number tsqn202306355];the National Natural Science Foundation of China[grant number 32101087];the Tianjin Municipal Science and Technology Program(21JCZDJC01100).
Infected bone defect is a formidable clinical challenge.Conventional approaches to prevention and treatment for infected bone defects are unsatisfactory.The key elements of the treatment are bone defect reconstruction...
关键词：Porous Ti6Al4V implants Infected bone defects ANTI-INFECTION OSSEOINTEGRATION 
Therapeutics involved in managing initial and recurrent Clostridium difficile infection:An updated literature review
《World Journal of Gastrointestinal Pharmacology and Therapeutics》2024年第5期1-14,共14页Vignesh K Nagesh Hadrian Hoang-Vu Tran Daniel Elias Izage Kianifar Aguilar Tanni Sethi AiswaryaMenon Charlene Mansour Florchi Furman Kylie Tsotsos Talia Subar Auda Auda Aman Sidiqui JevonLamar Nikita Wadhwani Shraboni Dey Abraham Lo Adam Atoot Simcha Weissman Humberto Sifuentes Ayrton I Bangolo 
Clostridium difficile infection(CDI)has been increasing due to the effect of recurrent hospitalizations.The use of antibiotics has been shown to alter the gut microbiome and lead to CDIs.The treatment is limited to th...
关键词：Clostridium difficile ANTIBIOTICS VANCOMYCIN Fidaxomicin Prevention Bezlotoxumab Fecal microbiota transplant 
Invitro pharmacodynamicstudyof ceftobiprole,vancomycin,linezolid and daptomycin against staphylococcal bloodstream infections
《China Medical Abstracts(Internal Medicine)》2024年第2期83-84,共2页李玲琴 
Objective To evaluate the antibacterial efficacy of ceftobiprole,vancomycin,linezolid,and daptomycin against Staphylococcus aureus(SAU)and coagulasenegative Staphylococcus(CNS)bloodstream infections,which can provide ...
关键词：dosage Blood INFECTIONS 
Does topical vancomycin prevent fracture-related infections in closed fractures undergoing open reduction and internal fixation?A randomised controlled trial
《Chinese Journal of Traumatology》2024年第2期71-76,共6页Mohit Gandhi Gopisankar Balaji Jagdish Menon Ruben Raj Thomas 
Purpose:The role of topical vancomycin in fracture-related infection(FRI)is debatable.Very few studies have reported their efficacy in open and high-risk extremity fractures.This study aimed to assess topical vancomyc...
关键词：INFECTIONS ANTIBIOTICS VANCOMYCIN FRACTURES 
Vancomycin flushing syndrome in orthopaedic practice:A case report被引量：2
《World Journal of Orthopedics》2023年第10期771-775,共5页Fawaz M Al-Anii Mir Sadat-Ali Khalid Waleed Al-Tabash Ahmad I AlMulhim Sulaiman A AlMousa Abdulaziz M AlHawas 
BACKGROUND Vancomycin flushing syndrome(VFS),also known as red man syndrome,is an allergic reaction to vancomycin.It typically presents as a rash on the face,neck,and upper torso after intravenous administration of va...
关键词：VANCOMYCIN Anaphylactic reactions Red man syndrome Vancomycin flushing syndrome Case report 
Evaluating Vancomycin Clinical Outcomes Using Area under the Curve versus Trough Based Dosing Strategies
《Advances in Infectious Diseases》2023年第3期442-451,共10页Chelsea A. Schneider William Rodriguez Jenny Martinez William R. Wolowich 
Background: The 2020 consensus guidelines recommend AUC guided dosing as the preferred monitoring method for vancomycin. AUC based dosing has shown to reduce incidence of acute kidney injury (AKI), utilize lower daily...
关键词：AUC MRSA PHARMACOKINETICS Trough Based Dosing VANCOMYCIN 
Fabrication, bacteriostasis and osteointegration properties researches of the additively-manufactured porous tantalum scaffolds loading vancomycin被引量：2
《Bioactive Materials》2023年第6期450-462,共13页Hu Qian Ting Lei Long Hua Yu Zhang Dongyu Wang Jiangyu Nan Wenbin Liu Yan Sun Yihe Hu Pengfei Lei 
supported by the Key research and development program of Hunan Province(Grant No.2020SK2008 and 2021GK2012);the Major science and technology projects of Changsha City(Grant No.kh2003016);Clinical research fund of National Clinical Research Center for Geriatric Disorders(Xiangya Hospital,Grant No.2020LNJJ15);The Natural Science Foundation Exploration Project of Zhejiang Province,China(Grant No.Y23H060040);the Natural Science Foundation of Hunan Province,China(Grant No.2022JJ30934).
Infected bone defects(IBDs)remains a challenging problem for orthopedists.Clinically,routine management for IBDs has two stages:debridement and systematic antibiotics administration to control infection,and secondary ...
关键词：Infected bone defects Porous tantalum PLGA microspheres VANCOMYCIN 
Clinical Evaluation of a Vancomycin Dosage Strategy Based on a Serum Trough Concentration Model in Elderly Patients with Severe Pneumonia被引量：2
《Biomedical and Environmental Sciences》2023年第5期397-405,共9页YAN Wei SUN Xiao Yan WANG Meng ZHAO Fei Fan ZHOU Qing Tao 
funded as a key clinical project of Peking University Third Hospital [No. BYSY2018021];funded by Beijing Natural Science Foundation [7212128]。
Objective This study aimed to evaluate the clinical benefits of a vancomycin dosage strategy based on a serum trough concentration model in elderly patients.Methods This prospective single-center, open-label, randomiz...
关键词：PNEUMONIA Clinical trials VANCOMYCIN Trough concentration Elderly patients 
Actions of N-acetylcysteine,daptomycin,vancomycin,and linezolid on methicillin-resistant Staphylococcus aureus biofilms in the ventriculoperitoneal shunt infections:an experimental study被引量：1
《Chinese Neurosurgical Journal》2022年第4期239-247,共9页Tuba Kuruoglu Gamze Altun Enis Kuruoglu Derya BayırlıTuran Mehmet EminÖnger 
Background:Shunt systems are used to provide cerebrospinal fluid drainage in the treatment of hydrocephalus.Recently,antibiotic-impregnated shunt systems are used to prevent colonization in the ventriculoperitoneal ca...
关键词：METHICILLIN-RESISTANT Biofilm Antibiotic-impregnated catheters Scanning electron microscope 
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