AGE-RELATED

作品数：152被引量：373H指数：10
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相关作者：陈梅梅颜奕熊浩谢立科王楠更多>>
相关机构：首都医科大学西安外国语大学北京语言大学中国中医科学院眼科医院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金广东省自然科学基金更多>>
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Age-related secretion of grancalcin by macrophages induces skeletal stem/progenitor cell senescence during fracture healing
《Bone Research》2024年第1期122-136,共15页Nan-Yu Zou Ran Liu Mei Huang Yu-Rui Jiao Jie Wei Yangzi Jiang Wen-Zhen He Min Huang Yi-Li Xu Ling Liu Yu-Chen Sun Mi Yang Qi Guo Yan Huang Tian Su Ye Xiao Wei-Shan Wang Chao Zeng Guang-Hua Lei Xiang-Hang Luo Chang-Jun Li 
This work was supported by the National Key R&D Program of China(Project No.2019YFA0111900 to C.J.L.and Y.J.,2022YFC3601900 to G.H.L.,2022YFC3601903 to X.H.L.,and 2022YFC3601905);the National Natural Science Foundation of China(Grant Nos.82261160397,82272560,81922017 to C.J.L.and 81930022,91749105 to X.H.L.);the NSFC/RGC Joint Research Scheme,the Research Grants Council(UGC)of the Hong Kong Special Administrative Region and the National Natural Science Foundation of China(NSFC/RGC Project No.N_CUHK483/22 to Y.J.);the Hunan Provincial Science and Technology Department(2023JJ30896 to C.J.L.);the Key Research and Development Program of Hunan Province(2022SK2023 to C.J.L.);the Science and Technology Innovation Program of Hunan Province(2023RC1027 to C.J.L.,2022RC1009 to J.W,and 2022RC3075 to C.Z.).
Skeletal stem/progenitor cell(SSPC)senescence is a major cause of decreased bone regenerative potential with aging,but the causes of SSPC senescence remain unclear.In this study,we revealed that macrophages in calluse...
关键词：healing UNION SENESCENCE 
The roles of bone remodeling in normal hematopoiesis and age-related hematological malignancies被引量：1
《Bone Research》2023年第2期273-291,共19页Hengwei Zhang Jane LLiesveld Laura MCalvi Brea CLipe Lianping Xing Michael WBecker Edward MSchwarz Shu-Chi A.Yeh 
supported by awards from the National Institute of Health R21AR069789&R01 AG059775(to LX),R01 AG076786&R01 AG079556;The Henry and Marilyn Taub Foundation;the Edward P.Evans Foundation;the Mangurian Foundation;the National Aeronautics and Space Administration(to LMC);NIH R21 AR081050,R01 AR056702,P30 AR069655&P50 AR072000(to EMS);University of Rochester Aging Institute and the Dresner MDS foundation(to SY)。
Prior research establishing that bone interacts in coordination with the bone marrow microenvironment(BMME)to regulate hematopoietic homeostasis was largely based on analyses of individual bone-associated cell populat...
关键词：REMODELING HOMEOSTASIS LIKELY 
Fighting age-related orthopedic diseases: focusing on ferroptosis被引量：16
《Bone Research》2023年第1期1-20,共20页Qin Ru Yusheng Li Wenqing Xie Yilan Ding Lin Chen Guodong Xu Yuxiang Wu Fudi Wang 
National Natural Science Foundation of China (82071970,81874030, 82072506, 92268115, and 31930057);National Key R&D Program of China(2019YFA0111900 and 2018YFA0507802);Innovation-Driven Project of Central South University (2020CX045);Key Program of Health Commission of Hunan Province(20201902);Young Talents Project of Hubei Provincial Health Commission(WJ2021Q053);Science and Technology Innovation Program of Hunan Province (No.2021RC3025);Innovation Project for Postgraduate Students of Central South University (2021zzts1024);Science and Technology Innovation Project of Jianghan University (2021kjzx008)。
Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation and lipid peroxidation. It is closely related to multiple biological processes, including iron metabolism, polyunsaturated fatt...
关键词：METABOLISM DISEASES PEROXIDATION 
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