BETA-CELLS

作品数:7被引量:105H指数:2
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相关领域:医药卫生生物学更多>>
相关期刊:《Modeling and Numerical Simulation of Material Science》《Chinese Medical Sciences Journal》《Asian Pacific Journal of Tropical Biomedicine》《World Journal of Gastroenterology》更多>>
相关基金:国家自然科学基金更多>>
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Mathematical Model for the Dynamics of Glucose, Insulin and β-Cell Mass under the Effect of Trauma, Excitement and Stress
《Modeling and Numerical Simulation of Material Science》2019年第4期71-96,共26页Isa Ibrahim Mohammed Ibrahim Isa Adamu Seni James Barka 
In this work, we presented a mathematical model for the dynamics of glucose, insulin and beta-cell mass under the influence of trauma, excitement and/or stress, the model is an improvement on the work by?[1]. We defin...
关键词:Mathematical Model EPINEPHRINE Prolong HYPERGLYCEMIA NORMOGLYCEMIA BETA-CELLS Diabetic with COMPLICATION Equilibrium and Stability 
Intra-islet endothelial cell and β-cell crosstalk: Implication for islet cell transplantation被引量:1
《World Journal of Transplantation》2017年第2期117-128,共12页Siddharth Narayanan Gopalakrishnan Loganathan Maheswaran Dhanasekaran William Tucker Ankit Patel Venugopal Subhashree SriPrakash Mokshagundam Michael G Hughes Stuart K Williams Appakalai N Balamurugan 
The intra-islet microvasculature is a critical interface between the blood and islet endocrine cells governing a number of cellular and pathophysiological processes associated with the pancreatic tissue. A growing bod...
关键词:ISLETS Endothelial cells ISLET cell transplantation BETA-CELLS MICROVASCULATURE PARACRINE signalling 
Alterations of the Ca2+ signaling pathway in pancreatic beta-cells isolated from db/db mice被引量:2
《Protein & Cell》2014年第10期783-794,共12页Kuo Liang Wen Du Jingze Lu Fei Li Lu Yang Yanhong Xue Bertil Hille Liangyi Chen 
Upon glucose elevation, pancreatic beta-cells secrete insulin in a Ca2+-dependent manner. In diabetic animal models, different aspects of the calcium signaling path- way in beta-cells are altered, but there is no con...
关键词:diabetic beta-cells calcium signalingalterations SERCA pump db/db mice 
Adipose stem cell-based regenerative medicine for reversal of diabetic hyperglycemia被引量:5
《World Journal of Diabetes》2014年第3期235-243,共9页Hyun Joon Paek Courtney Kim Stuart K Williams 
Diabetes mellitus(diabetes) is a devastating disease that affects millions of people globally and causes a myriad of complications that lead to both patient morbidity and mortality. Currently available therapies, incl...
关键词:DIABETES MELLITUS DIABETES Insulin Stem cells ADIPOSE PANCREAS BETA-CELLS Differentiation 
Histological changes and antidiabetic activities of Icacina trichantha tuber extract in beta-cells of alloxan induced diabetic rats被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2013年第8期628-633,共6页Onakpa Michael Monday Asuzu Isaac Uzoma 
Financially supported by the Institute of International Education (IIE)of the United States Department of State’s Bureau for Educational and Cultural Affairs(Grant No.15120356)
Objective:To investigate the antidiabetic,hypolipidaemic activities and histopathological changes ofIcacina trichantha(I.trichantha)tuber extract in alloxan induced diabetic rats.Methods:In the present study,80%methan...
关键词:Icacina trichantha Diabetes mellitus GLIBENCLAMIDE ALLOXAN MONOHYDRATE Rats 
Linoleic Acid Activates GPR40/FFA1 and Phospholipase C to Increase [Ca^(2+)]_i Release and Insulin Secretion in Islet Beta-Cells被引量:2
《Chinese Medical Sciences Journal》2012年第1期18-23,共6页Yi-jun Zhou Yu-ling Song Hui Zhou Yan Li 
Supported by Grant from Department of Education of Liaoning Province (2008810)
Objective To elucidate GPR40/FFA1 and its downstream signaling pathways in regulating insulin secretion. Methods GPR40/FFA1 expression was detected by immunofluorescence imaging. We employed linoleic acid (LA), a free...
关键词:GPR40 / FFA 1 phospholipase C antisense oligonucleotides intracellular calcium linoleic acid 
Differentiation of rat marrow mesenchymal stem cells into pancreatic islet beta-cells被引量:94
《World Journal of Gastroenterology》2004年第20期3016-3020,共5页Li-BoChen Xiao-BingJiang LianYang 
Supported by the National Natural Science Foundation of China,No.30170911
AIM: To explore the possibility of marrow mesenchymal stem cells (MSC) in vitro differentiating into functional isletlike cells and to test the diabetes therapeutic potency of Islet-like cells. METHODS: Rat MSCs were ...
关键词:老鼠 骨髓间叶细胞 细胞系统 胰岛 Β细胞 免疫细胞化学 
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