PHYTOHEMAGGLUTININ

作品数：7被引量：11H指数：2
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相关领域：医药卫生更多>>
相关作者：张维政更多>>
相关机构：广东药学院四川大学更多>>
相关期刊：《Cellular & Molecular Immunology》《Food Quality and Safety》《Acta Biochimica et Biophysica Sinica》《Chinese Medical Sciences Journal》更多>>
相关基金：国家自然科学基金更多>>
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Innovations in measuring and mitigating phytohemagglutinins,a key food safety concern in beans
《Food Quality and Safety》2024年第1期1-11,共11页吕晨泽 房智慧 杨素 宁康 徐敏 Arnaud Buhot Yanxia Hou 胡培雅 徐沛 
the National Natural Science Foundation of China(Nos.32201254 and 32302545);the Basic Public Welfare Research Program of Zhejiang Province(No.LTGN23C020003);the State Key Laboratory for Managing Biotic and Chemical Treats to the Quality and Safety of Agro-products(No.2021DG700024-KF202403),China.
Phytohemagglutinin(PHA)is a seed storage protein and a type of lectin originally discovered in the common bean(Phaseolus vulgaris)for its blood-agglutinating effect.Due to its interactions with gut epithelia and diges...
关键词：PHYTOHEMAGGLUTININ common bean food safety BREEDING quantifcation. 
Correlations between phytohemagglutinin response and leukocyte profile,and bactericidal capacity in a wild rodent被引量：2
《Integrative Zoology》2015年第3期302-310,共9页Zhiqiang ZHANG Zhijun ZHAO 
This study was supported by a Key Project of Natural Science of the Anhui Province Department of Education,China(KJ2011A114);supported by the State Key Laboratory of Integrated Management of Pest Insects and Rodents,Institute of Zoology,The Chinese Academy of Sciences(ChineseIPM1001)to ZZQ.
phytohemagglutinin(PHA)-induced swelling is widely used to investigate cell-mediated and innate immunity across different vertebrate taxa.However,its physiological mechanism is still an open question due to the comple...
关键词：Cricetulus barabensis NEUTROPHILS PHYTOHEMAGGLUTININ serum bactericidal capacity striped hamster 
DNA Damage Response in Resting and Proliferating Peripheral Blood Lymphocytes Treated by Camptothecin or X-ray被引量：2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2011年第2期147-153,共7页田铭 冯永东 闵江 龚万军 肖薇 李小兰 陶德定 胡俊波 龚建平 
supported by grants from Program 973 from Ministry of Science;Technology of China (Nos. 2004CB518705, 2009CB5218702);the National Natural Sciences Foundation of China (Nos. 30872472, 30800569)
DNA damage response （DDR） in different cell cycle status of human peripheral blood lymphocytes （PBLs） and the role of H2AX in DDR were investigated. The PBLs were stimulated into cell cycle with phytohemagglutinin...
关键词：DNA double strand breaks PHYTOHEMAGGLUTININ peripheral blood lymphocytes γH2AX DNA damage response 
Comparative study on modeccin- and phytohemagglutinin （PHA）-induced secretion of cytokines and nitric oxide （NO） in RAW264.7 cells被引量：3
《Acta Biochimica et Biophysica Sinica》2011年第1期52-60,共9页Daekyung Kim Yasuhiro Yamasaki Zedong Jiang Yuki Nakayama Tomohiro Yamanishi Kenichi Yamaguchi Tatsuya Oda 
The effects of cytotoxic lectins, modeccin and phytohe- magglutinin （PHA） on mouse macrophage cell line RAW264.7 was studied by detecting the induction of inflammatory mediators. Results showed that modeccin induced...
关键词：modeccin PHA TNF-α G-CSF nitric oxide 
The Effect of Anti-Human CD134 Monoclonal Antibody on Phytohemagglutinin-Induced mRNA Expression of Perforin in Peripheral Blood Mononuclear Cells被引量：2
《Cellular & Molecular Immunology》2005年第6期467-471,共5页Ming Li~1 Yuanchao Zhang~(1,2) ~1Department of Rheumatology and Immunology,Shandong Provincial Hospital,Shandong University,Jinan 250021,China ~2Department of Rheumatology and Immunology,Shandong Provincial Hospital,Shandong University,Jinan 250021,Shandong,China. 
CD134, a member of the tumor necrosis factor receptor superfamily, plays a crucial role in T cell survival. In this study, peripheral blood mononuclear cells （PBMCs） stimulated with phytohemagglutinin （PHA, 50 μg...
关键词：CD134 PERFORIN PHYTOHEMAGGLUTININ 
EFFECTS OF β-ENDORPHIN ON PHYTOHEMAGGLUTININ-INDUCED LYMPHOCYTE PROLIFERATION AND MOUSE PLAQUE-FORMING CELL RESPONSE VIA AN OPIOID RECEPTOR MECHANISM
《Chinese Medical Sciences Journal》1994年第4期245-247,共3页林嘉友 鲁刚 翁佳玉 
The effects of opioid peptides on iminune responses were investigated. It was found that β-endorphin (β-END) can depress proliferative responses to PHA in rat splenocytes but enhance those in mice, and it could also...
关键词：lymphocyte transformation Β-ENDORPHIN NALOXONE 
PHA（phytohemagglutinin）毒性实验研究被引量：2
《广东药学院学报》1994年第4期258-259,共2页麦佩瑜 廖仕元 张维政 
利用凝集素能令精子凝集从而失去与卵结合的能力，研究ＰＨＡ外用避孕药，对其安全性评估是必须的。用常规方法检测，结果小鼠腹腔给药ＬＤ５０为１３５６．４ｍｇ／ｋｇ，属低毒；致突变性各项指标显示阴性；致畸试验中则胎鼠身长所受...
关键词：凝集素 致突变 致畸 
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