BASAL-LIKE

作品数:10被引量:28H指数:3
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相关领域:医药卫生更多>>
相关作者:陈红风叶媚娜刘鹏熙廖明娟周瑞芳更多>>
相关机构:上海中医药大学安徽省阜阳市人民医院北京大学广东省中医院更多>>
相关期刊:《Science China(Life Sciences)》《Advances in Breast Cancer Research》《益寿宝典》《哈尔滨医科大学学报》更多>>
相关基金:北京市自然科学基金国家自然科学基金国家科技部专项基金国家重点基础研究发展计划更多>>
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A shifting adversary:control of pancreatic cancer transcriptomic subtypes
《Journal of Cancer Metastasis and Treatment》2022年第1期253-264,共12页Charles J.David 
Cellular plasticity,the dynamic ability of cells to adopt distinct transcriptional states,plays a well-known role in the pancreas during the initiation of pancreatic ductal adenocarcinoma(PDA),the most common form of ...
关键词:Pancreatic ductal adenocarcinoma transcriptional subtypes classical BASAL-LIKE squamous quasi-mesenchymal cellular plasticity transcription factors tumor microenvironment 
细胞分裂周期相关蛋白7通过增强细胞增殖和干性促进人乳腺癌进程被引量:2
《解剖学报》2020年第6期888-896,共9页杨得草 刘程 马集 王梦远 战军 张宏权 
国家自然科学基金(81230051,81472734,31170711,81321003,81773199,30830048);科技部专项基金(2016YFC1302103,2015CB553906);北京市自然科学基金(7120002)。
目的探讨细胞分裂周期相关蛋白7(CDCA7)在人类乳腺癌中的相关功能及潜在的作用机制。方法通过癌症和肿瘤基因图谱(TCGA)数据库分析检索出不同乳腺癌亚型差异表达基因,找到在基底型乳腺癌中高表达基因,在这些基因中找到CDCA7,通过临床患...
关键词:细胞分裂周期相关蛋白7 Basal-like/luminal乳腺癌 干细胞 Β-连环蛋白 流式细胞术  
乳腺癌单样本预测器可在RNA-seq数据中一致鉴定出Basal-like亚型乳腺癌
《益寿宝典》2020年第12期178-179,共2页李项南 蔡栋梁 金雨欣 
探究乳腺癌单样本预测器(singlesamplepredictor,SSP)在RNA-seq中鉴定Basal-like亚型乳腺癌的一致性与稳健性。方法:使用4种SSP联合3种数据校正方法,并按比例随机去掉一定比例的非Basal-like亚型样本。结果:不同的数据校正方法影响乳腺...
关键词:乳腺癌 预测器 鉴定 
DWI定量值对乳腺癌分子分型的鉴别诊断被引量:3
《中国中西医结合影像学杂志》2020年第1期36-39,共4页袁玉山 张杨 彭彬 张娜娜 胡献阔 
目的:探讨DWI对Her-2阳性过表达型乳腺癌和Basal-Like基底样型乳腺癌的鉴别诊断价值。方法 :收集经病理证实的74例乳腺癌,其中Her-2阳性过表达型43例,Basal-Like基底样31例,获取其DWI图像,后经GE AW 4.6工作站和Matlab软件分别获取病灶...
关键词:Her-2阳性过表达型乳腺癌 Basal-Like基底样乳腺癌 磁共振成像 弥散 直方图 LOGISTIC模型 
C1orf106, an innate immunity activator, is amplified in breast cancer and is required for basal-like/luminal progenitor fate decision被引量:2
《Science China(Life Sciences)》2019年第9期1229-1242,共14页Ji Ma Cheng Liu Decao Yang Jiagui Song Jing Zhang Tianzhuo Wang Mengyuan Wang Weizhi Xu Xueying Li Shigang Ding Jun Zhan Hongquan Zhang 
supported by the Ministry of Science and Technology of China (2016YFC1302103 and 2015CB553906);the National Natural Science Foundation of China (81230051, 81472734,31170711, 81321003, and 30830048);the Beijing Natural Science Foundation (7120002);the 111 Project of the Ministry of Education, Peking University (BMU2018JC004, BMU20120314, and BMU20130364);a Leading Academic Discipline Project of Beijing Education Bureau to H.Z;a grant from the National Natural Science Foundation of China (81773199) to J.Z
Basal-like breast cancer with a luminal progenitor gene expression profile is an aggressive subtype of breast cancer with a poorer prognosis compared with other subtypes.However,genes that specifically promote basal-l...
关键词:C1orf106 BASAL-LIKE LUMINAL PROGENITOR breast cancer ELF5 GATA3 
重构长非编码RNA介导的乳腺癌basal-like亚型相关药物互作网络
《哈尔滨医科大学学报》2019年第2期150-153,共4页苑振宽 刘力榕 海鑫 
目的基于长非编码RNA(lncRNA)及mRNA双重表达谱,构建乳腺癌basal-like亚型相关的lncRNA-mRNA-drug互作网络。方法以乳腺癌basal-like亚型为疾病模型,基于新一代测序技术构建乳腺癌长非编码RNA与编码RNA转录组分子图谱,采用关联有罪的原...
关键词:乳腺癌basal-like亚型 长非编码RNA 亚型相关药物互作网络 生物学功能 KEGG通路 
Cytotoxicity Study of Gold Nanoparticles on the Basal-Like Triple-Negative HCC-1937 Breast Cancer Cell Line
《Journal of Biomaterials and Nanobiotechnology》2018年第1期13-25,共13页Christophe Massard Clémence Dubois Vincent Raspal Pierre Daumar Yves Sibaud Emmanuelle Mounetou Mahchid Bamdad Oscar Komla Awitor 
The Triple Negative “Basal-like” breast cancer (TNBL) tumours have a high proliferative capacity and develop a resistance phenotype associated with metastases. However, the management of TNBL carcinomas is still not...
关键词:Breast Cancer “Basal-Like” Triple Negative HCC-1937 Gold Nanoparticles CYTOTOXICITY 
Cancer stem cells and early stage basal-like breast cancer被引量:3
《World Journal of Obstetrics and Gynecology》2016年第2期150-161,共12页Pang-Kuo Lo Benjamin Wolfson Qun Zhou 
Supported by The National Cancer Institute(NCI)of National Institutes of Health(NIH)of the United States of America to Zhou Q,Nos.5R01CA157779-03 and 5R01CA163820-04
Ductal carcinoma in situ (DCIS) is a category of early stage, non-invasive breast tumor defined by the intraductal proliferation of malignant breast epithelial cells. DCIS is a heterogeneous disease composed of mult...
关键词:Ductal carcinoma in situ Invasive ductal carcinoma Basal-like ductal carcinoma in situ Basal-like invasive ductal carcinoma Cancer stem cells 
Adenoid cystic carcinoma of breast: Recent advances被引量:18
《World Journal of Clinical Cases》2014年第12期732-741,共10页Kosuke Miyai Mary R Schwartz Mukul K Divatia Rose C Anton Yong Wook Park Alberto G Ayala Jae Y Ro 
Adenoid cystic carcinoma(ACC) of the breast is a rare special subtype of breast cancer characterized by the presence of a dual cell population of luminal and basaloid cells arranged in specific growth patterns. Most b...
关键词:ADENOID CYSTIC carcinoma BREAST Triplenegative and BASAL-LIKE PHENOTYPE HISTOLOGY Molecular genetic features 
Differential Expression of Glu-Tubulin in Basal-Like Phenotype Carcinoma of the Mammary Gland
《Advances in Breast Cancer Research》2013年第3期66-71,共6页Hajime Kuroda Yasuo Imai Kazuko Kuroso Masato Kojima Yoshihiko Ueda 
High levels of tubulin expression have been described in a variety of human malignant tumors, and glu-tubulin, in which the C-terminal tyrosine of α-tubulin is removed by tubulin carboxypeptidase. Over-expression has...
关键词:Glu-Tubulin BASAL-LIKE PHENOTYPE CARCINOMA MAMMARY Gland 
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