Tsinghua Berkeley Shenzhen Institute and the Project of Basic Research of Shenzhen,China(JCYJ20170412101508433&JCYJ20180507183655307);National Key Research and Development Program of China(2023YFE0203100);National Natural Science Foundation of China(Grant Nos.82271051,82070926).
Fungal corneal ulcer is one of the leading causes of corneal blindness in developing countries.Corneal scars such as leukoplakia are formed due to inflammation,oxidative stress and non-directed repair,which seriously ...
The research were supported by Grant Nos.304688/2021-5 and21/2022.
Background Oral cancer is one of the most common types of cancer in men causing mortality if not diagnosedearly.In recent years,computer-aided diagnosis(CAD)using artificial intelligence techniques,in particular,deepn...
Vulvar leukoplakia refers to the chronic disease of degeneration and hypopigmentation of the skin and mucous membrane of the vulva with unbearable itching in women, seriously affecting the quality of life. The main tr...
Quality of life(QoL) is a vital and often required health outcome measure that is relevant to patient care. A healthy oral cavity enables person to perform daily activities without any limitations. However, any distur...
Nowadays, biomedicine development is caused by the necessity of fast premalignant and malignant diagnosis. In the case of cancer, it is important to identify degree of tumor’s malice. We investigated the differences ...
AIM To elucidate the profile of the salivary proteome.METHODS Unstimulated whole mouth saliva was collected from 30 volunteers [15 proliferative verrucous leukoplakia(PVL) patients and 15 controls] and proteins were s...
Proliferative verrucous leukoplakia is an intriguing disease, which occurs particularly in women aged greater than 60 years, is not associated with tobacco and alcohol, and has a high risk of recurrence and malignant ...
Precancerous lesions of oral mucosa, known as potentially malignant disorders in recent years, are consists of a group of diseases, which should be diagnosed in the early stage. Oral leukoplakia, oral submucous fibros...
supported by Education Department of Anhui(NoKJ2012Z148)
Objective:To study the relationship of the expressions of p53 and mdm2 in leukoplakia cancer.Methods:RT-PCR was used to detect the mRNA of p53,mdm2 in patients with leukoplakia cancer.The frequencies of p53,mdm2 in pe...