supported by the National Natural Science Foundation of China(Nos.21901185 and 22301216);funds provided by Tianjin Normal University。
Herein,we report the migratory hydroarylation of unactivated alkenes with aryl iodides using native and weakly coordinating amide directors under mild conditions.Synergistic coordination of the monodentate directing g...
the National Key R&D Program of China(No.2021YFF0701600);NSFC(No.22031004);the Shanghai Municipal Education Commission(No.20212308);China Postdoctoral Science Foundation(No.2022M713667);STCSM(No.23ZR1445600).
Heterogeneous asymmetric catalysis is an important strategy for the industrial production of chiral compounds.Herein,we reported a polymer-bound Xu-Phos-derived palladium catalyst that shows good performance in hetero...
the National Key R&D Program of China(2021YFA1501700);the National Natural Science Foundation of China(21825109,21821002,22072178,22293013).
Comprehensive Summary The direct use of non-prefunctionalized arene and alkane as the starting materials to construct Caryl−Calkyl bond is an unfulfilled target and approaches to this challenge rarely surface in metho...
financial support from the National Natural Science Foundation of China (No. 21472033);the National Key R&D Program of China (No. 2018YFB1501604);the Fundamental Research Funds for the Central Universities (No. PA2020GDKC0021)。
The hydroarylation reaction of terminal alkynes with arylboronic acids catalyzed by low(400 ppm) loadings of palladium has been developed. The reaction is broad in scope and high-yielding, even on multigram scale. It ...
the National Natural Science Foundation of China(nos.21790330 and 91956000)and the“111”Project(no.B06005)of the Ministry of Education of China for financial support.
The regio-and enantioselective functionalization of 1,3-dienes has become a powerful tool for the synthesis of allylic compounds,yet it remains a challenge for aliphatic dienes.Herein,we report a nickel-catalyzed asym...
We gratefully acknowledge the National Natural Science Foundation of China(22122103,22101130,22001116,21971108,21971111,21732003);the National Key Research and Development Program of China(2021YFC2101901);the Fundamental Research Funds for the Central Universities(020514380252);the Natural Science Foundation of Jiangsu Province(Grant No.BK20190006);the Guangdong Basic and Applied Basic Research Foundation(2020A1515110816);the"Innovation&Entrepreneurship Talents Plan"of Jiangsu Province.Nian Li,Chuan-Gang Zhao,Junheng Liu are warmly acknowledged to reproduce experimental procedures for products 3ii,5p and 3a.
The arylethylamine framework is a prevalent motif in a great range of biologically important organic compounds.One intractable task for frontline drug discovery is to find structurally new medicine candidates instead ...
We thank the National Natural Science Foundation of China(no.81803406 and U1804283);the Foundation of Henan Educational Committee(19A150009)for financial support.
An efficient metal-free intramolecular hydroarylation reaction of alkynes is described here.A series of aryl and N-group attached alkynes generated the intramolecular hydroarylation products in high yields.
the National Natural Science Foundation of China(grant nos.21732006,51821006,21927814,and 51961135104);the Strategic Priority Research Program of CAS(grant nos.XDB20000000 and XDB37040000);the USTC Research Funds of the Double First-Class Initiative(grant no.YD3530002002);the Users with Excellence Program of Hefei Science Center CAS(grant nos.2019HSCUE017 and 2019HSC-UE005).
Chiral dialkyl carbinols and their derivatives are significant synthetic building blocks in organic chemistry and related fields.The development of convenient and efficient methods to access these compounds has long b...
the financial supports from the National Natural Science Foundation of China(Nos.22022111,21871257,21801240);the Natural Science Foundation of Fujian Province(No.2020J02008);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB20000000)。
A visible-light-induced spirocyclizative hydroarylation via reductive dearomatization of a series of non activated arenes including 2-phenyl indoles and naphthalene derivatives under mild conditions is de scribed.An i...
the Shenzhen Overseas High-level Talents Innovation Plan of Technical Innovation Project(No.KQJSCX20180319114439973)for financial support.
A highly efficient kinetic resolution of racemic 2-substituted 1,2-dihydroquinolines via Rh-catalyzed asymmetric hydroarylation has been described for the first time.A variety of arylboronic acids coupled with 2-subst...