INFILTRATION

作品数:679被引量:1217H指数:14
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相关领域:医药卫生更多>>
相关作者:李丽储以微成来飞曾庆丰张立同更多>>
相关机构:西北工业大学中国农业大学复旦大学中山大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>
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Construction of a prognostic model based on the cuproptosis-related genes in pancreatic cancer
《Genes & Diseases》2025年第3期19-22,共4页Kaili Liao Yuxin Fu Shuman Guo Tingyi Qian Feifei Teng Yuhan Xu Bing Sun Hanqing Zhao Jingyan Zhang Ranhao Fan Jie Gao Xiaozhong Wang 
the Ethics Committee of the Second Affiliated Hospital of Nanchang University(approval numbers:(2023)CDYFYYLK(05e023)).
Pancreatic cancer(PC)is a commonly malignant tumor with a 5-year survival rate of only 10%.1 Cuproptosis is a newly discovered cell death mechanism closely associated with the development of tumors.This study mainly a...
关键词:immune infiltration marker genes comparing expression patterns construct prognostic model prognostic model cell death mechanism cuproptosis pancreatic cancer 
Utilization of cuproptosis-related lncRNAs to predict the prognosis of pancreatic cancer patients and explore their roles in immune cell infiltration and prognosis evaluation
《Genes & Diseases》2025年第3期39-41,共3页Kaili Liao Jinting Cheng Xiajing Yu Ziqian Liu Xue Zhang Yuxin Fu Wenyige Zhang Jie Liu Feifei Teng Yuxuan Xie Xiwen Yan Gaoquan Cao Bing Sun Hanqing Zhao Jingyan Zhang Xiaozhong Wang 
funded by the National Natural Science Foundation of China(No.82160405).
The prognosis of pancreatic cancer(PC)is difficult to predict1 and is extremely poor.2 Studies showed that cuproptosis was related to PC.The roles are not completely understood.It is considered that lncRNAs are closel...
关键词:pearson correlation analysis immune cell infiltration univariate cox regression analysis lncRNAs cuproptosis pancreatic cancer pancreatic cancer pc PROGNOSIS 
F-box protein 22: A prognostic biomarker for colon cancer associated with immune infiltration and chemotherapy resistance
《World Journal of Gastrointestinal Oncology》2025年第4期365-383,共19页Xiao-Fei Lu Hong-Wei Zhang Xiao Chang Yong-Ze Guo 
The study was reviewed and approved by institutional ethics board of Affiliated Hospital of Hebei Engineering University(No.:2024[K]005-01).
BACKGROUND Colon cancer represents a significant malignant neoplasm within the digestive system,characterized by a high incidence rate and substantial disease burden.The F-box protein 22(FBXO22)plays a role in forming...
关键词:Colorectal cancer F-box protein 22 BIOMARKER PROGNOSIS Tumor immunology 
Anoikis-related gene signature associates with the immune infiltration and predicts the prognosis of glioma patients
《Genes & Diseases》2025年第2期117-120,共4页Jianghua Lin Junbao Wang Junmiao Zhao Xinyi Wu Leiyu Hao Xiao Tan Lixue Yang Lei-Lei Wu Yuyang Xia Xiaoling Zhang Kaijun Zhao Yu'e Liu 
funded Pudong New Area Health Commission (PW2022A-28);Neuroscience Innovation and Development Research Project (YXJL-2022-00351-0183).
Glioma is the most aggressive and incurable brain tumor.1 Anoikis is programed apoptosis in which cells are detached from the cellular matrix and suspended to death.2 It plays a critical role in cancer progression.Can...
关键词:METASTASIS Cancer PATIENTS 
Alternative splicing of immune-related genes identifies breast cancer subtypes with differential immune cell infiltration
《Genes & Diseases》2025年第2期121-124,共4页Zhangxiang Zhao Yuquan Wang Zixin Jin Huiming Han Bo Chen Mingyue Liu Kaidong Liu Shuping Zhuang Haihai Liang Yunyan Gu 
supported by the National Key Research and Development Program of China (No.2023YFF1204600);the Guangdong Province Basic and Applied Basic Research Fund (China) (No.2022A1515110765);the National Natural Science Foundation of China (No.32270710);the Outstanding Youth Foundation of Heilongjiang Province of China (No.YQ2021H005).
Breast cancer,recognized as a foremost cause of mortality among women,is characterized by a complex immune microenvironment.Alternative splicing(AS)is a crucial process leading to diverse transcript variants.Studies h...
关键词:CANCER MORTALITY IMMUNE 
ARPC1A Promotes NSCLC Malignancy via Stimulating the Drug Resistance and Cell Migration
《BIOCELL》2025年第3期483-502,共20页Hongjuan Guo Dan Liu Ruyu Yan Tianjing Zhang Kecheng Zhou Minxia Liu 
supported by the Natural Science Foundation of Anhui Province(ML 2308085MC80);the Anhui Medical University Research and Innovation Talent Team(KZ).
Objectives:Non-small cell lung cancer(NSCLC)represents a formidable malignancy characterized by its marked metastatic potential and intrinsic resistance to therapeutic interventions.The identification of potential bio...
关键词:NSCLC ARPC1A drug resistance EMT immune infiltration dynamics 
Overexpression and clinicopathological significance of zinc finger protein 71 in hepatocellular carcinoma
《World Journal of Hepatology》2025年第2期182-199,共18页Kai Qin Dan-Dan Xiong Zhen Qin Ming-Jie Li Qi Li Zhi-Guang Huang Yu-Xing Tang Jian-Di Li Yan-Ting Zhan Rong-Quan He Jie Luo Hai-Quan Wang Shu-Qi Zhang Gang Chen Dan-Ming Wei Yi-Wu Dang 
Supported by Joint Project on Regional High Incidence Diseases Research of Guangxi Natural Science Foundation,No.2024GXNSFAA010057 and No.2024GXNSFAA010085;Natural Science Foundation of Guangxi,China,No.2022GXNSFBA035657;Guangxi Zhuang Autonomous Region Health Commission Self-Financed Scientific Research Project,No.Z20210764;Guangxi Zhuang Autonomous Region Administration of Traditional Chinese Medicine Scientific Research Project,No.GXZYA20230270 and No.GXZYA20240305;Advanced Innovation Teams and Xinghu Scholars Program of Guangxi Medical University(2022).
BACKGROUND Hepatocellular carcinoma(HCC)is one of the most prevalent and aggressive forms of liver cancer,with high morbidity and poor prognosis due to late diagnosis and limited treatment options.Despite advances in ...
关键词:Hepatocellular carcinoma Zinc finger protein 71 IMMUNOHISTOCHEMISTRY Enrichment analysis Immune infiltration 
The High Expression of EXOSC3 in OSCC is Associated with Poor Prognosis and Immune Infiltration
《Proceedings of Anticancer Research》2025年第1期52-61,共10页Yucunxi Liu Jianguo Liu 
Oral squamous cell carcinoma(OSCC)is the most common malignant tumor in the oral and maxillofacial region,primarily affecting the tongue,gingiva,oral cavity,buccal mucosa,and floor of the mouth.It exhibits high rates ...
关键词:EXOSC3 Oral squamous cell carcinoma Immune microenvironment Immune checkpoint 
Bioinformatic Analysis and Experimental Verification Reveals KBTBD6 as a Novel Prognostic Genes Associated with Immune Infiltration in OSCC
《Proceedings of Anticancer Research》2024年第6期31-45,共15页Dunhui Yang Huifei Lu Kang Li Xijia Wang Xiaorui Geng 
Zunyi Medical University Graduate Research Fund Project(Grant No.ZYK258)。
Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumors and has a poor prognosis. Kelch repeat and BTB domain-containing protein 6 (KBTBD6) regulates the cytoskeleton, cell proliferation, and ce...
关键词:KBTBD6 OSCC IMMUNE Immune checkpoint Prognosis 
A prognostic model for acute myeloid leukemia based on ferroptosis-related lncRNA and immune infiltration analysis
《Biophysics Reports》2024年第6期377-387,共11页Shuhan Liu Yingli Chen Qianzhong Li Zhiyu Fan Menglan Li Pengyu Du 
supported by grants from the National Natural Science Foundation of China(62361047,32160216)。
Acute myeloid leukemia(AML)is a rare tumor that invades the blood and bone marrow,it is rapidly progressive,highly aggressive,and difficult to cure.Studies have shown that long non-coding RNA(lncRNA)and ferroptosis pl...
关键词:Acute myeloid leukemia Ferroptosis Long non-coding RNA PROGNOSIS Immune infiltrates 
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