云南高校图书馆联盟文献共享服务平台- INTERFERON-Β

INTERFERON-Β: 作品数：17被引量：71H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：汪受传更多>>; 相关机构：南京中医药大学中国科学院大学更多>>; 相关期刊：《World Journal of Hepatology》《Journal of Integrative Agriculture》《Acta Biochimica et Biophysica Sinica》《Cellular & Molecular Immunology》更多>>; 相关基金：国家自然科学基金广东省自然科学基金福建省自然科学基金国家教育部博士点基金更多>>

A novel short transcript isoform of chicken IRF7 negatively regulates interferon-βproduction: 《Journal of Integrative Agriculture》2023年第7期2213-2220,共8页MA Yu-chen CHEN Hua-yuan GAO Shen-yan ZHANG Xiao-zhan LI Yong-tao YANG Xia ZHAO Jun WANG Zeng; supported by the grants from the National Natural Science Foundation of China(32002259);the Natural Science Foundation of Henan Province,China(202300410198).; Type I interferon(IFN-I)provides an important first line to protect avian species against pathogens invasion.IFN regulatory factor 7(IRF7)has been identified as the most important regulator for both DNA and RNA virus-...; 关键词：chIRF7 chIRF7 isoform negative regulation IFN-Β

Therapeutic effect of Qinghuayin(清化饮)against chronic atrophic gastritis through the inhibition of toll or interleukin-1 receptor domain-containing adaptor inducing interferon-β signaling pathway被引量：5: 《Journal of Traditional Chinese Medicine》2022年第2期221-226,共6页HE Youcheng YAO Xiaoling LI Sihan ZHOU Hongjian XU Ruoying ZHENG Rong XIAO Wendi SU Ning LIN Ping HUANG Minghan; Supported by Natural Science Foundation of Fujian Province(Based on NLRP3 Inflammatory Body/Caspase-1-mediated Gastric Epithelial Cell Death to Explore the Molecular Mechanism of Qinghua Decoction in the Treatment of Chronic Atrophic Gastritis,No.2020J01253)。; OBJECTIVE:To examine the efficacy of Qinghuayin(清化饮,QHY)in rat chronic atrophic gastritis(CAG)models and explored the molecular mechanism of QHY in treating CAG.METHODS:In total,65 Wistar rats were randomly divided...; 关键词：gastritis atrophic toll-like receptor 4 interleukin-6 interleukin-8 toll or interleukin-1 receptor domain-containing adaptor inducing interferon-β Qinghuayin

Increased cGAS/STING signaling components in patients with Mooren's ulcer被引量：4: 《International Journal of Ophthalmology(English edition)》2021年第11期1660-1665,共6页Ya-Ni Zhang Yan-Ling Dong Wen-Pei Hao Xiao-Fei Bai Xia Qi Ting Liu Xiao-Tong Sun Chao Wei Xiao-Lin Qi; Supported by National Natural Science Foundation of China(No.81900907);the Young and Middle-Aged Scientists Research Awards Fund of Shandong Province(No.ZR2017BH004)。; AIM:To explore the expression of cGAS/STING signaling components in Mooren’s ulcer(MU).METHODS:Samples were obtained from ten MU patients,and eight residual corneal-scleral rings of healthy donor corneas for controls...; 关键词：cGAS/STING signaling interferon regulatory factor 3 Mooren’s ulcer INTERFERON-Β

Toll-like receptor 3(TLR3)regulation mechanisms and roles in antiviral innate immune responses被引量：15: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2021年第8期609-632,共24页Yujuan CHEN Junhong LIN Yao ZHAO Xianping MA Huashan YI; supported by the National Key R&D Program of China(No.2018YFD0501705);the Chongqing Basic Research Program(No.cstc2018jcyj AX0615);the Fundamental Research Funds for the Central Universities(Nos.XDJK2018C059 and XDJK2018C060),China。; Toll-like receptor 3(TLR3)is a member of the TLR family,mediating the transcriptional induction of type I interferons(IFNs),proinflammatory cytokines,and chemokines,thereby collectively establishing an antiviral host ...; 关键词：Toll-like receptor 3(TLR3) Toll-interleukin-1 receptor(TIR)-domain-containing adaptor-inducing interferon-β(TRIF) Innate immune Antiviral response

Shiqi herbal tea reduces the susceptibility to H1N1 influenza virus in stressed mice: 《TMR Modern Herbal Medicine》2021年第1期44-52,共9页Guo Xie Zhuo Luo Lu-Ping Tang Li-Hang Zhang Li-Hua Peng Ling Jin Hiroshi Kurihara Jin-Le Cheng Yi-Fang Li Rong-Rong He; This work was financially supported,in part,by Science and Technology Project of Zhongshan(2013A3FC0253);Scientific Research Team Training Project in University of Electronic Science and Technology of China,Zhongshan Institute(No.412YT02);Natural Science Foundation of Guangdong Province-the Ph.D.Startup and Vertical Collaboration Project(2018030310186).; Objective:It is well known that stress plays a critical role in immune response and susceptibility to diseases.Among many stressors,restraint stress has been shown to suppress immune function and increase susceptibili...; 关键词：ShiQi herbal tea Restraint stress H1N1 virus C5A INTERFERON-Β SUSCEPTIBILITY

Novel insights into stress-induced susceptibility to influenza:corticosterone impacts interferon-βresponses by Mfn2-mediated ubiquitin degradation of MAVS被引量：7: 《Signal Transduction and Targeted Therapy》2020年第1期782-793,共12页Zhuo Luo Li-Fang Liu Ying-Nan Jiang Lu-Ping Tang Wen Li Shu-Hua Ouyang Long-Fang Tu Yan-Ping Wu Hai-Biao Gong Chang-Yu Yan Shan Jiang Yu-Hui Lu Tongzheng Liu Zhenyou Jiang Hiroshi Kurihara Yang Yu Xin-Sheng Yao Yi-Fang Li Rong-Rong He; supported,in part,by Natural Science Foundation of China(grant numbers 81622050,81573675,U1801284,81673709,81873209);National Key Research and Development Program of China(grant number 2017YFC1700404);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(grant number 2017BT01Y036)and GDUPS(2019);the Guangdong Science and Technology Foundation for Distinguished Young Scholars(grant number 2017A030306004);the Youth Top-notch Talent Support Program of Guangdong Province(2016TQ03R586);the Program of Hong Kong Scholar(XJ2016017);the Science and Technology Program of Guangzhou(grant number 201903010062).; Although stress has been known to increase the susceptibility of pathogen infection,the underlying mechanism remains elusive.In this study,we reported that restraint stress dramatically enhanced the morbidity and mort...; 关键词：INFLUENZA UBIQUITIN MAVS

Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier被引量：2: 《Cellular & Molecular Immunology》2019年第2期178-194,共17页Aisha Nazli Sara Dizzell Muhammad Atif Zahoor Victor H Ferreira Jessica Kafka Matthew William Woods Michel Ouellet Ali A Ashkar Michel J Tremblay Dawn ME Bowdish Charu Kaushic; by grants from the Canadian Institutes of Health Research(CIHR)Operating Grant FRN 126019(to CK);CIHR Team Grant on Mucosal Immunology of HIV Vaccine Development FRN 138657(to CK);the Ontario HIV Treatment Network(OHTN)Applied HIV Research Chair AHRC 779(to CK);VHF was supported by CIHR Banting Scholarship.; More than 40%of HIV infections occur via female reproductive tract(FRT)through heterosexual transmission.Epithelial cells that line the female genital mucosa are the first line of defense against HIV-1 and other sexua...; 关键词：antiviral response genital epithelium HIV-1 IFN-β innate immunity IRF-3 mucosal barrier TLR2

Elevated expression of EBV and TLRs in the brain is associated with Rasmussen's encephalitis被引量：3: 《Virologica Sinica》2017年第5期423-430,共8页Xin Wang Yisong Wang Dong Liu Peigang Wang Dongying Fan Yuguang Guan Tianfu Li Guoming Luan Jing An; the National Natural Science Foundation of China (81471957, 81571275, 81671971, and 81701992);the Beijing Municipal Natural Science Foundation (7144217);the Scientific Research Common Program of Beijing Municipal Commission of Education (KM201610025001); Rasmussen's encephalitis(RE) is a rare pediatric neurological disorder, the etiology of which remains unclear. It has been speculated that the immunopathogenesis of RE involves damage to neurons, which eventually lead...; 关键词：Rasmussen’s encephalitis(RE) Epstein-Barr virus(EBV) Toll-Like receptor(TLR) TIR-domain-containing adapter-inducing interferon-β(TRIF) epilepsy

Maillard reaction and immunogenicity of protein therapeutics: 《World Journal of Immunology》2016年第1期19-38,共20页Rositsa Tsekovska Angelina Sredovska-Bozhinov Toshimitsu Niwa Ivan Ivanov Roumyana Mironova; The recombinant DNA technology enabled the produ-ction of a variety of human therapeutic proteins. Accumulated clinical experience, however, indicates that the formation of antibodies against such proteins is a genera...; 关键词：Maillard reaction Glycation Advanced glycation end products Protein therapeutics INTERFERON-Β IMMUNOGENICITY

TOLL样受体TRIF信号因子与RSV关系的研究进展被引量：2: 《世界中西医结合杂志》2014年第8期897-900,共4页谢秀春汪受传; 国家自然科学基金项目(No.81072840);高等学校博士点专项科研基金(No.20103237110003); 呼吸道合胞病毒(respiratory syncytial virus,RSV)是婴幼儿急性下呼吸道感染最常见和最重要的病毒病原,尤其是肺炎和毛细支气管炎。Toll样受体(Toll-like receptors,TLRs)是近年来发现在抗感染及免疫反应起到重要作用的受体蛋白,可广...; 关键词：呼吸道合胞病毒(respiratory syncytial virus RSV) Toll样受体(Toll-like receptors TLRs) 接头蛋白(TIR-domain-containing adaptor inducing interferon-β TRIF)

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