SULFOTRANSFERASE

作品数：16被引量：26H指数：2
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相关领域：医药卫生生物学更多>>
相关作者：李艳霞韦海澜冀希炜李健王思媛更多>>
相关机构：北京大学重庆医科大学汕头大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《生殖医学杂志》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金：国家自然科学基金教育部留学回国人员科研启动基金国家重点基础研究发展计划更多>>
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QM/MM Study on Enzymatic Mechanism in Sinigrin Biosynthesis被引量：1
《Chinese Journal of Chemical Physics》2022年第1期193-199,I0041-I0057,I0064,共25页Ya-Jie Guo Ya-Jun Liu 
supported by the National Natural Science Foundation of China(No.21973005)。
As the major and abundant type of glucosinolates(GL)in plants,sinigrin has potential functions in promoting health and insect defense.The final step in the biosynthesis of sinigrin core structure is highly representat...
关键词：SINIGRIN SULFOTRANSFERASE Molecular dynamics Quantum mechanics and molecular mechanics 
A sulfotransferase gene BnSOT-like1 has a minor genetic effect on seed glucosinolate content in Brassica napus被引量：1
《The Crop Journal》2020年第5期855-865,共11页Yangming Wang Shubei Wan Hao Fan Mao Yang Weiyan Li Rongzhan Guan 
This work was supported by the National Key Research and Development Program of China(2018YFD0100600);the National Natural Science Foundation of China(31270386);the Cyrus Tang Seed Innovation Center at Nanjing Agricultural University.
The theory and associated selection methods of classical quantitative genetics are based on the multifactorial or polygene hypothesis.Major genes or quantitative trait loci(QTL)in modern quantitative genetics based o...
关键词：Brassica napus Glucosinolate content Minor gene SULFOTRANSFERASE ICIM 
The interplay between hepatocyte nuclear factor 4α(HNF4α)and cholesterol sulfotransferase(SULT2B1b)in hepatic energy homeostasis被引量：1
《Liver Research》2019年第3期143-149,共7页Yuhan Bi Youya Wang Wen Xie 
supported in part by the USA National Institutes of Health(NIH)grants DK099232,ES023438 and ES030429 to W.Xie.W.Xie was supported in part by the Joseph Koslow Endowed Professorship from the University of Pittsburgh School of Pharmacy.
The nuclear receptor hepatocyte nuclear factor 4alpha(HNF4α)plays a critical role in the regulation of metabolic homeostasis,including glucose homeostasis.Sulfotransferases(SULTs)catalyze the transfer of a sulfate gr...
关键词：Nuclear receptor Hepatocyte nuclear factor 4alpha(HNF4a) Sulfotransferase(SULT) Cholesterol sulfotransferase 2B1b (SULT2B1b)Energy homeostasis 
Arenobufagin is a novel isoform-specific probe for sensing human sulfotransferase 2A1被引量：3
《Acta Pharmaceutica Sinica B》2018年第5期784-794,共11页Xiangge Tian Chao Wang Peipei Dong Yue An Xinyu Zhao Weiru Jiang Gang Wang Jie Hou Lei Feng Yan Wang Guangbo Ge Xiaokui Huo Jing Ning Xiaochi Ma 
the NSFC (81503152,81622047,81473334 and 81503201),distinguished professor of Liaoning Province;sponsored by Liaoning BaiQianWan Talents Program Innovation;the National Key Research and Development Program of China (2017YFC1700200) for financial support
Human cytosolic sulfotransferase 2 A1(SULT2A1) is an important phase II metabolic enzyme. The detection of SULT2A1 is helpful for the functional characterization of SULT2A1 and diagnosis of its related diseases. Howev...
关键词：SULFOTRANSFERASE 2A1 SULFATION Arenobufagin PROBE SELECTIVE SUBSTRATE 
Genetics and pathophysiology of mammalian sulfate biology被引量：1
《Journal of Genetics and Genomics》2017年第1期7-20,共14页Rachel Langford Elizabeth Hurrion Paul A. Dawson 
supported by the Mater Medical Research Institute,Mater Foundation and a Mater Foundation Research Fellowship to PAD
Nutrient sulfate is essential for numerous physiological functions in mammalian growth and development. Accordingly, disruptions to any of the molecular processes that maintain the required biological ratio of sulfona...
关键词：SULFATE Pathogenetics Transport SULFOTRANSFERASE SULFATASE PAPS 
Dopamine D1 receptor activation induces dehydroepiandrosterone sulfotransferase （SULT2A1） in HepG2 cells被引量：2
《Acta Pharmacologica Sinica》2014年第7期889-898,共10页Jiao-jiao XU Si-yuan WANG Ye CHEN Guang-ping CHEN Zai-quan LI Xue-yan SHAO Liang LI Wei LU Tian-yanZHOU 
Aim： Dopamine receptors are present in the nervous system and also widely distributed in the periphery. The aim of this study was to investigate the role of D1 subtype dopamine receptors （DRD1） in the regulation of...
关键词：DOPAMINE D1 receptor dehydroepiandrosterone sulfotransferase （SULT2A1） drug-metabolizing enzyme SKF82958 SKF38393 SCH23390 siRNA HepG2 cell 
Drosophila heparan sulfate 3-0 sulfotransferase B Null Mutant Is Viable and Exhibits No Defects in Notch Signaling
《Journal of Genetics and Genomics》2014年第7期369-378,共10页Yueqin Guo Ying Feng Zhouhua Li Xinhua Lin 
supported by the grants from the National Basic Research Program of China(Nos.2011CB943901,2011CB943902 and 2011CB943802);the National Natural Science Foundation of China(Nos.31030049,31271582 and 31071284);Strategic Priority Research Program of the Chinese Academy of Sciences Grant(No.XDA01010101)
Heparan sulfate proteoglycans （HSPGs） are critically involved in a variety of biological events. The functions of HSPGs are determined by the nature of the core proteins and modifications of heparan sulfate （HS） g...
关键词：DROSOPHILA heparan sulfate proteoglycans Hs3st-A Hs3st-B NOTCH 
Comparison of dopamine with levodopa in the induction of aryl sulfotransferases and estrogen sulfotransferase in rat liver
《Journal of Chinese Pharmaceutical Sciences》2014年第7期471-479,共9页邵雪岩 李健 王思媛 陈广平 许娇娇 冀希炜 李良 卢炜 周田彦 
National Natural Science Foundation of China(Grant No.81072699)
Sulfotransferases（SULTs） are one of the most important phase II drug-metabolizing enzymes. Among them, aryl sulfotransferases（SULT1A1） and estrogen sulfotransferase（EST, SULT1E1） belong to the rSULT1 family that...
关键词：DOPAMINE LEVODOPA Dopamine receptors SULFOTRANSFERASE INDUCTION 
Shewanella piezotolerans WP3中sulfotransferase基因的克隆表达与活性研究
《汕头大学学报（自然科学版）》2013年第1期28-33,共6页韦海澜 李艳霞 李升康 
广东高校优秀青年创新人才培养计划资助项目(LYM09079);教育部留学回国人员启动基金资助项目
Shewanella piezotolerans WP3分离自西太平洋1914 m的深海沉积物中,是一株革兰氏阴性,耐冷、耐压且兼性厌氧的杆状细菌.初步研究证明海洋细菌中含有磺基转移酶(sulfotransferase,ST)活性.本实验中构建了WP3两个磺基转移酶基因的原核表...
关键词：S piezotolerans WP3 磺基转移酶 克隆与表达 
<i>Sulfotransferase</i>1A1 G638A polymorphism, cigarette smoking and bladder cancer risk in Taiwan
《Advances in Bioscience and Biotechnology》2012年第3期186-190,共5页Kun-Hung Shen Chia-Chang Wu Yuan-Hung Wang Steven K. Huang Thomas I. S. Hwang Chung-Hsin Yeh Guang-Dar Juang 
Cigarette smoking is a major risk factor for bladder cancer (BC). Sulfotransferase 1A1 (SULT1A1), a phase II enzyme, plays an important role in the metabolism of several carcinogens contained in cigarettes. The aim of...
关键词：BLADDER Cancer Cigarette Smoking POLYMORPHISM SULT1A1 
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