MICS

作品数：348被引量：627H指数：11
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相关作者：郭刚王惠明周铁丽周丽萍王赛芳更多>>
相关机构：第三军医大学郑州大学上海中医药大学天津医科大学更多>>
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Transcriptome and proteome analysis reveals the characteristics of carbon metabolism in the mycelial development of Gomphus purpuraceus
《Food Science and Human Wellness》2025年第3期941-957,共17页Yangyang Geng Shixin Zhang Yana Liu Likang Qin 
the Science and Technology Program of Guizhou Province(2022-General 112);the Major Scientific and Technological Special Project of Guizhou Province(20193006-2);the Regional Fund Project of National Natural Science Foundation of China(32460795)。
Gomphus purpuraceus is an ancient wild edible mushroom.However,the niche and lignocellulose degradation system of G.purpuraceus have remained cryptic.In the current study,transcriptome and proteome sequencing of G.pur...
关键词：Gomphus purpuraceus Multi-omics CAZymes Lignocellulose decomposition FUMONISINS 
Integrated multi-omics characterization of neuroblastoma with bone or bone marrow metastasis
《Genes & Diseases》2025年第3期382-396,共15页Kai Huang Linyu Yang Yue Ma Lijian Cao Suwen Li Zhenzhen Zhao Jianwu Zhou Shan Wang 
supported in part by research grants from the Key Project of the National Key R&D Plan“Research on Prevention and Control of Major Chronic Non-Communicable Diseases”(China);the Ministry of Science and Technology of the People’s Republic of China,and the National Key R&D Program of China(No.2018YFC1313000,2018YFC1313004).
The pathogenesis of neuroblastoma with bone or bone marrow metastasis (NB-BBM)and its complex immune microenvironment remain poorly elucidated, hampering the advancement of effective risk prediction for BBM and limiti...
关键词：Bone marrow metastasis Bone metastasis IMMUNOTHERAPY Multi-omics NEUROBLASTOMA Transketolase(TKT) 
Multi-omics analysis reveals the epitranscriptomic and proteomic regulation network of tomato in low-temperature stress response
《Horticultural Plant Journal》2025年第2期758-773,共16页Na Wang Yanting Li Tianli Guo Libo Jiang 
financially supported by the National Natural Science Foundation of China(Grant Nos.32202518 and 32070601);Shandong University of Technology PhD Start-up Fund(418097)。
Tomato(Solanum lycopersicum)is an extensively cultivated vegetable,and its growth and fruit quality can be significantly impaired by low temperatures.The widespread presence of N^(6)-methyladenosine(m^(6)A)modificatio...
关键词：Epitranscriptome m^(6)A methylation PROTEOME Alternative polyadenylation Low temperature TOMATO 
Multi-omics reveals the associations among the fecal metabolome,intestinal bacteria,and serum indicators in patients with hepatocellular carcinoma
《World Journal of Gastroenterology》2025年第15期109-130,共22页Jing Feng Jun-Ping Wang Jian-Ran Hu Ping Li Pin Lv Hu-Cheng He Xiao-Wei Cheng Zheng Cao Jia-Jing Han Qiang Wang Qian Su Li-Xin Liu 
Supported by the Department of Science and Technology of Shanxi Province,No.20210302124369;the Health Commission of Shanxi Province,No.2021116;Shanxi Administration of Traditional Chinese Medicine,No.2024ZYY2C054.
BACKGROUND Hepatocellular carcinoma(HCC),the predominant form of primary liver cancer,is a key contributor to cancer-related deaths globally.However,HCC diagnosis solely based on blood biochemical markers lacks both s...
关键词：Hepatocellular carcinoma Fecal metabolomics Intestinal bacteria Correlation analysis Non-targeted liquid chromatography-mass spectrometry 
Karnofsky功能状态与血液透析患者营养不良-炎症综合征(MICS)发生及严重程度的相关性研究
《中文科技期刊数据库(全文版)医药卫生》2025年第3期032-035,共4页焦冬雪 魏丽 
探讨Karnofsky功能状态与血液透析患者营养不良-炎症综合征(MICS)发生及严重程度的相关性。方法 方便取样选取2023年9月—2024年8月入院100例血液透析患者为研究对象,根据其Karnofsky功能状态分为独立组、半独立组和非独立组,评估患者M...
关键词：Karnofsky功能状态 血液透析 营养不良-炎症综合征 严重程度 
Traditional Chinese medicine phenomics research on glycolipid metabolism disorder:a review
《Digital Chinese Medicine》2025年第1期49-58,共10页Xinyi FANG Linxuan MIAO Yanjiao ZHANG Yuxin ZHANG Runyu MIAO Huifang GUAN Jiaxing TIAN 
National Natural Science Foundation of China(82474323);High Level Chinese Medical Hospital Promotion Project(HLCMHPP20230CZ40907);China Academy of Chinese Medical Sciences Outstanding Young Scientific and Technological Talents Program(ZZ13-YQ-026).
Traditional Chinese medicine(TCM)has demonstrated unique advantages in the prevention and treatment of chronic diseases such as glycolipid metabolism disorder.However,its widespread application has been hindered by th...
关键词：Traditional Chinese medicine(TCM) PHENOMICS Multi-omics Glycolipid metabolism disorder Syndrome 
Plant metabolomics:applications and challenges in the era of multi-omics big data
《aBIOTECH》2025年第1期116-132,共17页Yingchen Hao Zhonghui Zhang Enxi Luo Jun Yang Shouchuang Wang 
financially supported by grants from the National Natural Science Foundation of China(No.32101662);Natural Science Foundation of Hainan Province(No.323RC421);Hainan Province Science and Technology Special Fund(No.ZDYF2022XDNY144);Hainan Provincial Academician Innovation Platform Project(No.HD-YSZX-202004);Hainan University Startup Fund(No.KYQD(ZR)21025);Collaborative Innovation Center of Nanfan and High-Efficiency Tropical Agriculture,Hainan University(No.XTCX2022NYB06).
Plant metabolites are crucial for the growth,development,environmental adaptation,and nutritional quality of plants.Plant metabolomics,a key branch of systems biology,involves the comprehensive analysis and interpreta...
关键词：Metabolomics Mass spectrometry Multi-omics Metabolic pathways Metabolic regulation 
Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors
《Acta Pharmacologica Sinica》2025年第3期702-714,共13页Lin-hui Zhai Xing-long Jia Yu-lu Chen Mu-yin Liu Jing-dan Zhang Shao-jie Ma Xiu-jun Wang Wen-hao Cheng Jing-liang He Jiao-jiao Zhou Ling-yi Zuo Mei-qi Zhang Qing Yuan Meng-han Xu Jing Ji Min-jia Tan Bin Liu 
supported by grants from the National Natural Science Foundation of China(82273167,22225702,32171434);the Program of Shanghai Academic Research Leader(22XD1420900);the State Key Laboratory of Drug Research(SIMM2105KF-13);Jiangsu Province Basic Research Program Natural Science Foundation(Outstanding Youth Fund Project,BK20220063);the Key Program of Basic Science(Natural Science)of Jiangsu Province(22KJA350001);“Huaguo Mountain Talent Plan”of Lianyungang City(Innovative Talents to Bin Liu).
Colchicine is a widely prescribed anti-inflammatory drug for the treatment of gout,familial Mediterranean fever and pericarditis,but its narrow therapeutic window presents a significant risk of severe toxicity.Despite...
关键词：COLCHICINE MLN4924 multi-omics analysis PHOSPHOPROTEOMICS ubiquitinomics kinase inhibitor 
Multi-omics analysis reveals a novel NFE2L3 variant impairing choroidal vasculature development in high myopia and myopic maculopathy
《National Science Review》2025年第2期5-8,共4页Jiangnan He Luyao Ye Hannan Xu Huanjie Yang Juan Shen Menghan Li Shijun Weng Dongyue Jiao Chen Chu Qijun Liao Haidong Zou Jianfeng Zhu Chenji Wang Xun Xu 
supported by the National Key Research and Development Program of China(2022YFC2502800,2019YFC0840607,2022YFA1104200 and 2022YFC2703102);Na-tional Natural Science Foundation of China(82171100,92357301,32370726,82304089 and 82401301);Natural Science Foundation of Shang-hai(23ZR1459200 and 22ZR1406600);Shanghai Key Disciplines to strengthen the construction of Public health system Three-year action Plan(2023-2025)(GWVI-11.1-22);Shanghai Shenkang Hospi-tal Clinical Research Program(SHDC12020127);Science and Technology Research Program of Shanghai(9DZ2282100);China Postdoctoral Science Foundation(2024M752442)。
Myopic maculopathy(MM)is a severe complication of high myopia,character-ized by degenerative lesions in the mac-ular retina,choroid and sclera[1].The pooled prevalence of MM is estimated to be 2.1%in the world populat...
关键词：MYOPIA MACULOPATHY prognosis 
Harnessing multi-omics approaches to elucidate the role of Chinese herbal compounds in chemotherapy-induced gastrointestinal damage
《World Journal of Gastrointestinal Oncology》2025年第2期35-40,共6页Chang Qiao Hao-Xiang Zhang Xiao-Tong Tian Yan-Jing Zhang De-Hui Li 
Supported by 2023 Government-funded Project of the Outstanding Talents Training Program in Clinical Medicine,No.ZF2023165;Key Research and Development Projects of Hebei Province,No.18277731D;Natural Science Foundation of Hebei Province,No.H202423105.
In this editorial,we discuss the findings reported by Wang et al in the latest issue of the World Journal of Gastrointestinal Oncology.Various research methodologies,including microbiome analysis,assert that the Tzu-C...
关键词：Chinese herbal compounds Gastrointestinal microenvironment CHEMOTHERAPY Multi-omics Intestinal microecology 
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