云南高校图书馆联盟文献共享服务平台- NATTOKINASE

检索规则说明：AND代表“并且”；OR代表“或者”；NOT代表“不包含”；(注意必须大写,运算符两边需空一格)

检索范例：范例一： (K=图书馆学 OR K=情报学) AND A=范并思　　　　范例二：J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual

全部期刊核心期刊 EI来源期刊 SCI来源期刊 CA来源期刊 CSCD来源期刊 CSSCI来源期刊

Nattokinase as a functional food ingredient:therapeutic applications and mechanisms in age-related diseases: 《Food Science and Human Wellness》2024年第5期2401-2409,共9页Hao Wu Qian Zhang Hao Suo Feng Xu Wanxu Huang Dan Ohtan Wang; supported by the China Postdoctoral Science Foundation(2021M693870,2022M711395);the National Natural Science Foundation of China(32000426,31971335);Department of Education of Liaoning Province(1911520092).; Consumption of natto,a traditional eastern Asian food made of fermented soybeans by Bacillus subtilis,has long been linked to healthy aging and longer human lifespan.As the key thrombolytic ingredient of natto,the ser...; 关键词：NATTOKINASE Functional food ingredient Aging-related diseases Cardiovascular diseases INFLAMMATION

Degradation of amyloid β-peptides catalyzed by nattokinase in vivo and in vitro: 《Food Science and Human Wellness》2023年第5期1905-1916,共12页Aixin Ni He Li Ruya Wang Rentong Sun Yingjiu Zhang; supported by the National Natural Science Foundation of China Program (No. 31970883)。; Amyloid-β 1-42(Aβ42)plays a pivotal role in Alzheimer disease(AD)pathogenesis. Peripheral clearance of Aβ42 largely affects its level in the brain and affects AD progression. Although nattokinase(NK)degrades Aβ40,...; 关键词：NATTOKINASE Amyloidβ-peptide DEGRADATION CATALYZE Alzheimer disease

Analysis of Main Components and Prospects of Natto被引量：1: 《Advances in Enzyme Research》2021年第1期1-9,共9页Yanchun Liu Yanxia Han Lingli Cao Xiuling Wang Shijuan Dou; The word “natto” originated from Japan, which was known as stinky bean, salt bean or silk bean in Chinese folk. Natto contains multiple functional components, including nattokinase, soybean isoflavone, γ-polyglutam...; 关键词：NATTO NATTOKINASE Cardiovascular and Cerebrovascular Diseases Functional Food

响应面法优化鹰嘴豆发酵纳豆工艺被引量：14: 《中国调味品》2019年第2期51-55,共5页罗仓学刘晓宇张雯; 鹰嘴豆作为纳豆发酵原料,以纳豆激酶(Nattokinase,NK)活性为指标,在单因素实验的基础上,利用Box-Behnken实验设计以及响应面分析优化纳豆发酵工艺。研究结果表明,鹰嘴豆的最佳发酵工艺条件为:基质含水量50%,接种量6%,发酵温度34℃,发酵...; 关键词：鹰嘴豆发酵工艺纳豆激酶(Nattokinase NK) 纳豆

Preparation and toxicity evaluation of a novel nattokinase-tauroursodeoxycholate complex被引量：6: 《Asian Journal of Pharmaceutical Sciences》2018年第2期173-182,共10页Rui Feng Jing Li Jiepeng Chen Lili Duan XinRong Liu Donghua Di Yihui Deng Yanzhi Song; Nattokinase(NK), which has been identified as a potent fibrinolytic protease, has remarkable potential in treatment of thrombolysis, and even has the ability to ameliorate chronic vein thrombosis. To reduce the hemorr...; 关键词：NATTOKINASE Tauroursodeoxycholate COMPLEX TOXICITY TEST In VITRO THROMBOLYTIC TEST

In vitro and in silico studies on fibrinolytic activity of nattokinase： A clot buster from Bacillus sp.被引量：5: 《Frontiers in Biology》2017年第3期219-225,共7页V. Mohanasrinivasan. A. Mohanapriya Swaroop Potdar Sourav Chatterji Srinath Konne Sweta Kumari S. Merlyn Keziah. C. Subathra Devi; BACKGROUND： Nattokinase （NK） is a serine protease enzyme of the subtilisin family. It exhibits a strong fibrinolytic activity. The fibrinolytic enzymes from Bacillus sp. have attracted interest as thrombolytic agen...; 关键词：nattokinase （NK） Bacillus sp. clot busters DOCKING

Effect of Tb(Ⅲ) on activity and stability of nattokinase被引量：2: 《Journal of Rare Earths》2017年第5期510-517,共8页牟小超杨仁佳张文龙杨斌盛; Project supported by the National Natural Science Foundation of China(21571117);the PhD Programs Foundation of the Ministry of Education of China(20131401110011); Nattokinase, is an effective fibrinolytic enzyme with the potential for fighting cardiovascular disease. The aim of study was to investigate the interaction of Tb（Ⅲ） with nattokinase and the impact of Tb（Ⅲ） on t...; 关键词：constants protease tetra affinity cardiovascular fighting Effect of Tb aromatic absence tryptophan

Preparation and evaluation of nattokinaseloaded self-double-emulsifying drug delivery system被引量：12: 《Asian Journal of Pharmaceutical Sciences》2015年第5期386-395,共10页Xiaona Wang Sifan Jiang Xinyue Wang Jie Liao Zongning Yin; supported by National Natural Science Foundation of China(No.81373338).; In the present study,we prepared nattokinase-loaded self-double-emulsifying drug delivery system(SDEDDS)and investigated its preliminary pharmacodynamics.The type and concentration of oil phase,inner aqueous phase and...; 关键词：Self-double-emulsifying drug delivery system NATTOKINASE Yield Release in vitro Pharmacodynamics study

Four residues of propeptide are essential for precursor folding of nattokinase被引量：5: 《Acta Biochimica et Biophysica Sinica》2014年第11期957-964,共8页Yan Jia Xinhua Cao Yu Deng Wei Bao Changyan Tang Hanjing Ding Zhongliang Zheng Guolin Zou; Subtilisin propeptide functions as an intramolecular chaperone that guides precursor folding. Nattokinase, a member of subtilisin family, is synthesized as a precursor consisting of a signal peptide, a propeptide, and...; 关键词：intramolecular chaperone PROPEPTIDE SUBTILISIN essential residues NATTOKINASE

Thermostability of Subtilisin Nattokinase Obtained by Site-Directed Mutagenesis被引量：6: 《Wuhan University Journal of Natural Sciences》2014年第3期229-234,共6页WENG Meizhi DENG Xiongwei WU Jieyuan ZOU Guolin; Supported by the National Natural Science Foundation of China(30670464,20873092,30800190);Science and Technology Project of Wuhan(200960323115); To study the thermostability of Nattokinase（subtilisin NAT,NK）,three double mutant plasmids（pET-28a-NKG61C/S98C,pET-28a-NKT22C/S87C,pET-28a-NKS24C/S87C）were constructed by site-directed mutagenesis.Target enzymes ...; 关键词：nattokinase subtilisin thermostability

NATTOKINASE