supported by the National Natural Science Foundation of China(U22A20272,82173807,82170497)。
Parkinson's disease(PD)is one of the most common neurodegenerative diseases.The loss of dopaminergic(DAergic)neurons in the substantia nigra and the decrease of dopamine(DA)levels accelerate the process of PD.L-Ergoth...
supported by the National Natural Science Foundation of China(32072646,31772373,and 32001832).
Ergothioneine is a natural amino acid with powerful antioxidant activity.Previous studies have demonstrated that ergothioneine can increase the lifespan of Drosophila melanogaster and Caenorhabditis elegans,and enhanc...
supported by grants from the National Key R&D Program of China(No.2018YFA0903200 to C.Z.);the National Natural Science Foundation of China(Nos.32270032 and 32070038 to C.Z.,No.32000029 to L.C.).
Ergothioneine,Ovothiol,and Selenoneine are sulfur/selenium-containing histidine-derived natural products widely distributed across different organisms.They exhibit significant antioxidant properties,making them as pot...
This work was supported by National Key Research and Development Program of China(2019YFC1606400).
L-Ergothioneine(L-EGT)possesses excellent antioxidant activity and has been used in the food,pharmaceuticals and cosmetics industries.In this study,a new efficient and sensitive ultra-performance liquid chromatography...
funded by the National Natural Science Foundation of China(Nos.32072185,31870042,and 31972204);the Natural Science Foundation of Liaoning Province(2020-MS-277).
Ergothioneine(EGT)is a natural sulfur-containing amino acid with potent antioxidant and cytoprotective ac-tivities.In this study,the oxidation tolerance of 23 different Rhodotorula strains were screened with hydrogen ...
supported by the National Key Research and Development Program of China (2021YFC2100800);the National Natural Science Foundation of China (31970085);the Jiangsu Province Natural Science Fund for Distinguished Young Scholars (BK20200025).
Gene regulation by trans-acting small RNAs(sRNAs)has considerable advantages over other gene regulation strategies.However,synthetic sRNAs mainly take natural sRNAs(MicC or SgrS)as backbones and comprise three functio...
According to the market research company Euromonitor, China’s anti-aging market recorded sales of RMB 64.6 billion in 2020, and the figure surged to over RMB 80 billion in 2021, up by 20% roughly. Another market rese...
Financial support from the National Natural Science Foundation of China(Nos.81502942,81522050,30825044);the National Science and Technology Project of China(Nos.2012ZX09301002-002,2011ZX09307-002-01)
Gastrolatathioneine (1), an unusual natural product derived from ergothioneine, a fungal amino acid containing an imidazole-2-thione moiety, was isolated from an aqueous extract of "tian ma" (the Gastrodia elata ...
Ever since the appearance of atmospheric oxygen,organisms have needed ways to protect themselves from damage caused by oxidative stress.Glutathione(GSH,Fig.1A)is the dominant organothiol in eukarya to detoxify product...
Supported by In part grants from the Ministry of Agriculture,Forestry,and Fisheries of Japan(Rural Biomass Research Project,BM-D2300)and Fisheries Research Agency
A novel selenium-containing compound,selenoneine,has been isolated as the major form of organic selenium in the blood and tissues of tuna.Selenoneine harbors a selenium atom in the imidazole ring,2-selenylNα,Nα,Nα-...