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SPECTROMETRY: 作品数：461被引量：896H指数：12; 导出分析报告; 相关领域：理学生物学更多>>; 相关作者：姜山何明武绍勇石磊李世红更多>>; 相关机构：中国计量科学研究院中国原子能科学研究院吉林大学广西大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家质检总局科技计划项目国家教育部博士点基金更多>>

Chemical isotope labeling-assisted liquid chromatography-mass spectrometry enables sensitive and accurate determination of dipeptides and tripeptides in complex biological samples: 《Chinese Chemical Letters》2024年第11期284-289,共6页Feng-Qing Huang Yu Wang Ji-Wen Wang Dai Yang Shi-Lei Wang Yuan-Ming Fan Raphael N.Alolga Lian-Wen Qi; financially supported in part by the National Natural Science Fund of China for Distinguished Young Scholars(No.81825023);National Natural Science Foundation of China(No.82003979);Natural Science Foundation of Shanghai(No.23ZR1459100)。; Small peptides have attracted increasing attention for their unique features and diverse biological functions.Achieving rapid separation and accurate quantification,however,remains a challenge because of their low abu...; 关键词：Di/tripeptides Chemical derivatization Isotope labeling Liquid chromatography tandem mass SPECTROMETRY Biliary tract cancer

Thermal benzene activation by 3d transition metal(Sc-Cu) oxide cations: 《Chinese Chemical Letters》2020年第3期779-782,共4页Jiatong Cui Yue Zhao Ming Wang Shanshan Wang Jiabi Ma; supported by National Key R&D Program of China(No.2016YFC0203000);the National Natural Science Foundation of China(No.21503015);the Fundamental Research Funds for the Central Universities(Nos.22050205,2017CX01008)。; Considering the importance and complexity of benzene oxidation on mineral oxide aerosol surfaces in the atmosphere,gas-phase 3 d-transition metal oxide cations were used as models of active sites on mineral oxide aero...; 关键词：GAS-PHASE REACTIONS Transition metal OXIDE CATIONS BENZENE Mass SPECTROMETRY Ion-molecular reaction

Analytical methods for locating modifications in nucleic acids被引量：2: 《Chinese Chemical Letters》2019年第9期1618-1626,共9页Chubo Qi Jianghui Ding Bifeng Yuan Yuqi Feng; the National Key R&D Program of China (No. 2017YFC0906800);the National Natural Science Foundation of China (Nos. 21672166, 21635006, 21721005, 21728802) for the financial support; In addition to the canonical nucleobases, a variety of chemical modifications have been identified presence in nucleic acids. These modifications have been demonstrated to involve in regulating the spatiotemporal expr...; 关键词：Nucleic ACID MODIFICATION LOCATION Mapping Mass SPECTROMETRY SEQUENCING NANOMATERIAL

On-line trapping/capillary hydrophilic-interaction liquid chromatography/mass spectrometry for sensitive determination of RNA modifications from human blood被引量：1: 《Chinese Chemical Letters》2019年第3期553-557,共5页Chubo Qi Hanpeng Jiang Jun Xiong Bifeng Yuan Yuqi Feng; financially supported by the National Natural Science Foundation of China (Nos. 21522507, 21672166, 21728802, 21721005); RNA modification has recently been proposed to play important roles in biological regulation. The detection and quantification of RNA modifications generally are challenging tasks since most of the modifications exist...; 关键词：N^6-Methyladenosine 5-Methylcytosine Hydrophilic-interaction liquid chromatography CAPILLARY monolithic column Mass SPECTROMETRY

A high-performance bio-tissue imaging method using air flow-assisted desorption electrospray ionization coupled with a high-resolution mass spectrometer被引量：3: 《Chinese Chemical Letters》2019年第2期461-464,共4页Yiwei Lv Tiegang Li Chengan Guo Chenglong Sun Fei Tang Luojiao Huang Zhigang Luo Xin Li Ruiping Zhang Qingce Zang Jiuming He Zeper AbliZ; supported by the National Instrumentation Program (No. 2016YFF0100304);the National Natural Science Foundation of China(Nos. 21335007, 81773678);the CAMS Innovation Fund for Medical Sciences(No. 2016-12 M-1-009);PUMC Youth Fund and the Fundamental Research Funds for the Central Universities(No. 3332015177); Mass spectrometry imaging (MSI) technology can simultaneously obtain the spatial distribution of thousands of chemical compounds and has unique advantages compared to other techniques that allow mapping the surface of...; 关键词：MASS SPECTROMETRY imaging Air flow-assisted desorption electrospray ionization HIGH-RESOLUTION MASS SPECTROMETRY Endogenous metabolites Bio-tissue imaging

Construction of on-line supercritical fluid extraction with reverse phase liquid chromatography–tandem mass spectrometry for the determination of capsaicin被引量：3: 《Chinese Chemical Letters》2019年第1期99-102,共4页Naoki Hamada Yuki Hashi Satoshi Yamaki Yanli Guo Lin Zhang Haifang Li Jin-Ming Lin; supported by the National Natural Science Foundation of China (No. 21621003); A novel on-line system composed of supercritical fluid extraction(SFE), dilution line and reverse phase liquid chromatography/mass spectrometry(RPLC/MS) was constructed for on-line extraction and reverse phase separat...; 关键词：SUPERCRITICAL fluid extraction Liquid chromatography-mass SPECTROMETRY COLUMN-SWITCHING system CAPSAICIN

Analysis of the binding sites with NL-101 to amino acids and peptides by HPLC/MS/MS被引量：4: 《Chinese Chemical Letters》2019年第1期103-106,共4页Lingzi Dai Nian Guo Yaqin Liu Shanshan Shen Qiufu Ge Yuanjiang Pan; supported by the National Natural Science Foundation of China (Nos. 21327010, 21372199); The binding between NL-101, a novel nitrogen mustard anti-cancer drug, with amino acids and peptides has been investigated by high performance liquid chromatography electrospray tandem mass spectrometry(HPLC/ESI-MS/MS...; 关键词：High-performance liquid chromatography/ tandem mass SPECTROMETRY NL-101 AMINO ACIDS PEPTIDES Binding sites

Deciphering nucleic acid modifications by chemical derivatization-mass spectrometry analysis被引量：2: 《Chinese Chemical Letters》2019年第1期1-6,共6页Meng-Dan Lan Bi-Feng Yuan Yu-Qi Feng; supported by the National Key R&D Program of China (No. 2017YFC0906800);the National Natural Science Foundation of China (Nos. 21522507, 21672166, 21635006 and 21721005); Now increasing chemical modifications are discovered on genomic DNA and RNA. Up to date, more than150 chemical modifications are identified in nucleic acids. These chemical modifications do not change the sequence of ...; 关键词：MASS SPECTROMETRY ANALYSIS Chemical DERIVATIZATION DNA MODIFICATION RNA MODIFICATION

Synthesis and photo activity of phenylazonaphthalene peptide nucleic acid monomers被引量：1: 《Chinese Chemical Letters》2008年第7期807-810,共4页Jin Du Li Miao Chen Sheng Liu Hao Bo Zhang Zhi Lu Liu; the National Nature Science Foundation of China (No.20473106);the Innovation Group Project (No.50421502);973 project (No.2007CB607605)of the Chinese Ministry of Science & Technology.; Phenylazonaphthalene peptide nucleic acid （PNA） monomers were successfully synthesized, and their photoisomerization was examined. The new PNA monomers showed reversible trans-cis isomerization with UVand visible li...; 关键词：Peptide nucleic acid Phenylazonaphthalene PHOTOISOMERIZATION UV-vis absorption spectrometry Fluorescence spectrometry

Application of Simultaneous Technique of Capillary Zone Electrophoresis Photothermal Interference Spectrometry for Monitoring Chelating Reaction of Light Rare Earth with Tribromoarsenazo: 《Chinese Chemical Letters》1997年第5期425-426,共2页Yong Gang HU Yan Zhuo DENG Jie Ke CHENG(Department of Chenustry, Center of Analysis and Testing, Wuhan Umversity, Wuhan 430072); A novel high sensihtity, small-volume photothermal intheence detector has beenintroduced for capillap zone electrophoresis separation analysis. The utility of thes sdriulboconstecheque for momtomp chelating reachon of...; 关键词：Application of Simultaneous Technique of Capillary Zone Electrophoresis Photothermal Interference Spectrometry for Monitoring Chelating Reaction of Light Rare Earth with Tribromoarsenazo

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