supported by the National Key Research and Development Projects,Nos.2022 YFC3602400,2022 YFC3602401(to JX);the Project Program of National Clinical Research Center for Geriatric Disorders(Xiangya Hospital),No.2020LNJJ16(to JX);the National Natural Science Foundation of China,No.82271369(to JX)。
Hemorrhagic transformation is a major complication of large-artery atheroscle rotic stroke(a major ischemic stro ke subtype)that wo rsens outcomes and increases mortality.Disruption of the gut microbiota is an importa...
Natural Science Foundation of China(No.81771264);Qingdao Annual Medical Scientific Research Guidance Plan(2020-WJZD181 and 2020-WJZD197);Qingdao Science and Technology Demonstration and Guidance Project for benefiting the people(22-3-7-smjk-3-nsh)
Background:Endovascular treatment(EVT)for acute ischemic stroke with an occlusion of the M1 segment due to intracranial atherosclerotic severe stenosis(ICASS)remains challenging.This study aimed to evaluate the safety...
Ischemic stroke resulting from atherosclerosis(particularly in the carotid artery)is one of the major subtypes of stroke and has a high incidence of death.Disordered lipid homeostasis,lipid deposition,local macrophage...
Purpose: To evaluate the safety and efficacy of Enterprise stent in the treatment of symptomatic complex intracranial atherosclerotic stenosis. Methods and materials: 20 complex cases among 53 patients with symptomati...
grants of Natural Science Foundation of China(81271536,61271132 and 81361120402);Philips Healthcare.
Background:Carotid atherosclerotic plaque is identified as one of the main sources of ischaemic stroke.However,the prevalence of carotid high-risk atherosclerotic plaque in Chinese patients with ischaemic cerebrovascu...
Objective To study the role of risk factors associated with hemodynamics in patients with intracranial artery stenosis.Methods Eighteen patients with local stenosis of middle cerebral artery were recruited in this stu...
supported by the National Natural Science Foundation of China (No. 81072945)
Summary: Glycoprotein (GP) Ibα ectodomain shedding has important implications for thrombosis and hemostasis. A disintegrin and metalloproteinase 17 (ADAM17) was identified to play an essen- tial role in agonist ...
the National Natural Science Foundation of China(No 30271509).
Aim:To study the protein and mRNA expressions of pro-inflammatory and anti- inflammatory cytokines in the brain of rats with atherosclerosis(AS)and the effects of Ginkgo biloba extract(GbE)on expressions of cytokines....
Objective: To explore the frequency and significance of ApoE gene polymorphisms in Chinese patients with atherosclerotic cerebral infarction (ACI). Methods: Polymerase chain reaction and gene sequencing, single nucleo...