supported by the National Natural Science Foundation of China(32070800)。
Mammalian embryogenesis begins with a totipotent zygote.Blastocyst-like structures can be captured by aggregated cells with extended pluripotent properties in a three-dimensional(3D)culture system.However,the efficien...
Objective:To detect common chromosomal aneuploidy variations in embryos from couples undergoing assisted reproductive technology and preimplantation genetic screening and their possible associations with embryo qualit...
Dear Editor,Time-lapse videography of human embryos allows for the easy visualization of the embryos without removing them from the protective environment of the incubator[1],the measurement of various morphokinetic(q...
Studying the early function of essential genes is an Here, we established a method for rapidly inducing important and challenging problem in developmental biology. CRISPR-Cas9-mediated mutations in one blastomere of t...
supported by the China Agriculture Research System (CARS-37);the Agricultural Science and Technology Innovation Program, China (ASTIP-IAS06-2015)
The objective of this study was to establish an efficient system of producing early monozygotic twin bovine embryos in vitro using the blastomere separation and coculture technique. In this study, early eight-cell emb...
Capsule: Although embryos with synchronous blastomere cleavage showed higher post-thaw survival rates, pregnancy rates did not differ. Thus, embryos with all cleavage patterns may be safely cryopreserved. Objective: T...
supported by Grants (20060102A1022) from State 863 projects;Key projects of Science and Technology Commission of Shanghai (09ZR1419000)
Objective To investigate whether isolated blastomeres of discarded human embryos could develop into blastocysts cultured in vitro without zona pellucida. Methods Total discarded 60 embryos, which were not suitable for...
The derso-ventral axis of Xenopus embryo is established after fertilization. Blastula stage blastomeres acquire different identities as they have inherited different maternal materials which distribute radial symmetri...