ANTIANDROGEN

作品数:10被引量:50H指数:2
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相关领域:医药卫生生物学更多>>
相关期刊:《Acta Pharmacologica Sinica》《Asian Journal of Andrology》《Cell Research》《Cancer Drug Resistance》更多>>
相关基金:国家自然科学基金更多>>
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Role of prostate cancer stem-like cells in the development of antiandrogen resistance被引量:1
《Cancer Drug Resistance》2022年第2期459-471,共13页Prem Prakash Kushwaha Shiv Verma Shashank Kumar Sanjay Gupta 
Androgen deprivation therapy(ADT)is the standard of care treatment for advance stage prostate cancer.Treatment with ADT develops resistance in multiple ways leading to the development of castration-resistant prostate ...
关键词:Prostate cancer second-generation antiandrogens cancer stem cells castration resistance prostate cancer androgen deprivation therapy 
Androgen receptor: structure, role in prostate cancer and drug discovery被引量:44
《Acta Pharmacologica Sinica》2015年第1期3-23,共21页MH Eileen TAN Jun LI H Eric XU Karsten MELCHER Eu-leong YONG 
Androgens and androgen receptors (AR) play a pivotal role in expression of the male phenotype. Several diseases, such as androgen insensitivity syndrome (AIS) and prostate cancer, are associated with alterations i...
关键词:ANDROGEN ANDROGEN RECEPTOR PROSTATE cancer nuclear RECEPTOR DRUG discovery rational DRUG design structural biology CASTRATION resistance ANTIANDROGEN 
Novel flutamide regulated genes in the rat veritral prostate: differential modulation of their expression by castration and flutamide treatments
《Asian Journal of Andrology》2007年第6期801-808,共8页Anil M Limaye Irfan Asangani Namrata Bora Paturu Kondaiah 
Aim: To identify flutamide regulated genes in the rat ventral prostate. Methods: Total RNA from ventral prostates of control and flutamide treated rats were isolated. Differentially expressed transcripts were identi...
关键词:ANDROGENS ANTIANDROGEN CASTRATION differential display reverse transcriptase polymerase chain reaction FLUTAMIDE PROSTATE 
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