PROPEPTIDE

作品数：9被引量：38H指数：5
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相关领域：医药卫生更多>>
相关作者：贾斌骞爱荣商澎尹大川傅增祥更多>>
相关机构：西北工业大学中国科学技术大学天津医科大学汕头大学医学院第二附属医院更多>>
相关期刊：《Journal of Northeast Agricultural University(English Edition)》《Advances in Bioscience and Biotechnology》《Acta Biochimica et Biophysica Sinica》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Effects of Yishengukang decoction on expression of bone-specific alkaline phosphatase,carboxyterminal propeptide of typeⅠprocollagen,and carboxyterminal cross-linked telepeptide of typeⅠcollagen in malignant tumor patients with bone metastasis被引量：7
《Journal of Traditional Chinese Medicine》2017年第1期30-34,共5页Yin Yukun Feng Li Zhou Lei Li Jie Gao Yin Wang Ningjun Yu Jianhua Jiang Zhenglong He Shengqi Lu Dianrong Wang Fang Du Yanlin 
Wangjing Hospital,China Academy of Chinese Medical Sciences Program:Clinical Study on Improving the Life Quality of Cancer Patients by Nourishing Yin and Tonifying the Kidney(No.2007-01);Specific Science and Technology Improvement Project of Beijing Traditional Chinese Medical Science and Technology Development Fund:Clinical Study on Chinese Herbs of Bushen Huayu Combined with Hyperthermia in Treating Bone Metastatic Pain(No.KJTS2011-13);Beijing Science and Technology Program"the Capital of special":Clinical Study on Chinese Herbs of Fuzheng Jiedu Huayu in Treating Cancer Pain(Z141107002514045)
OBJECTIVE: To investigate the effect of Yishengukang decoction on the expression of the metabolic bone markers, bone-specific alkaline phosphatase(BAP), carboxyterminal propeptide of type Ⅰ procollagen(PICP), and car...
关键词：Malignant tumor Neoplasm metastasis Alkaline phosphatase Collagen type Ⅰ 
Protein Folding Mediated by an Intramolecular Chaperone: Energy Landscape for Unimolecular Pro-Subtilisin E Maturation
《Advances in Bioscience and Biotechnology》2015年第2期73-88,共16页Ezhilkani Subbian Danielle M. Williamson Ujwal Shinde 
Efficient and precise assembly of polypeptides into native functional states is critical for normal cellular processes. Understanding how a specific structure is encoded in the polypeptide sequence and what drives the...
关键词：PROPEPTIDE Dependent Folding PROTEASE Activation Subtilases ENERGETICS PROPROTEIN Convertases 
Four residues of propeptide are essential for precursor folding of nattokinase被引量：5
《Acta Biochimica et Biophysica Sinica》2014年第11期957-964,共8页Yan Jia Xinhua Cao Yu Deng Wei Bao Changyan Tang Hanjing Ding Zhongliang Zheng Guolin Zou 
Subtilisin propeptide functions as an intramolecular chaperone that guides precursor folding. Nattokinase, a member of subtilisin family, is synthesized as a precursor consisting of a signal peptide, a propeptide, and...
关键词：intramolecular chaperone PROPEPTIDE SUBTILISIN essential residues NATTOKINASE 
Effect of MSTN Propeptide and shRNA Co-expression Vector on Proliferation of Skeletal Muscle Satellite Cells
《Journal of Northeast Agricultural University(English Edition)》2014年第1期31-38,共8页Feng Lin-he Wang Xin Lu Ming Tong Hui-li Li Shu-feng Yan Yun-qin 
Supported by the Major Special Projects of New Product Training of Transgenic Organisms(zx080072008-2008)
Myostatin （MSTN） is a negative regulator of skeletal muscle growth, in order to study the effect of inhibition MSTN expression on the proliferation of bovine skeletal muscle satellite cells, we constructed co-expres...
关键词：MYOSTATIN cell proliferation flow cytometry expression vector 
The putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stability
《Protein & Cell》2013年第12期921-931,共11页Demeng Sun Qing Liu Yao He Chengliang Wang Fangming Wu Changlin Tian Jianye Zang 
This work was supported by funds from the National Basic Research Program(973 Program)(Nos.2011CB911104 and 2012CB917202);the National Natural Science Foundation of China(Grant No.31100538)to F.W.,(Grant No.31170817)to C.T.
Mycosin-1 protease(MycP1)is a serine protease anchored to the inner membrane of Mycobacterium tuberculosis,and is essential in virulence factor secretion through the ESX-1 type VII secretion system(T7SS).Bacterial phy...
关键词：type VII ESX-1 secretion system serine protease PROPEPTIDE crystal structure EspB cleavage molecular dynamic simulations 
Vitamin D deficiency: Correlation to interleukin-17, interleukin-23 and PⅢNP in hepatitis C virus genotype 4被引量：12
《World Journal of Gastroenterology》2012年第28期3738-3744,共7页Mona F Schaalan Waleed A Mohamed Hesham H Amin 
AIM: To assess vitamin D (Vit D) abnormalities in hepatitis C infected patients and their relationship with interleukin (IL)-17, IL-23 and N-terminal propeptide of type Ⅲ pro-collagen (PⅢNP) as immune response media...
关键词：Vitamin D INTERLEUKIN-17 INTERLEUKIN-23 N-terminal propeptide of type Ⅲ pro-collagen Hepatitis genotype 4 
Homologue of mammalian apolipoprotein A-II in non-mammalian vertebrates被引量：5
《Acta Biochimica et Biophysica Sinica》2009年第5期370-378,共9页Malay Choudhury Shoji Yamada Masaharu Komatsu Hideki Kishimura Seiichi Ando 
Although apolipoprotein with molecular weight 14 kDa （apo-14kDa） is associated with fish plasma highdensity lipoproteins （HDLs）, it remains to be determined whether apo-14 kDa is the homologue of mammalian apoA-II...
关键词：apolipoprotein A-II-like protein Anguilla japonica Oncorhynchus mykiss phylogenetic tree PROPEPTIDE 
Effect of Astragalus complanatus flavonoid on anti-liver fibrosis in rats被引量：8
《World Journal of Gastroenterology》2005年第37期5782-5786,共5页Chun-Yu Liu Zhen-Lun Gu Wen-Xuan Zhou Ci-Yi Guo 
AIM： To observe the anti-liver fibrosis effect of Astragalus complanatus fiavonoids （ACF） in rats. METHODS： The liver fibrosis model in rats was established by injecting interperitoneally 0.2 mL/100 g 0.5% dimethy...
关键词：Astragalus complanatus  Liver fibrosis N-propeptide of typeⅠ procollagen N-propeptide of type Ⅲ procollagen Malondialdehyde Superoxide dismutase Matrix metal protease-1 Tissue inhibitor of metal protease-1 
The Role of Propeptide in the Refolding of Human Group IB Phospholipase A_2被引量：1
《Acta Biochimica et Biophysica Sinica》2004年第9期583-588,共6页Hong-QiangCHENG] Gen-JunXU 
This work was supported by a grant from the National Natural ScienceFoundation of China (No. 39930060)
Human group IB phospholipase A2 (IB-PLA2) and its zymogen (proIB-PLA2) were purified from E. coli. Refolding was carried out by diluting the denatured forms of both IB-PLA2 and proIB-PLA2 with renaturation buf...
关键词：human group IB phospholipase A2 (IB-PLA2) REFOLDING first disulfide bond PROPEPTIDE 
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