financially supported by the National Natural Science Foundation of China(32072176,31271814);the Outstanding Youth Funds of Anhui Province(2208085J31);the Fundamental Research Funds for the Central Universities(JZ2022HGQA0232,JZ2022HGTA0316)。
In the present study,we investigated the intervention effects of a purified Polygonatum cyrtonema polysaccharide(PCP)on high-fat diet(HFD)-induced atherosclerosis in male and female LDLr-/-mice.Results showed that HFD...
the National Natural Science Foundation of China:Explore the Regulatory Mechanism of Coronary Endothelial Immune Inflammation Mediated by Micro RNA155-SOCS1 Axis in Bama Pigs based on “Xin Shou Qi Yu Pi”(No.81703970);the National 973 Program on Key Basic Research Project:Study on the Therapeutic Mechanism and Rule of Treating Angina Pectoris based on “Cong Pi Lun Zhi”(No.2013CB531704)
OBJECTIVE:To investiage the possible mechanism underlying the effect of the Jianpi Qutan Fang(健脾祛痰方,JPQT)on Atherosclerosis(AS)which is the main pathological process of most cardiovascular diseases that affect mi...
supported by the National Natural Science Foundation of China(Grant Nos:.82070356 and 81770337);the Key Project of Hunan Provincial Science and Technology Innovation,China(Grant No.:2020SK1013);the Hunan Provincial Natural Science Foundation of China(Grant No.:2021JJ30033).
Catalpol,an iridoid glucoside isolated from Rehmannia glutinosa,has gained attention due to its potential use in treating cardio-cerebrovascular diseases(CVDs).This extensive review delves into recent studies on catal...
Supported by the National Natural Science Foundation of China(No.81874432 and No.82074369);Science and Technology Planning Project of Guangdong Province(No.2018B030322012)。
Lectin-like oxidized low-density lipoprotein receptor-1(LOX-1)have recently been identified to be closely related to the occurrence and development of atherosclerosis(AS).A growing body of evidence has suggested Chine...
supported by the National Natural Science Foundation of China(Nos.81872823,82073782,81970374);the Shanghai Science and Technology Committee(No.19430741500)。
Plaque plays a central role in atherosclerosis(AS)progression,whereas inflammation and destruction of the plaque microenvironment contribute to plaque advancement.As a result,a therapy regime,which combines anti-infla...
Cardiovascular diseases cause significant morbidity and mortality worldwide,incurring a major public health burden.Gastrodia elata Blume is a traditional Chinese herbal medicine that has been widely used to treat cent...
This work was supported by the National Natural Science Foundation of China(31971301,31971242,12032007);the China Postdoctoral Science Foundation(2020M673143);the Natural Science Foundation of Chongqing(cstc2020jcyj-bsh0025,cstc2019jcyj-zdxmX0028,cstc2017jcyjAX0186);Fundamental Research Funds for Central Universities(2020CDJQY-A061,2020CDJYGSX006,2019CDYGZD008,2018CDHB1B08)as well as the National‘111 Project’Base(B0625)are gratefully acknowledged.
The development of nanomedicines provides new opportunities for the treatment of atherosclerosis(AS)due to their great advantages such as the improved drug solubility,enhanced bioavailability and reduced side effects....
Supported by the National Natural Science Foundation of China(No.81173385)
Objective: To observe the effects of Xiongshao Capsule(芎芍胶囊, XSC) on anti-inflammatory properties of high-density lipoprotein(HDL), myeloperoxidase(MPO) and paraoxonase 1(PON1) in serum of atherosclerosis...
Coptis Chinensis is a traditional Chinese medicine herb that has the effect of clearing heat and drying dampness,purging fire to eliminate toxin.Berberine is the main alkaloid of Coptis Chinensis,and recent researches...
The effects of Rhubarb and Salvia Miltiorrhiza on serum lipids, aortic cholestercl contentand liver LDL receptor mRNA level in experimental rats were observed. The result showed that:(1)Rhuberb significantly decreased...