This work was supported by the Natural Science Foundation of Hubei Province(No.2019CFB753);the Hubei Technological Innovation Special Fund(No.2019ACA132);the Hubei Natural Science Foundation(No.2020CFB805).
Objective Paroxysmal kinesigenic dyskinesia(PKD)is a rare movement disorder PRRT2 gene mutations have been reported to cause PKD.However,the pathophysiological mechanism of PKD remains unclear,and it is unknown whethe...
The transcriptional factor GATA-6 gene produces two translational isoforms from a single mRNA through ribosomal leaky scanning. L-type GATA-6 has an extension of 146 amino acid residues at its amino terminus. In the e...
Supported by the National Key Technology Research and Development Program of China (2012BAK08B07);the National Natural Science Foundation of China (31201919)~~
[Objective] This study aimed to analyze the type III effector tccP and tccP2 genes in Escherichia coli O157:H7 from Chinese water-chestnut. [Method] Gene-specific and locus-specific primers were utilized to amplify t...
To complete their life cycle and spread, viruses interfere with and gain control of diverse cellular processes, this most often occurring through interaction between viral proteins(VPs) and resident protein partners. ...
supported by grants from the National Natural Science Foundation of China (30870785);the Natural Science Foundation of Guangdong Province, China (9351008901000003)
Objective Formation of the endophilin II-Ca 2+ channel complex is Ca 2+ -dependent in clathrin-mediated endocytosis. However, little is known about whether the other two endophilin isoforms have the same features. T...
Supported by the National Natural Science Foundation of China(30700822)
Proline-rich tyrosine kinase 2 (Pyk2) is a nonreceptor protein tyrosine kinase,which is also known as Ca2 +-dependent tyrosine kinase or related adhesion focal tyrosine kinase.Pyk2 activation exerts a critical regulat...
the National Natural Science Foundation of China (Grant No. 30570165);Natural Science Foundation of Guangdong Province of China (Grant Nos. 5005912 and 2006A20101007)
PRPs (proline-rich proteins) are a group of cell wall proteins characterized by their proline and hy- droproline-rich repetitive peptides. The expression of PRPs in plants is stimulated by wounding and environmental s...
Project supported in part by Anhui Key Laboratory of Eco-engineering and Biotechnique Fund and National Institutes of Health Grants GM60033-03
Aim: To study the expression of proline-rich Akt-substrate PRAS40 in the cell survival pathway and tumor progression. Methods: The effects of three key kinase inhibitors on PRAS40 activity in the cell survival pathw...
The distribution of salivary acidic proline-rich proteins pheno-types was investigated by using the ultra-thin PAGIEF technique in 258 ChineseHan populations in Liaoning area. The gene frequencies were as follows: Pr^...