GASTRODIN

作品数：38被引量：211H指数：10
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相关领域：医药卫生更多>>
相关作者：戴均贵郭洪祝果德安朱丹萌巩卓更多>>
相关机构：北京大学华东理工大学更多>>
相关期刊：《外文科技期刊数据库（文摘版）医药卫生》《Neural Regeneration Research》《Journal of Hainan Medical University》《Bioactive Materials》更多>>
相关基金：国家自然科学基金教育部跨世纪优秀人才培养计划国家杰出青年科学基金更多>>
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Exploring the Mechanism of Action of Gastrodin in Parkinson's Disease Based on Network Pharmacology
《Medicinal Plant》2024年第4期16-19,25,共5页Feifan LIU Shifang LUO Yan WAN Linao ZHANG Xue WU Yuhuan XIE Peixin GUO 
National Natural Science Foundation of China(81660671);Science and Technology Plan Project of Science and Technology Department of Yunnan Province(202101AZ070001-172);Key Laboratory of Formulation Granules of Yunnan Province(202105AG070014);National Administration of Traditional Chinese Medicine High-level Key Discipline Construction Project‘Dai Pharmacy’(zyyzdxk-2023192).
[Objectives]To explore the mechanism of action of gastrodin in the treatment of Parkinson's disease(PD)by employing network pharmacology technology,and to provide a scientific theoretical basis for the rational clinic...
关键词：Parkinson's disease Network pharmacology GASTRODIN 
A biomimetic tri-phasic scaffold with spatiotemporal patterns of gastrodin to regulate hierarchical tissue-based vascular regeneration
《Bioactive Materials》2024年第8期512-527,共16页Yingrui Hu Limei Li Qing Li Shilin Pan Guangli Feng Xiaoqian Lan Jianlin Jiao Lianmei Zhong Lin Sun 
funded by National Natural Science Foundation of China(grant no.82260088,81960251,82260366);Yunnan Provincial Innovative Research Team in Basic and Clinical Study of Coronary Heart Disease of Yunnan Revitalization Talent Support Program(202305AS350030);Yunnan Science and Technology Program(202401AY070001-030,202201AT070136,202301AY070001-032,202001AY070001-014);Bai Xiaochun expert workstation(YSZJGZZ-2020040);Major Program of Kunming Science and Technology Innovation Center(2019-1-N-25318000003568).
Clinical use of small-diameter vascular grafts remains a challenging issue in neovessel regeneration in view of thrombosis and intimal hyperplasia.Developing a vascular graft with structure and function similar to tho...
关键词：Tri-phasic structure Hierarchical release of gastrodin ANTI-COAGULATION Intimal hyperplasia REGENERATION 
Pharmacological effects and mechanisms of Gastrodia elata and its active ingredients in the treatment of cardiovascular diseases被引量：3
《Traditional Medicine Research》2023年第9期34-48,共15页Xing-Yi Chen Yan He Ji-Yu Chen 
This study was funded by the National Natural Science Foundation of China(82260096);the Science and Technology Foundation of Basic Research Program of Guizhou Province([2023]General 371,[2020]1Y381);the Science and Technology Foundation of Health Commission of Guizhou Province(2022XMSB00037954).
Gastrodia elata,a traditional Chinese medicine belonging to the Orchidaceae family,contains several major components such as gastrodin,polysaccharides of Gastrodia elata,and parishin.The pharmacological studies conduc...
关键词：Gastrodia elata GASTRODIN parishin polysaccharides of Gastrodia elata Gastrodia elata extracts cardiovascular diseases 
Gastrodin ameliorates exercise-induced fatigue via modulating Nrf2 pathway and inhibiting inflammation in mice被引量：4
《Food Bioscience》2023年第1期745-761,共17页Yaping Zhou Qi Wu Wen Yu Fan Ye Yunyun Cao Otobong DAkan Xiuxiu Wu Tiantian Xie Han Lu Fuliang Cao Feijun Luo Qinlu Lin 
supported by Program for Science&Technology Innovation Platform of Hunan Province(2019TP102);Graduate Innovative Research Project of Hunan province and Central South University of Forestry and Technology(CX20210862,CX202101027);Science and Technology Plan Project of Changsha City(kq2014275).
Gastrodia elata Bl.is traditional Chinese medicine used to alleviate fatigue,but its underlying mechanism is still unclear.This study explored the anti-fatigue mechanism of gastrodin by exercise-induced fatigue model ...
关键词：ANTI-FATIGUE GASTRODIN Network pharmacology Molecular mechanism Nrf2 signaling pathway 
Sequential gastrodin release PU/n-HA composite scaffolds reprogram macrophages for improved osteogenesis and angiogenesis被引量：6
《Bioactive Materials》2023年第1期24-37,共14页Limei Li Qing Li Li Gui Yi Deng Lu Wang Jianlin Jiao Yingrui Hu Xiaoqian Lan Jianhong Hou Yao Li Di Lu 
supported by the National Natural Science Foundation of China(82160175/81860326);Department of Science and Technology of Yunnan Province of China(2017FF117(-062)/202101AY070001-078);100 Talents Program of Kunming Medical University(Limei Li).
Wound healing is a highly orchestrated process involving a variety of cells,including immune cells.Developing immunomodulatory biomaterials for regenerative engineering applications,such as bone regeneration,is an app...
关键词：Gastrodin-delivery Immune/inflammatory response OSTEOGENESIS ANGIOGENESIS Tissue repair 
Clinical Value Analysis of Alprazolam Combined with Gastrodin in the Treatment of Neurasthenia
《外文科技期刊数据库(文摘版)医药卫生》2022年第6期060-063,共4页LIYanan 
Objective: to explore the clinical effect of alprazolam combined with gastrodin on neurasthenia patients, and to improve their mental state and sleep quality. Methods: 100 patients with neurasthenia admitted to our ho...
关键词：NEURASTHENIA ALPRAZOLAM GASTRODIN mental state sleep quality 
Cardiovascular protective properties of gastrodin被引量：2
《Asian Pacific Journal of Tropical Biomedicine》2022年第4期141-147,共7页Shu-Ting Yang Shu-Bai Liu 
Cardiovascular diseases cause significant morbidity and mortality worldwide,incurring a major public health burden.Gastrodia elata Blume is a traditional Chinese herbal medicine that has been widely used to treat cent...
关键词：GASTRODIN Cardiovascular diseases Myocardial ischemia-reperfusion injury Gastrodia elata Blume ANTI-ATHEROSCLEROSIS Cardio-protection 
Gastrodin modified polyurethane conduit promotes nerve repair via optimizing Schwann cells function被引量：6
《Bioactive Materials》2022年第2期355-367,共13页Hongcai Yang Qing Li Limei Li Shaochun Chen Yu Zhao Yingrui Hu Lu wang Xiaoqian Lan Lianmei Zhong Di Lu 
supported by the National Natural Science Foundation of China(81960251/81460210/81860326);the Department of Science and Technology of Yunnan Province of China(2019ZF011-2/2017FF117(-062)/2018IA048/2018FE001(-029)/2018FE001(-024));Scientific Research Fund of Yunnan Provincial Education Commission(2021J0229);the 100 Talents Program of Kunming Medical University(Limei Li).
Peripheral nerve regeneration and functional recovery remain a major clinical challenge.Nerve guidance conduit(NGC)that can regulate biological behavior of Schwann cells(SCs)and facilitate axonal regeneration through ...
关键词：Gastrodin/PU SCs biological behavior ANTI-INFLAMMATORY Peripheral nerve regeneration 
Effect Analysis of Gastrodin Combined with Betastine Hydrochloride in the Treatment of Dizziness
《外文科技期刊数据库(文摘版)医药卫生》2021年第12期780-782,共5页WANG Haiyang GAO Yufeng CHEN Dongli 
Objective: to analyze the clinical effect of gastrodin combined with betastine hydrochloride in patients with dizziness. Methods: 82 patients with dizziness in our hospital were analyzed from February 2020 to February...
关键词：GASTRODIN betastine hydrochloride DIZZINESS the effect 
Determination of the Content of Gastrodin in Jingtianshenma Tablets by High Performance Liquid Chromatography
《Medicinal Plant》2021年第6期15-16,19,共3页Kun TANG Hongzhen GUO Jie QIAO Bing LI 
School-level Scientific Research Fund of Langfang Normal University-Doctoral Research Startup Project(XBQ202032);Self Raised Project of Langfang Science and Technology Bureau(2019012001);the Project of Langfang Key Laboratory of Food Nutrition and Safety.
[Objectives]The research aimed to establish a high performance liquid chromatography method for the content determination of gastrodin in Jingtianshenma Tablets.[Methods]A phenomenex Luna C18(250 mm×4.6 mm,5μm)colum...
关键词：Jingtianshenma Tablets GASTRODIN HPLC Content determination 
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