NEUTROPHILS

作品数：230被引量：934H指数：16
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相关作者：刘艳芳孙汭田志刚魏海明徐皓亮更多>>
相关机构：中国医学科学院北京协和医学院第二军医大学中国人民解放军第三〇二医院中国科学技术大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>
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  • 期刊=Signal Transduction and Targeted Therapyx
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Neutrophils are shaped by the tumor microenvironment:novel possibilities for targeting neutrophils in cancer被引量：1
《Signal Transduction and Targeted Therapy》2024年第5期1788-1790,共3页Carlos Silvestre-Roig Lydia Kalafati Triantafyllos Chavakis 
The research of the authors is supported by the Deutsche Forschungsgemeinschaft(SFB-TRR 332).The figure was created with Biorender.com.
In a recent paper published in Science,Ng et al.provide seminal insights into the process through which neutrophils are reprogrammed by the tumor environment,leading to a convergent transition from different neutrophi...
关键词：al. NEUTROPHILS TUMOR 
Sell^(hi) neutrophils: a key to triumph in cancer therapy
《Signal Transduction and Targeted Therapy》2023年第12期5568-5569,共2页Ekaterina Pylaeva Jadwiga Jablonska 
support by the Open Access Publication Fund of the University of Duisburg-Essen;supported by the Deutsche Forschungsgemeinschaft(DFG/JA-2461/7-1 and CRC TRR332 project A05 to J.J.).
In a recent study published in Cell,Gungabeesoon and colleagues demonstrated that a specific subpopulation of neutrophils,characterized by a distinct Sell^(hi)(CD62L^(hi))phenotype with an interferon gene signature,ac...
关键词：cancer INTERFERON NEUTROPHILS 
Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCII^(hi) neutrophils被引量：6
《Signal Transduction and Targeted Therapy》2023年第9期4305-4319,共15页Teng Ma Yu Tang Taolin Wang Yang Yang Yige Zhang Ruihuan Wang Yongxin Zhang Yi Li Mingbo Wu Miao Tang Xueli Hu Chaoyu Zou Yuan Ren Huan Liu Qianhua Zhang Heyue Li Min Wu Jing Li Xikun Zhou 
This work was supported by the National Natural Science Foundation of China(No.81922042,82172285,82241049,82072999 and 82273320);the 1·3·5 project of excellent development of discipline of West China Hospital of Sichuan University(No.ZYYC21001);the Innovation Research Project of Sichuan University(No.2022SCUH0029);the CAMS Innovation Fund for Medical Sciences(CIFMS,2019-I2M-5-004).
Breast cancer can metastasize to various organs,including the lungs.The immune microenvironment of the organs to be metastasized plays a crucial role in the metastasis of breast cancer.Infection with pathogens such as...
关键词：METASTASIS LUNG BREAST 
Tumor neutrophils ferroptosis:a targetable immunosuppressive mechanism for cancer immunotherapy被引量：1
《Signal Transduction and Targeted Therapy》2023年第3期879-880,共2页Songtao Du Furong Zeng Guangtong Deng 
We would like to thank Qian Zhou for generating the figure used in this paper and thank Editage(www.editage.cn)for English language editing.The images were created with BioRender.com.This work was supported by the National Natural Science Foundation of China(Grant Nos.82103183 to F.Z.,82102803,82272849 to G.D.);National Natural Science Foundation of Hunan Province(Grant Nos.2022JJ40767 to F.Z.,2021JJ40976 to G.D.).
In a recent study published in Nature,Kim et al.demonstrated that ferroptosis of polymorphonuclear myeloid-derived suppressor cells(PMN-MDSCs)causes immune suppression in cancer,1 highlighting ferroptosis inhibition a...
关键词：IMMUNOTHERAPY CANCER al. 
Bitter receptor TAS2R138 facilitates lipid droplet degradation in neutrophils during Pseudomonas aeruginosa infection被引量：4
《Signal Transduction and Targeted Therapy》2021年第7期2154-2163,共10页Qinqin Pu Kai Guo Ping Lin Zhihan Wang Shugang Qin Pan Gao Colin Combs Nadeem Khan Zhenwei Xia Min Wu 
The authors thank the National Institutes of Health for Grants R01 AM 138203,R01 All09317-01 Al,and AI097532-01A1 for M.W.,as well as P20 GM113123 and P20 GM103442 for Imaging,Histology,and Flow Cytometry Core Facility.
Bitter receptors function primarily in sensing taste,but may also have other functions,such as detecting pathogenic organisms due to their agile response to foreign objects.The mouse taste receptor type-2 member 138(T...
关键词：thereby MAINTAIN MIGRATE 
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