AXONEME

作品数:4被引量:2H指数:1
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相关领域:生物学更多>>
相关期刊:《Science China(Life Sciences)》《Acta Biochimica et Biophysica Sinica》《Journal of Life Sciences》《Journal of Genetics and Genomics》更多>>
相关基金:霍英东教育基金国家自然科学基金国家重点基础研究发展计划更多>>
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Homozygous deleterious variants in MYCBPAP induce asthenoteratozoospermia involving abnormal acrosome biogenesis, manchette structure and sperm tail assembly in humans and mice
《Science China(Life Sciences)》2025年第3期777-792,共16页Yiling Zhou Chaofeng Tu Charles Coutton Jianan Tang Shixiong Tian Shuyan Tang Guillaume Martinez Dapeng Zhou Célia Tebbakh Jiaxiong Wang Raoudha Zouari Xuehai Zhou Selima Fourati Ben Mustapha Xuemei Wang Bangguo Wu Xinyan Geng Shuang Liu Li Jin Huijuan Shi Yue-Qiu Tan Pierre FRay Lingbo Wang Xiaoyu Yang Feng Zhang Chunyu Liu 
supported by the National Natural Science Foundation of China(32288101,32100480,32370654,82271638,32322017);the Innovative Research Team of High-Level Local Universities in Shanghai(SHSMU-ZDCX20212200);Shanghai Hospital Development Center Foundation(SHDC12023121);the outstanding Youth Foundation of Hunan Provincial Natural Science Foundation of China(2023JJ20080).
Asthenoteratozoospermia is a common cause of male infertility.To further define the genetic causes underlying asthenoteratozoospermia,we performed whole-exome sequencing in a cohort of Han Chinese men with asthenotera...
关键词:male infertility asthenoteratozoospermia MYCBPAP acrosome biogenesis MANCHETTE AXONEME 
Bi-allelic mutations in DNAH7 cause asthenozoospermia by impairing the integrality of axoneme structure被引量:2
《Acta Biochimica et Biophysica Sinica》2021年第10期1300-1309,共10页Xiaoli Wei Yanwei Sha Zijie Wei Xingshen Zhu Fengming He Xiaoya Zhang Wensheng Liu Yifeng Wang Zhongxian Lu 
This work was supported by the grants from the National Natu-ral Science Foundation of China(Nos.82071697 and 82001616);the Medical and Health Guidance Project of Xiamen(No.3502Z20199140).
Asthenozoospermia is the most common cause of male infertility.Dynein protein arms play a crucial role in the motility of both the cilia and flagella,and defects in these proteins generally impair the axoneme structur...
关键词:ASTHENOZOOSPERMIA whole-exome sequencing DNAH7 bi-allelic mutation 
RSBP15 interacts with and stabilizes dRSPH3 during sperm axoneme assembly in Drosophila
《Journal of Genetics and Genomics》2019年第6期281-290,共10页Ya Wang Rui Xu Yiwei Cheng Haowei Cao Zibin Wang Tianyu Zhu Jiayin Jiang Hao Zhang Chang Wang Lin Qi Mingxi Liu Xuejiang Guo Juan Huang Jiahao Sha 
supported by the National Basic Research Program of China (2016YFA0500903, 2016YFA0503300, and 2017YFA0103803);the National Natural Science Foundation of China (31530047 and 81771641);the Fok Ying Tung Education Foundation (161037);the 333 Project of Jiangsu Province (BRA2016386);the Program for Distinguished Talents of Six Domains in Jiangsu Province (YY-019)
Flagellum in sperm is composed of over 200 different proteins and is essential for sperm motility. In particular, defects in the assembly of the radial spoke in the flagellum result in male infertility due to loss of ...
关键词:RSBP15 RSPH3 FLAGELLUM Radial SPOKE DROSOPHILA 
Impact of Selenium on Microtubules Polymarisation of Spermatozoa of Endosulfan Exposed Swiss Albino Mice
《Journal of Life Sciences》2011年第2期132-135,共4页Ranjit Kumar Jitendra Kumar Singh Mohammad Ali Arun Kumar 
Pesticide plays a vital role in agricultural, industrial and residemial pest control. In recent years the ‘pesticide problem' has been the focus of public interest because these chemicals have a very important role ...
关键词:SPERMATOZOA SELENIUM MICROTUBULES dynein arm nexin AXONEME depolymerisation Swiss albino mice 
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