GALANTHAMINE

作品数：6被引量：11H指数：2
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相关领域：理学医药卫生更多>>
相关作者：张宁郑由浒唐瑞仁董斌张乐芬更多>>
相关机构：兰州大学中南大学沈阳药科大学陕西师范大学更多>>
相关期刊：《Journal of Biomedical Science and Engineering》《Journal of Chinese Pharmaceutical Sciences》《Chinese Herbal Medicines》《精细化工中间体》更多>>
相关基金：国家自然科学基金福建省自然科学基金更多>>
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The mechanism of galanthamine regulating IL-1β/IL-1RA ratio to ameliorate inflammatory microenvironment被引量：1
《Journal of Chinese Pharmaceutical Sciences》2022年第10期773-781,共9页Jingting Kang Chao Ji 
National Natural Science Foundation of China (Grant No. 81100801);Peking Union Medical College Small-Scale Characteristic School Education Project。
In the present study,we aimed to evaluate the anti-inflammatory mechanism of galanthamine,a classic therapeutic drug for Alzheimer s disease(AD).The co-culture system of hippocampal nerve cell line HT-22 and microglia...
关键词：GALANTHAMINE INTERLEUKIN-1Β IL-1 receptor antagonist LIPOPOLYSACCHARIDE Inflammatory response 
Enzyme-assisted Extraction and Enrichment of Galanthamine from Lycoris aurea被引量：5
《Chinese Herbal Medicines》2016年第2期182-188,共7页Chun-lian Tian Peng Wang Ji-xin Qin Xiao-pan Liu Ke Song Zhuo-bing Xiao 
Hunan Provincial Science and Technology Department(2012TP4002-3);Zhangjiajie Science and Technology Bureau(2014YB17)
Objective To explore the optimum condition for complex enzyme-assisted extraction of galanthamine from Lycoris aurea by L_9（3~4） orthogonal array design and separation effect of cation exchange resin on galanthamine...
关键词：cation exchange resin enzyme-assisted extraction GALANTHAMINE Lycoris aurea SEPARATION 
An LC-MS/MS Method for the Simultaneous Determination of Lycorine and Galanthamine in Rat Plasma and Its Application to Pharmacokinetic Study of Lycoris Radiata Extract in Rats
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2014年第6期861-868,共8页周欣 刘月彬 黄珊 刘莹 
supported by the Natural Science Foundation of Fujian Province of China(No.2013J01382)
A rapid, sensitive, and selective liquid chromatography-tandem mass spectrometry was developed for the simultaneous determination of lycorine and galanthamine, two major constituents in Lycoris radiata extract, in rat...
关键词：liquid chromatography-tandem mass spectrometry Lycoris radiata extract PHARMACOKINETIC ratplasma 
Effect of cholinesterase inhibitor galanthamine on circulating tumor necrosis factor alpha in rats with lipopolysaccharideinduced peritonitis被引量：4
《Chinese Medical Journal》2010年第13期1727-1730,共4页LIU Zhi-hai MA Yue-feng WU Jun-song GAN Jian-xin XU Shao-wen JIANG Guan-yu 
This study was supported by grants from the National Natural Science Foundation of China （No. 30500531）, and the Key Science and Technology Program of Zhejiang Province （No. 2007C33084）.
Background The nervous system, through the vagus nerve and its neurotransmitter acetylcholine, can down-regulate the systemic inflammation in vivo, and recently, a role of brain cholinergic mechanisms in activating th...
关键词：cholinesterase inhibitors GALANTHAMINE tumor necrosis factor alpha vagus nerve 
Estimation of the galanthamine using derivative spectrophotometry in bulk drug and formulation被引量：1
《Journal of Biomedical Science and Engineering》2010年第4期439-441,共3页Karan Mittal Ramni Kaushal Rajashree Mashru Arti Thakkar 
Two simple, rapid, accurate, precise, reliable and economical spectrophotometric methods have been proposed for the determination of galanthamine hydrobromide (GH) in bulk and pharmaceutical formulation. First method ...
关键词：alanthamine Hydrobromide (GH) ZERO Order UV-SPECTROPHOTOMETRY First Derivative ZERO CROSSING SPECTROPHOTOMETRY 
加兰它敏(Galanthamine)的合成方法
《精细化工中间体》2007年第2期13-16,24,共5页杨青 郑由浒 唐瑞仁 
生物碱加兰它敏为可逆性乙酰胆碱酯酶(AChE)的抑制剂,对阿尔海默氏老年痴呆症有较好的疗效,介绍了以K3[Fe(CN)6]、钯络化物、三价碘化物等为氧化剂的氧化关环方法合成加兰它敏的方法,并总结了各种其外消旋体的拆分方法,简要评价了各种...
关键词：加兰它敏 阿尔海默氏 乙酰胆碱酯酶抑制剂 
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