DRUG-INDUCED

作品数:120被引量:422H指数:11
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相关领域:医药卫生更多>>
相关作者:魏群吴和珍骆静尹江华郭礼和更多>>
相关机构:北京师范大学中国科学院上海生命科学研究院浙江大学首都医科大学更多>>
相关期刊:更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Non-alcoholic fatty liver disease and drug induced liver injury:A metabolic storm waiting to happen
《World Journal of Hepatology》2025年第3期8-12,共5页Vanessa Pamela Salolin Vargas Marisa Gasbarra Ernesto Calderon-Martinez Yash R Shah Dushyant Singh Dahiya Mauricio Garcia Saenz de Sicilia 
In this editorial,we comment on the article by Zhao et al which highlighted how patients having nonalcoholic fatty liver disease(NAFLD)were more susceptible to drug-induced lung injury(DILI).This article looked at the...
关键词:Nonalcoholic fatty liver disease Drug-induced lung injury Clinical chara-cteristics Prognosis 
Opioid-induced pancreatitis:A case study
《Journal of Acute Disease》2024年第6期220-222,共3页Anuka Koul Jaspreet Kaur Sahil Attri Navneet Arora 
Rationale:Opioids,the class of drugs,frequently used for pain relief in acute pancreatitis are known to act as a dual-edged sword.They are capable of causing acute pancreatitis though very rare.Patient’s Concern:A 45...
关键词:Acute pancreatitis Drug-induced pancreatitis OPIOID TOXICOLOGY 
Prometheus 2.0: drug-induced liver regeneration arising被引量:1
《Cell Research》2024年第8期541-542,共2页Jan S.Tchorz 
In a recent publication in Cell,a multidisciplinary academic drug discovery team,with its spin-off HepaRegeniX,published a first-in-class small molecule MKK4 inhibitor(HRX215)with remarkable efficacy in multiple precl...
关键词:DRUG LIVER CLINICAL 
Drug-induced entero-colitis due to interleukin-17 inhibitor use;capsule endoscopic findings and pathological characteristics:A case report
《World Journal of Gastroenterology》2023年第32期4912-4919,共8页Keita Saito Kiichiro Yoza Shinichiro Takeda Yoshihiro Shimoyama Ken Takeuchi 
BACKGROUND Interleukin-17(IL-17)inhibitors are known to cause exacerbation or new onset of inflammatory bowel disease upon administration.However,few reports have described characteristic endoscopic and histopathologi...
关键词:Interleukin-17 inhibitor Ixekizumab Drug-induced entero-colitis Capsule endoscopy Case report 
MicroRNA-29a-3p Prevents Drug-Induced Acute Liver Failure through Inflammation-Related Pyroptosis Inhibition被引量:1
《Current Medical Science》2023年第3期456-468,共13页Dan-dan XIANG Jing-tao LIU Zi-biao ZHONG Yan XIONG Hong-yan KONG Hai-jing YU Ting PENG Jia-quan HUANG 
This project was supported by grants from the National Science and Technology Major Project(No.2014ZX10005001 and No.2018ZX10302204-001);Chen Xiaoping Development Foundation(No.CXPJJH12000002-2020032).
Objective Little is known about the role of microRNA-29a-3p(miR-29a-3p)in inflammation-related pyroptosis,especially in drug-induced acute liver failure(DIALF).This study aimed to identify the relationship between miR...
关键词:acute liver failure microRNA-29a-3p PYROPTOSIS INFLAMMATION 
COVID-19-related liver injury:Focus on genetic and drug-induced perspectives
《World Journal of Virology》2023年第1期53-67,共15页Deepak Parchwani Amit D Sonagra Sagar Dholariya Anita Motiani Ragini Singh 
BACKGROUND Empirical use of potentially hepatotoxic drugs in the management of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection is considered as one of the major etiopathogenetic factors for liver ...
关键词:SARS-CoV-2 Liver injury Genetic prospective Drug-induced liver injury Prognosis COVID-19 
Drug-induced autoimmune hepatitis:A minireview被引量:11
《World Journal of Gastroenterology》2022年第24期2654-2666,共13页Chin Kimg Tan Danielle Ho Lai Mun Wang Rahul Kumar 
Drug-induced autoimmune hepatitis(DIAIH)is a specific phenotype of druginduced liver injury that may lead to the devastating outcome of acute liver failure requiring liver transplantation.Drugs implicated in DIAIH inc...
关键词:Drug-induced liver injury Drug-induced autoimmune hepatitis Autoimmune hepatitis REVIEW 
Drug-induced Fatty Liver Disease:Pathogenesis and Treatment被引量:1
《Journal of Clinical and Translational Hepatology》2021年第5期731-737,共7页Tea Omanovic Kolaric Vjera Nincevic Lucija Kuna Kristina Duspara Kristina Bojanic Sonja Vukadin Nikola Raguz-Lucic George Y Wu Martina Smolic 
The study was funded by a grant from Croatian Ministry of Science and Education(dedicated to multi-year institutional funding of scientific activity at the J.J.Strossmayer University of Osijek,Osijek,Croatia,under grant number:IP10-MEFOS-2019 to MS);Support from the Herman Lopata Chair in Hepatitis Research is also gratefully acknowledged(to GYW).
Metabolic dysfunction-associated fatty liver disease(commonly known as MAFLD)impacts global health in epidemic proportions,and the resulting morbidity,mortality and economic burden is enormous.While much attention has...
关键词:Metabolic dysfunction-associated fatty liver disease Drug-induced liver injury Reactive oxygen species Free fatty acids PHARMACOGENETICS 
Induced pluripotent stem cells as an innovative model to study drug induced pancreatitis
《World Journal of Gastroenterology》2021年第35期5796-5802,共7页Elena Genova Gabriele Stocco Giuliana Decorti 
Supported by Italian Ministry of Health(IRCCS Burlo Garofolo),No.RC 7_2014.
Drug-induced pancreatitis is a gastrointestinal adverse effect concerning about 2%of drugs.The majority of cases are mild to moderate but severe episodes can also occur,leading to hospitalization or even death.Unfortu...
关键词:Induced pluripotent stem cells Therapy personalization Patient-specific cells Drug-induced pancreatitis THIOPURINES Inflammatory bowel disease 
Mitochondrial-triggered immune responses mechanistically connect drug-induced steatohepatitis and cardiomyopathy associated with nonalcoholic steatohepatitis
《Cellular & Molecular Immunology》2021年第8期2078-2080,共3页Haoran Wang Sananda Pai Shun Ishiyama Xin Guo Wei Dong Gao Lakshmi Santhanam Kathy Gabrielson Dolores B.Njoku 
The work was supported in part by the Johns Hopkins School of Medicine Stimulating and Advancing ACCM Research(StAAR)award program.
In our prior publication[1],we elucidated IL-33-dependent mechanisms that regulate drug-induced liver injury.In this commentary,we mechanistically connected IL-33-dependent drug-induced steatohepatitis with nonalcohol...
关键词:drug HEPATITIS drugs 
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