GEMIFLOXACIN

作品数:11被引量:21H指数:3
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相关领域:医药卫生更多>>
相关作者:陈胜昔郭惠元郑莉徐楠更多>>
相关机构:中国医学科学院北京协和医学院四川大学华西医院更多>>
相关期刊:《德国临床用药》《Journal of Pharmaceutical Analysis》《American Journal of Analytical Chemistry》《药学进展》更多>>
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Partitioning Behavior of Gemifloxacin in Anionic, Cationic and Nonanionic Surfactants. Calculation of Dermal Permeability Coefficient
《Pharmacology & Pharmacy》2015年第4期207-211,共5页Theophilus C. Onyekaba Chukwudinma C. Achilefu Chika J. Mbah 
Transdermal delivery acts as an alternative to oral delivery of drugs and possibly provids also an alternative to hypodermic injection. Transdermal delivery when compared to oral route has a variety of advantages name...
关键词:GEMIFLOXACIN SURFACTANTS PARTITION Coefficient 
Development and Validation of Stability Indicating HPTLC Assay for Determination of Gemifloxacin Mesylate in Dosage Forms
《American Journal of Analytical Chemistry》2015年第2期85-97,共13页Ashraf M. Mahmoud Noha N. Atia Salwa R. El-Shabouri Wesam M. El-Koussi 
Simple and sensitive stability-indicating high performance thin layer chromatography (HPTLC) assay was developed and validated for quantitative determination of the antibacterial drug, gemifloxacin mesylate (GFX) in p...
关键词:HPTLC GEMIFLOXACIN MESYLATE Stability Indicating ASSAY KINETICS Degradation PHARMACEUTICAL Preparations 
Anodic voltammetric determination of gemifloxacin using screen-printed carbon electrode被引量:1
《Journal of Pharmaceutical Analysis》2013年第2期132-136,共5页Abd-Elgawad Radi Amira Khafagy Amira El-shobaky Hatem El-mezayen 
The electrochemical oxidation behavior and voltammetric assay of gemifloxacin were investigated using differential-pulse and cyclic voltammetry on a screen-printed carbon electrode.The effects of pH,scan rates,and con...
关键词:Screen-printed carbon electrode Voltammetry Gemifloxacin Pharmaceutical analysis 
Gemifloxacin引起的皮疹─案例报告
《臺灣臨床藥學雜誌》李梅君(Mei-Chun Lee) 李聰明(Chung-Ming Lee) 王森洤(Sheng-Chuan Wang) 李韋瑩(Wei-Ying Lee) 
Gemifloxacin是新一代的口服呼吸道氟化恩菎类(fluoroquinolone, FQ),藉由其独特的结构变化,除了降低抗药性的发生且对肺炎链球菌(Streptococcus pneumoriae)及非典型细菌也有良好的抗菌效果。FDA於2003年4月核准治疗轻到中度的...
关键词:氟化恩菎類 斑丘疹 
Gemifloxacin for the treatment of community-acquired pneumonia and acute exacerbation of chronic bronchitis: a meta-analysis of randomized controlled trials被引量:3
《Chinese Medical Journal》2012年第4期687-695,共9页Zhang Lei Wang Rui Matthew, Falagas E. Chen Liang-an Liu You-ning 
Background Gemifloxacin is a fluoroquinolone antibiotic with broad spectrum of antibacterial activity.The aim of the study was to evaluate the comparative effectiveness and safety of gemifloxacin for the treatment of ...
关键词:GEMIFLOXACIN QUINOLONES BETA-LACTAMS SAFETY 
Spectrophotometric methods for the determination of gemifloxacin in pharmaceutical formulations
《Acta Pharmaceutica Sinica B》2011年第4期248-253,共6页Sara A.M.Ebraheem Abdalla A.Elbashir Hassan Y.Aboul-Enein 
This paper describes two simple spectrophotometric methods for the determination of the antibiotic gemifloxacin mesylate(GFX)in pharmaceutical formulations.The first(A)is an indirect method in which oxidation of the d...
关键词:Gemifloxacin mesylate SPECTROPHOTOMETRY 1 2-Naphthoquinone-4-sulphonate Pharmaceutical formulations 
The synthesis and activity in vitro of a series of 8-difluoromethoxy quinolones: Analogues of gemifloxacin被引量:1
《Chinese Chemical Letters》2007年第10期1169-1172,共4页Jin Jiang Jiu Yu Liu Hui Yuan Guo 
7-[4-(Aminomethyl)-3-(methoxyimino)pyrrolidin- 1-yl]- 1-cyclopropyl-6-fluoro-8-difluoromethoxy- 1,4-dihydro-4-oxoquino- line-3-carboxylic acid and its analogues have been prepared and evaluated for antibacterial a...
关键词:QUINOLONE SYNTHESIS Antibacterial activity 
喹诺酮类抗菌药 吉米沙星gemifloxacin被引量:5
《世界临床药物》2005年第1期58-58,共1页须媚 
1商品名 Factive 2开发与上市厂商 由韩国LG Life Sciences公司研制,2003年4月获美国FDA许可,2003年7月首次在韩国上市。
关键词:吉米沙星 喹诺酮类抗菌药 首次 美国FDA 上市 商品名 许可 厂商 公司 韩国 
新的广谱、高效喹诺酮类抗菌药gemifloxacin被引量:11
《国外医药(抗生素分册)》2002年第6期279-283,共5页陈胜昔 郭惠元 
gemifloxacin是由韩国LG公司研制 ,美国史克公司开发的新的广谱高效喹诺酮类抗菌药 ,它对肺炎链球菌的MIC90 为 0 0 3mg/L ,其活性是曲伐沙星和莫西沙星的 4~ 8倍 ,是环丙沙星的 3 0~ 60倍 ;对葡萄球菌 (金黄色葡萄球菌除外 )的MIC90...
关键词:GEMIFLOXACIN 喹诺酮类药 药效学 药物动力学 临床研究 
gemifloxacin的药理和临床研究进展
《国外医药(抗生素分册)》2002年第3期131-136,144,共7页郑莉 徐楠 
gemifloxacin是新的第四代喹诺酮类抗菌药 ,其抗菌谱广 ,对革兰氏阳性菌有很强的杀菌活性 ,同时也保持了对革兰氏阴性菌的抗菌活性 ,而且对厌氧菌、枝原体、衣原体也有一定的抗菌作用。gemifloxacin由于 C7-位被氨基吡咯环取代 ,与细菌 ...
关键词:GEMIFLOXACIN 临床研究 安全性 药物动力学 喹诺酮类抗菌药 
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