GENOME-WIDE

作品数:468被引量:1637H指数:17
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相关领域:生物学更多>>
相关作者:奥玛谢永芳南娟王玲舒坤贤更多>>
相关机构:华中农业大学东南大学北京大学中国科学院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>
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Genome-wide association analysis reveals regulatory genes for the metabolite synthesis of 2-acetyl-1-pyrroline in aromatic coconut(Cocos nucifera L.)
《Journal of Genetics and Genomics》2025年第2期179-188,共10页Hao Ding Xiang Lv Guangzhen Zhou Xiaomei Liu Xiwei Sun Jing Li Amjad Iqbal Yaodong Yang 
supported by the Major Science and Technology Project of Hainan Province(ZDKJ2021012);National Natural Science Foundation of China(32071805);the National Key Research and Development Program of China(2023YFD2200700)。
Coconut(Cocos nucifera L.)is a key tropical economic tree valued for its fruit flavor,particularly 2-acetyl-1-pyrroline(2AP),a vital aroma metabolite.To enhance high-aromatic coconut breeding efforts,it is essential t...
关键词:Aromatic coconut 2AP SNP Genome-wideassociation study(GWAS) Haplotype analysis 
The genome-wide meiotic recombination landscape in ciliates and its implications for crossover regulation and genome evolution被引量:1
《Journal of Genetics and Genomics》2024年第3期302-312,共11页Lu Fu Chen Gu Kazufumi Mochizuki Jie Xiong Wei Miao Guangying Wang 
supported by the Wuhan Branch,Supercomputing Center,Chinese Academy of Sciences,China;supported by the National Aquatic Biological Resource Center(NABRC);supported by the Bureau of Frontier Sciences and Education,Chinese Academy of Sciences(ZDBS-LY-SM026);the National Natural Science Foundation of China(32370457,32122015,32130011,31900316,and 31900339);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0480000);PJA3 grant of ARC Foundation(ARCPJA2021060003830);Equipes 2022 grant of Foundation Recherche Medicale(EQU202203014651).
Meiotic recombination is essential for sexual reproduction and its regulation has been extensively studied in many taxa.However,genome-wide recombination landscape has not been reported in ciliates and it remains unkn...
关键词:Meiotic recombination HOTSPOT Crossover interference Adaptive evolution 
Corrigendum to“CRISPR-detector:fast and accurate detection,visualization,and annotation of genome-wide mutations induced by genome editing events”[Journal of Genetics and Genomics(2023)563-572]
《Journal of Genetics and Genomics》2023年第10期813-813,共1页Lei Huang Dan Wang Haodong Chen Jinnan Hu Xuechen Dai Chuan Liu Anduo Li Xuechun Shen Chen Qi Haixi Sun Dengwei Zhang Tong Chen Yuan Jiang 
This corrigendum clarifies information in the article“CRISPR-detector:fast and accurate detection,visualization,and annotation of genomewide mutations induced by genome editing events”by Huang et al.(2023).In the fi...
关键词:al. Cor INSERTION 
CRISPR-detector:fast and accurate detection,visualization,and annotation of genome-wide mutations induced by genome editing events
《Journal of Genetics and Genomics》2023年第8期563-572,共10页Lei Huang Dan Wang Haodong Chen Jinnan Hu Xuechen Dai Chuan Liu Anduo Li Xuechun Shen Chen Qi Haixi Sun Dengwei Zhang Tong Chen Yuan Jiang 
supported by the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ13-YQ-095 and ZZXT201708);the Start-up Research Fund from BNU-HKBU United International College(UICR0700053-23).
The leading-edge CRISPR/CRISPR-associated technology is revolutionizing biotechnologies through genome editing.To track on/off-target events with emerging new editing techniques,improved bioinformatic tools are indisp...
关键词:Genome editing On/off-target Genetic background removal Structural variation 
Genome-wide analyses of nonsyndromic cleft lip with or without palate identify 20 new risk loci in the Chinese Han population
《Journal of Genetics and Genomics》2022年第9期903-905,共3页Bao Li Liang Yong Yafen Yu Yanqin Yu Qi Zhen Huiyao Ge Yiwen Mao Weiwei Chen Yanxia Yu Yirui Wang Zhuo Li Wencheng Fan Chang Zhang Xia Hu Ruixue Zhang Lu Cao Hao Liu Zhuan Bian Miao He Liangdan Sun 
funded by the National Natural Science Foundation of China(81970904 to MH,81970923 to ZB);Anhui Institute of Translational Medicine(ZHYX2020A005 to LS);the University Synergy Innovation Program of Anhui Province(GXXT-2020-064 to LS);Clinical medicine discipline construction project of Anhui Medical University(2021lcxk008 to LS);the National Key Research and Development Program(2016YFC1000505 to ZB)。
Orofacial clefts(OFCs),particularly cleft lip with or without cleft palate(CL/P)and cleft palate only(CPO),are among the most common birth defects in humans(Mossey et al.,2009;Dixon et al.,2011).The birth prevalence r...
关键词:al. PALATE DIXON 
Genome-wide selection and introgression of Chinese rice varieties during breeding
《Journal of Genetics and Genomics》2022年第5期492-501,共10页Jinyue Ge Junrui Wang Hongbo Pang Fei Li Danjing Lou Weiya Fan Ziran Liu Jiaqi Li Danting Li Baoxuan Nong Zongqiong Zhang Yanyan Wang Jingfen Huang Meng Xing Yamin Nie Xiaorong Xiao Fan Zhang Wensheng Wang Jianlong Xu Sung Ryul Kim Ajay Kohli Guoyou Ye Weihua Qiao Qingwen Yang Xiaoming Zheng 
supported by the National Key Research and Development Program of China(2016YFD0100301 to Z.X.M.);the National Natural Science Foundation of China(31670211 and31970237 to Z.X.M.);Sanya Yazhou Bay Science and Technology City(SKJC-2020-02-001 to Z.X.M.);the Central Public-interest Scientific Institution Basal Research Fund(S2021ZD01 to Z.X.M.);the Major Incubation Project of Shenyang Normal University(ZD20210 to P.H.B.);the Hundred Talent Program of Shenyang Normal University(SSDBRJH2002012 to P.H.B.)。
China is the largest rice-producing country,but the genomic landscape of rice diversity has not yet been clarified.In this study,we re-sequence 1070 rice varieties collected from China(400)and other regions in Asia(67...
关键词:RICE Genome selection INTROGRESSION Agronomic traits BREEDING 
Genome-wide meta-analysis identifies ten new psoriasis susceptibility loci in the Chinese population被引量:1
《Journal of Genetics and Genomics》2022年第2期177-180,共4页Weiwei Chen Wenjun Wang Liang Yong Qi Zhen Yafen Yu Huiyao Ge Yiwen Mao Lu Cao Ruixue Zhang Xia Hu Zhuo Li Yirui Wang Wencheng Fan Qiongqiong Xu Hui Zhang Shirui Chen Jing Wu Liangdan Sun 
supported by grants from the National Natural Science Foundation of China(81972927,81773313);Anhui Institute of Translational Medicine(ZHYX2020A005)。
Psoriasis is caused by many factors and is characterized by excessive proliferation of the epidermis and erythema with silver scales on the surface of the skin and concomitant with a variety of diseases(Griffiths et a...
关键词:PSORIASIS DISEASES 
Pathway analysis for genome-wide genetic variation data:Analytic principles,latest developments,and new opportunities被引量:1
《Journal of Genetics and Genomics》2021年第3期173-183,共11页Micah Silberstein Nicholas Nesbit Jacquelyn Cai Phil H.Lee 
supported by National Institutes of Health R00 MH101367 and R01 MH119243(to P.H.Lee)。
Pathway analysis,also known as gene-set enrichment analysis,is a multilocus analytic strategy that integrates a priori,biological knowledge into the statistical analysis of high-throughput genetics data.Originally dev...
关键词:Pathway analysis Set-based association analysis Gene-set enrichment analysis Genome-wide association study Multilocus association analysis 
Genome-wide evolution analysis reveals low CpG contents of fast-evolving genes and identifies antiviral microRNAs被引量:1
《Journal of Genetics and Genomics》2020年第1期49-60,共12页Wenhong Zu Hang Zhang Xun Lan Xu Tan 
supported by the National Natural Science Foundation of China (Grant No. 31670777);the China National Funds for Distinguished Young Scientists (Grant No. 31722030);the Beijing Advanced Innovation Center for Structural Biology to X.T.;the Tsinghua-Peking Joint Center for Life Sciences (Grant No. 61020100119);the National Thousand Young Talents Program of China (Grant No. 042021011) to X.L.
Noncoding RNAs(ncRNAs) play important roles in many biological processes and provide materials for evolutionary adaptations beyond protein-coding genes, such as in the arms race between the host and pathogen. However,...
关键词:Host-virus interaction Positive selection CPG DINUCLEOTIDE Noncoding RNA MicroRNA 
Mapping quantitative trait loci using binned genotypes被引量:1
《Journal of Genetics and Genomics》2019年第7期343-352,共10页Wen Yao Guangwei Li Yanru Cui Yiming Yu Qifa Zhang Shizhong Xu 
supported by the National Key Research and Development Program (2016YFD0100802);the National Science Foundation Collaborative Research grant (DBI-1458515)
Precise mapping of quantitative trait loci(QTLs)is critical for assessing genetic effects and identifying candidate genes for quantitative traits.Interval and composite interval mappings have been the methods of choic...
关键词:GENOME-WIDE association studies Linear mixed model POLYGENE PROXIMAL contamination QTL MAPPING 
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