ACRYL

作品数：32被引量：28H指数：3
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相关领域：医药卫生理学更多>>
相关作者：何惠明王忠义谢超沈丽娟韩颖更多>>
相关机构：第四军医大学中南财经政法大学上海交通大学医学院附属第九人民医院齐齐哈尔大学更多>>
相关期刊：《Journal of Biomedical Research》《Neural Regeneration Research》《Food and Nutrition Sciences》《牙体牙髓牙周病学杂志》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Procyanidin A_1 and its digestive products alleviate acrylamide-induced IPEC-J2 cell damage through regulating Keap1/Nrf2 pathway
《Food Science and Human Wellness》2024年第3期1475-1484,共10页Fangfang Yan Qun Lu Chengming Wang Rui Liu 
supported by the project from National Natural Science Foundation of China (31671962);Fundamental Research Funds for the Central Universities (2662019PY034)。
Our previous study has revealed that procyanidin A_(1)(A_(1))and its simulated digestive product(D-A,)can alleviate acrylamide(ACR)-induced intestine cell damage.However,the underlying mechanism remains unknown.In thi...
关键词：Procyanidin A_1 Digestive products Acrylamide Nuclear factor erythroid 2-related factor 2(Nrf2) Intestinal cell damage 
Preparation and properties of poly(ethylene glycol)-bpoly( 3-acrylamidophenylboronic acid) glucose responsive particles and their hyaluronic acid-based microneedle patches
《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》2024年第5期395-410,共16页Yichuan HONG Haojie YU Li WANG Xiang CHEN Di SHEN Yu WANG Shuning REN Yudi HUANG Jian YANG 
supported by the Natural Science Foundation of Zhejiang Province(No.LHDMZ22H300003);the Science and Technology Program of Zhejiang Province(No.2019C03063),China。
To overcome the pain and risk of hypoglycemia in insulin administration,glucose-responsive microneedles have been developed by researchers,which could release insulin according to the blood glucose level.We designed a...
关键词：Diabetes Hyaluronic acid Phenylboronic acid(PBA) Glucose responsive hydrogel MICRONEEDLES 
Protective mechanism of quercetin compounds against acrylamide-induced hepatotoxicity
《Food Science and Human Wellness》2024年第1期225-240,共16页Linzi Li Xueying Lei Lin Chen Ya Ma Jun Luo Xuebo Liu Xinglian Xu Guanghong Zhou Xianchao Feng 
supported by the National Natural Science Foundation of China(32072142,31972099);Guangxi Science and Technology Base and Talent Special Projects(Guike AD21220004)。
Quercetin compounds have antioxidant,anti-inflammatory and anticancer pharmacological functions.Longterm exposure to acrylamide(AA)can cause liver injury and endanger human health.However,whether quercetin compounds c...
关键词：Quercetin compounds ACRYLAMIDE Protection mechanism Oxidative stress Antioxidant activity 
Addition of ‘Chetoui’ olive leaf extract to reduce acrylamide in Californian-style black olive
《Food Bioscience》2022年第6期842-851,共10页Dalel Mechi Antonio Fernández Bechir Baccouri Leila Abaza Daniel Martín-Vertedor 
financial support from the Junta de Extremadura(project IB21121);which is co-funded by the European Regional Development Fund;Furthermore,this work has been supported by Junta de Extremadura with the following projects:i)GR21121,and ii)“Garantía Juvenil”contract(TE-0078-19).
To improve food quality, the use of olive leaf extracts has been an emergent strategy that needs to be study in different scenarios. Certain local olive varieties are waiting to be discovered as potential by-product s...
关键词：Tunisia Olive leaf extract ACRYLAMIDE Phenolic compounds Table olive 
Exposure to Acrylamide in the Sixth Total Diet Study-China,2016-2019被引量：1
《China CDC weekly》2022年第9期161-164,共4页Feng Zhu Yuxin Wang Hualiang Liu Bing Lyu Dawei Chen Jingguang Li Wenliang Ji Yunfeng Zhao Yongning Wu 
Supported by the National Key Research and Development Program of China(NO.2017YFC 1600500);CAMS Innovation Fund for Medical Science(CIFMS 2019-I2M-5-024).
Summary What is already known about this topic?Acrylamide(AA)is toxic and potentially carcinogenic and could be formed during the cooking process.It is understood that almost all foods cooked at high temperature conta...
关键词：COOKING stuff TOTAL 
Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoid arthritis
《Acta Pharmaceutica Sinica B》2021年第3期795-809,共15页Fanxun Zeng Shiliang Li Guantian Yang Yating Luo Tiantian Qi Yingfan Liang Tingyuan Yang Letian Zhang Rui Wang Lili Zhu Honglin Li Xiaoyong Xu 
supported by the National Key Research and Development Program (2017YFD0200505 to Xiaoyong Xu,2016YFA0502304 to Honglin Li, China);the National Natural Science Foundation of China (81825020 to Honglin Li, 81803437to Shiliang Li);the National Science&Technology Major Project“Key New Drug Creation and Manufacturing Program”(2018ZX09711002, China);the Fundamental Research Funds for the Central Universities;the Shanghai Foundation of Science and Technology (15431902100 to Xiaoyong Xu);sponsored by Shanghai Sailing Program (No. 18YF1405100,China);sponsored by the National Program for Special Supports of Eminent Professionals;National Program for Support of Top-Notch Young Professionals,China。
Human dihydroorotate dehydrogenase(DHODH) is a viable target for the development of therapeutics to treat cancer and immunological diseases, such as rheumatoid arthritis(RA), psoriasis and multiple sclerosis(MS). Here...
关键词：DHODH De novo pyrimidine biosynthesis DHODH inhibitors Acrylamide derivatives Rheumatoid arthritis 
Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway被引量：5
《Neural Regeneration Research》2021年第1期150-157,共8页Xiao Chen Jing-Wei Xiao Peng Cao Yi Zhang Wen-Jian Cai Jia-Yang Song Wei-Min Gao Bin Li 
This study was supported by the National Natural Science Foundation of China,Nos.81773474 and 81273110(to BL);the National Key Research and Development Project of China,No.2017YFF0211201(to BL).
Acrylamide has been shown to be neurotoxic.Brain-derived neurotrophic factor(BDNF)can alleviate acrylamide-induced synaptic injury;however,the underlying mechanism remains unclear.In this study,dibutyryl-cyclic adenos...
关键词：factor INJURY pathway peripheral nerve protection protein regeneration repair 
The protective effects of Gastrodia elata Bl.decoction and Gastrodin on Acrylamide-induced DNA damage in mice
《Asian Journal of Traditional Medicines》2020年第6期299-308,共10页Fan Wang Kuo Zhang Xiaoya Du Jingyu Yang Chunfu Wu 
Acrylamide(AA)is ubiquitous in packaging materials,paints,cosmetics,food and drinking water.However,AA has obvious neurotoxicity,reproductive toxicity and carcinogenicity,which seriously endangers human health.As one ...
关键词：DNA damage Gastrodia elata Bl.decoction GASTRODIN acrylamide oxidative stress 
Method Development and Validation for the Quantification of Acrylamide in Potato Chips and Other Locally Available Food by LC-MS/MS in Bangladesh
《Food and Nutrition Sciences》2019年第7期876-892,共17页Mala Khan Md. Moniruzzaman Mamudul Hasan Razu 
A sensitive, precise, accurate and simple in house validated Liquid Chromatography and Tandem mass spectrometric (LC-MS/MS) analytical method was developed for the quantification of acrylamide in potato chips, a proba...
关键词：LC-MS/MS ACRYLAMIDE LINEARITY Accuracy Precision LOD LOQ 
Acrylamide induces HepG2 cell proliferation through upregulation of miR-21 expression
《The Journal of Biomedical Research》2019年第3期181-191,共11页Yuyu Xu Pengqi Wang Chaoqi Xu Xiaoyun Shan Qing Feng 
supported by the National Natural Science Foundation of China (81472977); foundation from the Priority Academic Program Development of Jiangsu Higher Education Institutions; Graduate Student Practice and Innovation Project of Jiangsu Province Ordinary University (SJZZ15_0117)
Acrylamide, a potential carcinogen, exists in carbohydrate-rich foods cooked at a high temperature. It has been reported that acrylamide can cause DNA damage and cytotoxicity. The present study aimed to investigate th...
关键词：ACRYLAMIDE PROLIFERATION MIR-21 
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