GUIDED

作品数：855被引量：2145H指数：18
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A machine learning-guided design and manufacturing of wearable nanofibrous acoustic energy harvesters
《Nano Research》2024年第10期9181-9192,共12页Negar Hosseinzadeh Kouchehbaghi Maryam Yousefzadeh Aliakbar Gharehaghaji Safoora Khosravi Danial Khorsandi Reihaneh Haghniaz Ke Cao Mehmet R.Dokmeci Mohammad Rostami Ali Khademhosseini Yangzhi Zhu 
supported by Amirkabir University of Technology and the Terasaki Institute for Biomedical Innovation;supported by the U.S.DOE,Office of Science,Basic Energy Sciences,Materials Sciences and Engineering Division.
Nanofibrous acoustic energy harvesters(NAEHs)have emerged as promising wearable platforms for efficient noise-to-electricity conversion in distributed power energy systems and wearable sound amplifiers for assistive l...
关键词：wearable electronics acoustic energy harvester machine learning piezoelectric nanogenerator electrospun nanofiber 
Platelet-based bioactive systems guided precision targeting and immune regulation for cancer therapy
《Nano Research》2024年第9期8269-8284,共16页Xinyi Cai Long Qiu Zhenying Diao Lintao Cai Ting Yin Hong Pan 
supported by the National Key Research and Development Program of China(Nos.2022YFC2402400 and 2023YFA0915400);Guangdong Provincial Key Area R&D Program(No.2020B1111540001);the Natural Science Foundation of Guangdong Province(Nos.2024A1515010825,2024A1515030063,2022A1515010780,and 2022A1515011337);Guangdong Province Universities and Colleges Characteristic Innovation(No.2021KTSCX036);Traditional Chinese Medicine Research Project of Guangdong Province Traditional Chinese Medicine Bureau(No.20221206);Shenzhen Medical Research Fund(No.A2303057),Discipline Construction Project of Guangdong Medical University(No.4SG24015G);Construction Project of Nano Technology and Application Engineering Research Center of Guangdong Medical University(No.4SG24179G);Funds for PHD researchers of Guangdong Medical University in 2024.
The antitumor effects of conventional drug carriers are often attenuated and limited in application by biological barriers associated with tumor heterogeneity and resistance brought about by low tumor immunogenicity.W...
关键词：PLATELETS bionic targeting immune modulation precision therapy deep penetration 
Rational design of biodegradable semiconducting polymer nanoparticles for NIR-II fluorescence imaging-guided photodynamic therapy
《Nano Research》2024年第6期5399-5408,共10页Xuxuan Gu Jinlong Shen Zhiwei Xu Wenqi Wang Ying Wu Wen Zhou Chen Xie Quli Fan 
the National Natural Science Foundation of China(Nos.22174070 and 22205115);Natural Science Foundation of Jiangsu Province(No.BK20230060);Natural Science Foundation of Jiangsu University(No.21KJB150022);the Research startup fund of NJUPT(No.NY220149);Natural Science Foundation of NJUPT(No.NY221088);the Project of State Key Laboratory of Organic Electronics and Information Displays,Nanjing University of Posts and Telecommunications(Nos.GZR2022010012 and GZR2023010022);the Synergetic Innovation Center for Organic Electronics and Information Displays for the financial support.
Semiconducting polymer nanoparticles(SPNs)have shown great promise in second near-infrared window(NIR-II)phototheranostics.However,the issue of long metabolic time significantly restricts the clinical application of S...
关键词：near-infrared(NIR)-II fluorescence imaging semiconducting polymer nanoparticles photodynamic therapy tumor imaging 
Spectral computed tomography-guided photothermal therapy of osteosarcoma by bismuth sulfide nanorods
《Nano Research》2023年第7期9885-9893,共9页Yuhan Li Xiaoxue Tan Han Wang Xiuru Ji Zi Fu Kai Zhang Weijie Su Jian Zhang Dalong Ni 
This work was supported by the National Natural Science Foundation of China(No.82102190);the Foundation of National Facility for Translational Medicine(Shanghai)(No.TMSK-2021-122);Shanghai Municipal Health Commission Research Project(No.201840082);The animal study protocol was approved by the Institutional Animal Care and Use Committee at Shanghai JiaoTong University。
Osteosarcoma(OS)is the most normally primary malignant bone cancer in adolescents.Due to their analogous X-ray attenuation properties,healthy bones and malignancies with iodine enhancement cannot be distinguished by c...
关键词：dual-energy computed tomography NANOMEDICINE bismuth sulfide photothermal therapy OSTEOSARCOMA 
P-band center theory guided activation of MoS_(2) basal S sites for pHuniversal hydrogen evolution被引量：1
《Nano Research》2023年第5期6228-6236,共9页Chao Meng Yuanfeng Gao Yue Zhou Kang Sun Yanmin Wang Ye Han Qianqian Zhao Xuemin Chen Han Hu Mingbo Wu 
the National Natural Science Foundation of China(Nos.51901115 and 51802075);the Shandong Provincial Natural Science Foundation,China(Nos.ZR2019PEM001,ZR2019BB009,and ZR2020ZD08);the Young Talents Program in University of Hebei Province,China(No.BJ2019002).
The edge S sites of thermodynamically stable 2H MoS_(2)are active for hydrogen evolution reaction(HER)but the active sites are scarce.Despite the dominance of the basal S sites,they are generally inert to HER because ...
关键词：molybdenum disulfide p-orbital electron structure basal S sites hydrogen evolution synergistic mechanism 
Dual-modality magnetic resonance/optical imaging-guided sonodynamic therapy of pancreatic cancer with metal-organic nanosonosensitizer被引量：1
《Nano Research》2022年第7期6340-6347,共8页Yingli Chen Bo Yin Zhuang Liu Han Wang Zi Fu Xiuru Ji Wei Tang Dalong Ni Weijun Peng 
We greatly acknowledge the financial support from the National Natural Science Foundation of China(No.82102190);Shanghai Municipal Education Commission--Gaofeng Clinical Medicine Grant Support(No.20191805);the Foundation of National Facility for Translational Medicine(Shanghai)(No.TMSK-2021-122);this work was also supported,in part,by China Postdoctoral Science Foundation(No.2020M681326);Shanghai Sailing Program(No.19YF1410100);Shanghai Municipal Science and Technology Major Project(No.2018SHZDZX01);ZJ Lab,Shanghai Center for Brain-Inspired Technology.
Sonodynamic therapy(SDT)has been more attractive to carry out oncology treatments in recent years.However,imagingguided sonodynamic therapeutic nanomedicine is still a shortage in SDT development.In this work,we desig...
关键词：pancreatic tumor sonodynamic therapy THERANOSTICS magnetic resonance imaging 
Nanomaterials for neurodegenerative diseases:Molecular mechanisms guided design and applications
《Nano Research》2022年第4期3299-3322,共24页Tianzhong Li Xueyan Hou Yu Qi Xiaohan Duan Pengcheng Yan Haoru Zhu Zhongjian Xie Han Zhang 
This work was supported by the National Natural Science Fund of China(No.61961136001);the Guangdong Basic and Applied Research Foundation(No.2019B1515120043);Natural Science Foundation of Guangdong Province(No.2020A151501612);the Science and Technology Project of Shenzhen(No.JCYJ20180508152903208);The authors also acknowledged the support from the Photonics Center and Instrumental Analysis Center of Shenzhen University.
Successful treatment of neurodegenerative diseases(NDDs),including Alzheimer’s disease(AD),Parkinson’s disease(PD),and Huntington’s disease(HD),remains a significant challenge for neurologists due to the undesirabl...
关键词：neurodegenerative diseases molecular mechanisms NANOMATERIALS signaling pathways protein aggregation 
Exo/endogenous factors co-activatable nanodevice for spatiotem-porally controlled miRNA imaging and guided tumor ablation
《Nano Research》2022年第2期845-857,共13页Zhenqiang Wang Tao Ding Liucan Wang Shuai Wang Meizhen Zhou Jixi Zhang Kaiyong Cai 
supported in part by the National Natural Science Foundation of China(NSFC,Nos.51773022,51825302,21734002);Project No.2019CDQYSW041 supported by the Fundamental Research Funds for the Central Universities,Graduate Scientific Research and Innovation Foundation of Chongqing,China(No.CYB20068);the 100 Talents Program of Chongqing University(J.Z.)。
Remote activation of biomarker sensing holds a great promise of shifting the success of in vitro diagnostics to spatiotemporally controlled in vivo visualization of tumor,and in turn,imaging guided therapy.Herein,a"du...
关键词：thermo-activatable probe porous nanotransducer photothermal activation spatiotemporal miRNA imaging imaging-guided therapy 
Theory-guided construction of electron-deficient sites via removal of lattice oxygen for the boosted electrocatalytic synthesis of ammonia被引量：1
《Nano Research》2021年第5期1457-1464,共8页Li Zhang Shilong Jiao Xin Tan Yuliang Yuan Yu Xiang Yu-Jia Zeng Jingyi Qiu Ping Peng Sean C.Smith Hongwen Huang 
This work was supported by the National Natural Science Foundation of China (No. 21603208);Shenzhen Science and Technology Project (Nos. JCYJ20170412105400428 and JCYJ20180507182246321);Shenzhen Peacock Technological Innovation Project (No. KQJSCX20170727101208249);Fundamental Research Funds for the Central Universities, the Open Project Program of the State Key Laboratory of Silicon Materials, Zhejiang University, and China Postdoctoral Science Foundation (No. 2019M663058);This research was undertaken with the assistance of resources provided by the National Computational Infrastructure (NCI) facility at the Australian National University;allocated through both the National Computational Merit Allocation Scheme supported by the Australian Government and the Australian Research Council grant LE190100021 (Sustaining and strengthening merit-based access at NCI, 2019–2021).
Rational design of catalytic sites to activate the inert N≡N bond is of paramount importance to advance N2 electroreduction. Here, guided by the theoretical predictions, we construct a NiFe layered double hydroxide (...
关键词：nitrogen reduction density functional theory oxygen vacancies electron-deficient sites 
Mesoporous PtPd nanoparticles for ligand-mediated and imaging-guided chemo-photothermal therapy of breast cancer被引量：2
《Nano Research》2020年第6期1739-1748,共10页Yanpeng Jia Yang Song Ying Qu Jinrong Peng Kun Shi Dan Du He Li Yuehe Lin Zhiyong Qian 
This work was financially supported by the National Natural Science Foundation of China(Nos.31930067,31525009,31800797,and 31771096);the National Key Research and Development Program of China(Nos.2017YFC1103502 and 2016YFA0201402);the China Postdoctoral Science Foundation funded project(No.2018M631094);the Postdoctoral Innovation Talents Support Program(No.BX20180207);1·3·5 project for disciplines of excellence,West China Hospital,Sichuan University(No.ZYGD18002).
The synergistic therapy of chemotherapy and photothermal therapy(PTT)has been reported as a promising antitumor strategy.To achieve effective combination therapy,developing more suitable candidate nanomaterials with o...
关键词：inorganic nanoparticles photoacoustic imaging porous structure photothermal therapy CHEMOTHERAPY 
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