ENTEROVIRUSES

作品数：24被引量：130H指数：6
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Seroprevalence of neutralizing antibodies against HFMD associated enteroviruses among healthy individuals in Shanghai,China,2022
《Virologica Sinica》2024年第4期694-698,共5页Jiayu Wang Wencheng Wu Wei Wang Jingyi Zhang Jianwei Xiao Mingyi Cai Jiaying Guo Run Li Shuangli Zhu Wanju Zhang Min Chen Zheng Teng 
supported by the key research project of Three-Year Initiative Plan for Strengthening Public Health System Construction in Shanghai(Grant no:GWVI-3,GWVI-11.1-09);approved by the Ethics Committees of Shanghai Municipal Center for Disease Control and Prevention(Ethics Number,2023-44)。
Dear Editor,Hand,foot and mouth disease(HFMD)is one of the most common infectious diseases,particularly in the Asia-Pacific region.In the past two decades,HFMD rises to prominence for its heavy burden,with over one mi...
关键词：ENTEROVIRUS HFMD 
Integration of HiBiT into enteroviruses:A universal tool for advancing enterovirus virology research被引量：1
《Virologica Sinica》2024年第3期422-433,共12页Rui Yu Xiaohong Li Peng Zhang Minghao Xu Jitong Zhao Jingjing Yan Chenli Qiu Jiayi Shu Shuo Zhang Miaomiao Kang Xiaoyan Zhang Jianqing Xu Shuye Zhang 
supported by the National Natural Science Foundation of China(grant nos.82002135 and 82172250).
The utilization of enteroviruses engineered with reporter genes serves as a valuable tool for advancing our understanding of enterovirus biology and its applications,enabling the development of effective therapeutic a...
关键词：ENTEROVIRUS Infectious clones Reporter genes LUCIFERASE Drug screening 
Stability and infectivity of enteroviruses on dry surfaces:Potential for indirect transmission control被引量：1
《Biosafety and Health》2023年第6期339-345,共7页Pichamon Sittikul Pimolpachr Sriburin Jittraporn Rattanamahaphoom Warisa Nuprasert Nipa Thammasonthijarern Janjira Thaipadungpanit Weerawan Hattasingh Nathamon Kosoltanapiwat Pilaipan Puthavathana Supawat Chatchen 
Hand,foot,and mouth disease(HFMD)is a contagious disease mainly occurring in young children,and outbreaks commonly occur among young children in the Asia–Pacific region including Thailand.Moreover,the World Health Or...
关键词：ENTEROVIRUSES EV-A71 Genomic RNA HAND FOOT and mouth disease MTT assay STABILITY 
Antiviral Drugs(Synthetic Small Molecule Inhibitors and Nature Drugs)Against EV71 in Enteroviruses:Advances and Perspectives
《Clinical Complementary Medicine and Pharmacology》2023年第4期19-33,共15页Yuwei Liu Yuan Xi Likai Ji Quan Shen Wen Zhang Mengzhu Xue 
supported financially by the National Natural Science Foundation of China(82101630).
Background:Enterovirus 71(EV71)is a major virus that causes hand-foot-mouth disease.In cases of infants and young children,EV71 infection has been associated with severe neurological disease and potentially fatal syst...
关键词：Hand-foot-mouth disease Enterovirus 71 RECEPTORS Natural drugs Protease inhibitors 
Laboratory diagnosis of nonpolio enteroviruses:A review of the current literature被引量：1
《Biosafety and Health》2023年第2期112-119,共8页Tarek Itani Vladislav Chalapa Aleksandr Semenov Aleksandr Sergeev 
This study was funded by the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing,grant ID 121041500041−1.
Infections by nonpolio enteroviruses(EVs)are highly prevalent,particularly among children and neonates,where they may cause substantial morbidity and mortality.Laboratory diagnosis of these viral infections is importa...
关键词：Nonpolio enteroviruses Virus isolation Nucleic acid amplification tests Sanger sequencing Next-generation sequencing 
A one-step reverse-transcription recombinase aided PCR assay for the rapid and sensitive detection of human enteroviruses被引量：1
《Biosafety and Health》2023年第2期126-131,共6页Xiuli Sun Huanhuan Lu Yanqing Tie Mengchuan Zhao Ruiqing Zhang Zhenlu Sun Guohao Fan Fengyu Li Fengyu Tian Yaxin Hu Mengyi Zhang Xinxin Shen Xuejun Ma Zhishan Feng 
This work was supported by the National Key R&D Program of China(2021YFC2301102);National Natural Science Foundation of China(82202593);the Central Guidance on Local Science and Technology Development Fund of Hebei Province(216Z7713G).
Human enteroviruses(HEVs)include many different types that cause a wide range of diseases,and an effective method of genus-level identification has therefore significant clinical implications.However,quantitative real...
关键词：Human enteroviruses Nucleic acid detection RT-RAP assay 
EV713C protease cleaves host anti-viral factor OAS3 and enhances virus replication被引量：6
《Virologica Sinica》2022年第3期418-426,共9页Xiaolei Zhou Li Tian Jian Wang Baisong Zheng Wenyan Zhang 
supported by funding from the National Key R&D Program of China(2021YFC2301900 and 2301904);National Natural Science Foundation of China(81930062);Health Commission of Jilin Province(2020J059);the Key Laboratory of Molecular Virology,Jilin Province(20102209)。
The global spread of enteroviruses(EVs)has become more frequent,severe and life-threatening.Intereron(IFN)I has been proved to control EVs by regulating IFN-stimulated genes(ISG)expression.20-50-oligoadenylate synthet...
关键词：ENTEROVIRUSES EV71 3C protease CLEAVAGE Anti-viral factor OAS3 
Ectopic Expression of TRIM25 Restores RIG-I Expression and IFN Production Reduced by Multiple Enteroviruses 3Cpro被引量：4
《Virologica Sinica》2021年第6期1363-1374,共12页Huimin Xiao Jingliang Li Xu Yang Zhaolong Li Ying Wang Yajuan Rui Bin Liu Wenyan Zhang 
The study was supported by the National Natural Science Foundation of China(No.81672004 and 81930062);the Science and Technology Department of Jilin Province(20190101003JH);the Key Laboratory of Molecular Virology,Jilin Province(20102209)。
Enteroviruses(EVs) 3C proteins suppress type I interferon(IFN) responses mediated by retinoid acid-inducible gene I(RIG-I), while an E3 ubiquitin ligase, tripartite motif protein 25(TRIM25)-mediated RIG-I ubiquitinati...
关键词：3C proteins RIG-I TRIM25 Innate immunity Enteroviruses(EVs) 
Genetic Variation of Multiple Serotypes of Enteroviruses Associated with Hand, Foot and Mouth Disease in Southern China被引量：18
《Virologica Sinica》2021年第1期61-74,共14页Yonghong Zhou Le Van Tan Kaiwei Luo Qiaohong Liao Lili Wang Qi Qiu Gang Zou Ping Liu Nguyen To Anh Nguyen Thi Thu Hong Min He Xiaoman Wei Shuanbao Yu Tommy Tsan-Yuk Lam Jie Cui H.Rogier van Doorn Hongjie Yu 
supported by the National Science and Technology Major Project of China(No.2018ZX10201001-010,No.2017ZX10103009-005,No.2018ZX10713001-007);the National Natural Science Fund for Distinguished Young Scholars of China(No.81525023);the National Natural Science Foundation of China(No.81473031);the Program of Shanghai Academic/Technology Research Leader(No.18XD1400300);the Li Ka Shing Oxford Global Health Programme(No.B9RST00-B900.57);the Chinese Preventive Medicine Association(No:20101801);supported by CAS Pioneer Hundred Talents Program
Enteroviruses(EVs)species A are a major public health issue in the Asia–Pacific region and cause frequent epidemics of hand,foot and mouth disease(HFMD)in China.Mild infections are common in children;however,HFMD can...
关键词：Enteroviruses(EVs) HAND foot and mouth disease(HFMD) Enterovirus A71(EV-A71) Coxsackievirus A16(CVA16) Coxsackievirus A6(CVA6) 
National Epidemiology and Evolutionary History of Four Hand, Foot and Mouth Disease-Related Enteroviruses in China from 2008 to 2016被引量：44
《Virologica Sinica》2020年第1期21-33,共13页Xuemin Fu Zhenzhou Wan Yanpeng Li Yihong Hu Xia Jin Chiyu Zhang 
supported by the TOTAL foundation,and the Grants from the National Science and Technology Major Project of China(2017ZX10103009-002);the "One Belt One Road" Project(153831KYSB20170043)of the Chinese Academy of Sciences;the133 Project of Institut Pasteur of Shanghai,CAS.
Hand, foot and mouth disease(HFMD) is a major public health concern in China. The most predominant enteroviruses that cause HFMD have traditionally been attributed to enterovirus A71(EVA71) and coxsackievirus A16(CVA1...
关键词：ENTEROVIRUS Hand foot and MOUTH disease(HFMD) Molecular EPIDEMIOLOGY Evolution Genotype 
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