INFILTRATION

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Construction of a prognostic model based on the cuproptosis-related genes in pancreatic cancer
《Genes & Diseases》2025年第3期19-22,共4页Kaili Liao Yuxin Fu Shuman Guo Tingyi Qian Feifei Teng Yuhan Xu Bing Sun Hanqing Zhao Jingyan Zhang Ranhao Fan Jie Gao Xiaozhong Wang 
the Ethics Committee of the Second Affiliated Hospital of Nanchang University(approval numbers:(2023)CDYFYYLK(05e023)).
Pancreatic cancer(PC)is a commonly malignant tumor with a 5-year survival rate of only 10%.1 Cuproptosis is a newly discovered cell death mechanism closely associated with the development of tumors.This study mainly a...
关键词：immune infiltration marker genes comparing expression patterns construct prognostic model prognostic model cell death mechanism cuproptosis pancreatic cancer 
Utilization of cuproptosis-related lncRNAs to predict the prognosis of pancreatic cancer patients and explore their roles in immune cell infiltration and prognosis evaluation
《Genes & Diseases》2025年第3期39-41,共3页Kaili Liao Jinting Cheng Xiajing Yu Ziqian Liu Xue Zhang Yuxin Fu Wenyige Zhang Jie Liu Feifei Teng Yuxuan Xie Xiwen Yan Gaoquan Cao Bing Sun Hanqing Zhao Jingyan Zhang Xiaozhong Wang 
funded by the National Natural Science Foundation of China(No.82160405).
The prognosis of pancreatic cancer(PC)is difficult to predict1 and is extremely poor.2 Studies showed that cuproptosis was related to PC.The roles are not completely understood.It is considered that lncRNAs are closel...
关键词：pearson correlation analysis immune cell infiltration univariate cox regression analysis lncRNAs cuproptosis pancreatic cancer pancreatic cancer pc PROGNOSIS 
F-box protein 22: A prognostic biomarker for colon cancer associated with immune infiltration and chemotherapy resistance
《World Journal of Gastrointestinal Oncology》2025年第4期365-383,共19页Xiao-Fei Lu Hong-Wei Zhang Xiao Chang Yong-Ze Guo 
The study was reviewed and approved by institutional ethics board of Affiliated Hospital of Hebei Engineering University(No.:2024[K]005-01).
BACKGROUND Colon cancer represents a significant malignant neoplasm within the digestive system,characterized by a high incidence rate and substantial disease burden.The F-box protein 22(FBXO22)plays a role in forming...
关键词：Colorectal cancer F-box protein 22 BIOMARKER PROGNOSIS Tumor immunology 
Diagnostic value and immune infiltration characterization of WTAP as a critical m6A regulator in liver transplantation
《Hepatobiliary & Pancreatic Diseases International》2025年第2期138-146,共9页Shan-Shan Li Deng-Liang Lei Hua-Rong Yu Song Xiang Yi-Hua Wang Zhong-Jun Wu Li Jiang Zuo-Tian Huang 
supported by grants from Chongqing Re-search Performance Incentive and Guidance Project(No.cstc2022jxjl120032);Chongqing Technology Innovation and Application Development(Key Project,No.cstc2021jscx-gksb X0060)。
Background:RNA N6-methyladenosine(m6A)regulators are essential for numerous biological processes and are implicated in various diseases.However,the comprehensive role of m6A regulators in the context of liver transpla...
关键词：Ischemia-reperfusion injury Liver transplantation N6-methyladenosine WTAP 
Anoikis-related gene signature associates with the immune infiltration and predicts the prognosis of glioma patients
《Genes & Diseases》2025年第2期117-120,共4页Jianghua Lin Junbao Wang Junmiao Zhao Xinyi Wu Leiyu Hao Xiao Tan Lixue Yang Lei-Lei Wu Yuyang Xia Xiaoling Zhang Kaijun Zhao Yu'e Liu 
funded Pudong New Area Health Commission (PW2022A-28);Neuroscience Innovation and Development Research Project (YXJL-2022-00351-0183).
Glioma is the most aggressive and incurable brain tumor.1 Anoikis is programed apoptosis in which cells are detached from the cellular matrix and suspended to death.2 It plays a critical role in cancer progression.Can...
关键词：METASTASIS Cancer PATIENTS 
Alternative splicing of immune-related genes identifies breast cancer subtypes with differential immune cell infiltration
《Genes & Diseases》2025年第2期121-124,共4页Zhangxiang Zhao Yuquan Wang Zixin Jin Huiming Han Bo Chen Mingyue Liu Kaidong Liu Shuping Zhuang Haihai Liang Yunyan Gu 
supported by the National Key Research and Development Program of China (No.2023YFF1204600);the Guangdong Province Basic and Applied Basic Research Fund (China) (No.2022A1515110765);the National Natural Science Foundation of China (No.32270710);the Outstanding Youth Foundation of Heilongjiang Province of China (No.YQ2021H005).
Breast cancer,recognized as a foremost cause of mortality among women,is characterized by a complex immune microenvironment.Alternative splicing(AS)is a crucial process leading to diverse transcript variants.Studies h...
关键词：CANCER MORTALITY IMMUNE 
Effect of Ca addition on microstructure and properties of porous Mg−1Zn−1Sn alloy scaffold prepared via 3D printed Ti template-infiltration casting
《Transactions of Nonferrous Metals Society of China》2025年第4期1137-1154,共18页Lei-ting YU Hao LIU Peng-nan JIANG Shao-yuan LYU Yun ZHAO Wei LI Min-fang CHEN 
the financial support for this work from the National Natural Science Foundation of China(Nos.52171241,52373251,52201301,51801137);Natural Science Foundation of Tianjin City,China(No.22JCQNJC00750);Tianjin University of Technology Graduate Research Innovation Project,China(No.YJ2235)。
The Mg−1Zn−1Sn and Mg−1Zn−1Sn−0.2Ca alloy scaffolds were prepared via infiltration casting using 3D-printed Ti templates to achieve complete and accurate control of the pore structure.The results indicate that the act...
关键词：infiltration casting 3D-printed Ti template mechanical properties corrosion resistance BIOCOMPATIBILITY 
ARPC1A Promotes NSCLC Malignancy via Stimulating the Drug Resistance and Cell Migration
《BIOCELL》2025年第3期483-502,共20页Hongjuan Guo Dan Liu Ruyu Yan Tianjing Zhang Kecheng Zhou Minxia Liu 
supported by the Natural Science Foundation of Anhui Province(ML 2308085MC80);the Anhui Medical University Research and Innovation Talent Team(KZ).
Objectives:Non-small cell lung cancer(NSCLC)represents a formidable malignancy characterized by its marked metastatic potential and intrinsic resistance to therapeutic interventions.The identification of potential bio...
关键词：NSCLC ARPC1A drug resistance EMT immune infiltration dynamics 
CCL2-CCR2 axis in cardiovascular disease:research advances and challenges
《Science Bulletin》2025年第6期820-824,共5页Yang Yang Jiayan Li Jiayou Tang Bo Wang Jing Wang Xuezeng Xu Wangrui Lei Ying Cheng Liwen Liu 
supported by the National Natural Science Foundation of China(82270526,82070422,82200330,82071932,82371974,and 82272009);Key Medical Research Projects in Xi’an City(24YXYJ0010);Shaanxi Province Traditional Chinese Medicine Research and Innovation Talent Project(TZKN-CXRC-06);Research Plan Project of Shaanxi Institute of Basic Science(22JHQ053);Qinchuangyuan Traditional Chinese Medicine Innovation Research and Development Transformation Project(2022-QCYZH-036).
C-C motif chemokine ligand 2(CCL2)is a member of the chemokine family and is also known as monocyte chemoattractant protein-1.It is a crucial factor for regulating the migration and infiltration of various immune cell...
关键词：monocyte chemoattractant protein chemokine family cardiovascular disease CCL immune cells migration infiltration c chemokine ligand MONOCYTES 
Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies
《Neural Regeneration Research》2025年第3期779-793,共15页Guangyong Zhang Qing Yao Chubing Long Pengcheng Yi Jiali Song Luojia Wu Wei Wan Xiuqin Rao Yue Lin Gen Wei Jun Ying Fuzhou Hua 
supported by the National Natural Science Foundation of China,Nos.82060219,82271234;the Natural Science Foundation of Jiangxi Province,Nos.20212ACB216009,20212BAB216048;Jiangxi Province Thousands of Plans,No.jxsq2019201023;Youth Team Project of the Second Affiliated Hospital of Nanchang University,No.2019YNTD12003(all to FH)。
Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple rol...
关键词：blood–brain barrier MACROPHAGES MONOCYTES multiple sclerosis NEUROINFLAMMATION review therapy 
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