INTERFERON-Α

作品数：73被引量：302H指数：10
导出分析报告
相关领域：医药卫生更多>>
相关作者：卢桥生邢同京侯金林骆抗先冯筱榕更多>>
相关机构：中国人民解放军第一军医大学内蒙古医学院附属医院华中科技大学中南大学更多>>
相关期刊：《世界最新医学信息文摘》《Frontiers of Medicine》《Frontiers of Chemical Science and Engineering》《Journal of Wuhan University of Technology(Materials Science)》更多>>
相关基金：国家自然科学基金吉林省卫生厅科研基金国家教育部博士点基金国家高技术研究发展计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Interferon-αstimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis
《Military Medical Research》2025年第2期184-203,共20页Kai-Wei Jia Ren-Qi Yao Yi-Wen Fan Ding-Ji Zhang Ye Zhou Min-Jun Wang Li-Yuan Zhang Yue Dong Zhi-Xuan Li Su-Yuan Wang Mu Wang Yun-Hui Li Lu-Xin Zhang Ting Lei Liang-Chen Gui Shan Lu Ying-Yun Yang Si-Xian Wang Yi-Zhi Yu Yong-Ming Yao Jin Hou 
National Key Research and Development Program of China(2023YFC2505900);National Natural Science Foundation of China(92269204,82171755,92369106,82171749,82171811,82073184);Military Outstanding Youth Program(2020QN06119,01-SWK JYCJJ07,23SWAQ53);Program of Leading Talents in Shanghai,and Shanghai Shuguang Program(20SG39)。
Background Liver ischemia/reperfusion(I/R)injury is usually caused by hepatic inflow occlusion during liver surgery,and is frequently observed during war wounds and trauma.Hepatocyte ferroptosis plays a critical role ...
关键词：Ischemia/reperfusion(I/R) DExH-box helicase 58(DHX58) Glutathione peroxidase 4(GPX4) m6A modification YT521-B homology domain containing 2(YTHDC2) 
Macrophage phagocytosis of SARS-CoV-2-infected cells mediates potent plasmacytoid dendritic cell activation被引量：2
《Cellular & Molecular Immunology》2023年第7期835-849,共15页O.García-Nicolás A.Godel G.Zimmer A.Summerfield 
Early and strong interferon type I (IFN-I) responses are usually associated with mild COVID-19 disease, whereas persistent orunregulated proinflammatory cytokine responses are associated with severe disease outcomes. ...
关键词：SARS-CoV-2 COVID-19 Monocyte-derived macrophages Plasmacytoid dendritic cell INTERFERON-Α Inflammatory cytokines 
Clinical spectrum and currently available treatment of typeⅠinterferonopathy Aicardi-Goutières syndrome被引量：4
《World Journal of Pediatrics》2023年第7期635-643,共9页Giovanni Battista Dell'Isola Gianluca Dini Kaleb Logan Culpepper Katherin Elizabeth Portwood Pietro Ferrara Giuseppe Di Cara Alberto Verrotti Mauro Lodolo 
Universita degli Studi di Perugia within the CRUI-CARE agreement.
Background Aicardi-Goutières syndrome(AGS)is a genetically determined disorder with a variable phenotype.Since the original description of AGS,advances in gene sequencing techniques have resulted in a significant bro...
关键词：Aicardi-Goutieres syndrome Immunosuppressive drugs INTERFERON-Α NEUROINFLAMMATION Systemic lupus erythematosus 
CK1α upregulates the IFNAR1 expression to prompt the anti-HBV effect of type Ⅰ IFN in hepatoma carcinoma cells
《Virologica Sinica》2022年第6期894-903,共10页Jing Xiong Yanjun Jiang Jinru Zhang Yanmeng Chen Yuan Hu 
supported by the National Key Research and Development Program of China(2018YFE0107500);the Natural Science Foundation Project of Science and Technology Agency of Chongqing YuZhong District(20200122)to Hu Yuan;a Natural Science Foundation Project of CQ CSTC(cstc2021jcyj-msxmX0276)to Chen YanMeng
Casein kinase 1α(CK1α) mediates the phosphorylation and degradation of interferon-α/β receptor 1(IFNAR1) in response to viral infection. However, how CK1α regulates hepatitis B virus(HBV) replication and the anti...
关键词：Hepatitis B virus(HBV) Casein kinase 1α(CK1α) Interferon-α/βreceptor 1(IFNAR1) Interferon-α(IFN-α) 
Heterogeneity of immune control in chronic hepatitis B virus infection:Clinical implications on immunity with interferon-αtreatment and retreatment被引量：1
《World Journal of Gastroenterology》2022年第40期5784-5800,共17页Guo-Qing Yin Ke-Ping Chen Xiao-Chun Gu 
Hepatitis B virus(HBV)infection is a global public health issue.Interferon-α(IFN-α)treatment has been used to treat hepatitis B for over 20 years,but fewer than 5%of Asians receiving IFN-αtreatment achieve function...
关键词：Hepatitis B virus Chronic Functional cure HETEROGENEITY IMMUNITY Immune control INTERFERON-Α RETREATMENT 
Strategies for improving the efflcacy of immunotherapy in hepatocellular carcinoma被引量：6
《Hepatobiliary & Pancreatic Diseases International》2022年第5期420-429,共10页Ying Zhu Lun-Xiu Qin 
supported by grants from the National Natural Science Foundation of China(81902390);the Major Program of National Natural Science Foundation of China(91959203);the Key Program of the National Natural Science Foundation of China(81930074)。
Primary liver cancer,mainly hepatocellular carcinoma(HCC),is the sixth most diagnosed cancer and third leading cause of cancer-related death globally.Recently,immunotherapies such as immune checkpoint inhibitors(ICIs)...
关键词：Hepatocellular carcinoma Tumor microenvironment Immune checkpoint inhibitors INTERFERON-Α Programmed death receptor 1 
The combination of PD-1 blockade with interferon-αhas a synergistic effect on hepatocellular carcinoma被引量：15
《Cellular & Molecular Immunology》2022年第6期726-737,共12页Ying Zhu Mo Chen Da Xu Tian-En Li Ze Zhang Jian-Hua Li Xiang-Yu Wang Xin Yang Lu Lu Hu-Liang Jia Qiong-Zhu Dong Lun-Xiu Qin 
This work was supported by the National Natural Science Foundation of China(81902390 and 81902952);the National Key Research and Development Program of China(2017YFC1308604).
Background The efficacy of immune checkpoint inhibitors(ICIs),such as programmed cell death protein-1(PD-1)or its ligand 1(PD-L1)antibody,in hepatocellular carcinoma(HCC)is limited,and it is recommended that they be c...
关键词：Hepatocellular carcinoma Tumor microenvironment PD-1 Pegylated interferon-α T-cell exhaustion 
DNA methylation profile of a hepatosplenic gamma/delta T-cell lymphoma patient associated with response to interferon-α therapy
《Cellular & Molecular Immunology》2021年第5期1332-1335,共4页Jaydeep Bhat Anke KBergmann Silvio Waschina Christoph Nerl Christoph Kaleta Reiner Siebert Ole Ammerpohl Dieter Kabelitz 
supported by the Deutsche Forschungsgemeinschaft(DFG)through the Cluster of Excellence“Inflammation-at-Interfaces”EXC306-PN and EXC306-PM(D.K.,O.A.and C.K.);the Werner-und-Klara-Kreitz Foundation(JB).
The 2–5%γδT cells in healthy human peripheral blood recognize nonpeptide antigens,in contrast toαβT cells.1 DistinctγδT-cell malignancies have been identified,with hepatosplenic T-cell lymphoma(γδ-HSTL)being ...
关键词：hepato SPLENIC INTERFERON 
Expression levels of interferon-α receptor,interferon-stimulated gene factor 3,double-stranded RNA-activated protein kinase and ribonuclease L in chronic hepatitis B patients treated with interferon
《China Medical Abstracts(Internal Medicine)》2021年第1期50-51,共2页YANG Qian 
Objective To investigate the expression levels of interferon-α receptor (IFNAR),interferon-stimulated gene factor 3 (ISGF3),double-stranded RNA-activated protein kinase (PKR) and ribonuclease L (RNase L) in patients ...
关键词：INTERFERON patients Nanchang 
Taurocholic acid inhibits the response to interferon-αtherapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8^(+)T and NK cell function被引量：4
《Cellular & Molecular Immunology》2021年第2期461-471,共11页Zhen Xun Jinpiao Lin Qingqing Yu Can Liu Jinlan Huang Hongyan Shang Jianhui Guo Yuchen Ye Wennan Wu Yongbin Zeng Songhang Wu Siyi Xu Tianbin Chen Jing Chen Qishui Ou 
We thank all the staff and patients of our hospital for the provision of the samples used in this study.This work was supported by the National Natural Science Foundation of China(Grant numbers 81971996,82030063,81672101,81702073);the Joint Funds for the Innovation of Science and Technology,Fujian Province(Grant number 2019Y9017).
Pegylated interferon-alpha (PegIFNα) therapy has limited effectiveness in hepatitis B e-antigen (HBeAg)-positive chronic hepatitis B (CHB) patients. However, the mechanism underlying this failure is poorly understood...
关键词：Bile acids Pegylated interferon Hepatitis B virus Immune cells Mechanism 
全选清除导出
共8页<12345678>
检索报告 对象比较 聚类工具 使用帮助 返回顶部